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NCT04028700 · ClinicalTrials.gov registry record · Phase 2
The Impact of Oxidative Stress on Erythrocyte Biology
A Phase 2 study, sponsored by University of North Carolina, Chapel Hill.
- Terminated
- Registry status
- Phase 2
- Development phase
- 8
- Enrollment target
NCT04028700: Clinical Trial Phase 2 study, sponsored by University of North Carolina, Chapel Hill.
NCT04028700 is a Phase 2 study that was terminated before completion, run by University of North Carolina, Chapel Hill. The registered enrollment target is 8 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04028700, a Phase 2 study, was terminated before completion, sponsored by University of North Carolina, Chapel Hill.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 8 participants
- Enrollment target
Study Summary
This study will address if red blood cells transfused to a sickle cell patient from a donor with a glucose-6-phosphate-dehydrogenase (G6PD) enzyme deficiency have a different lifespan as measured by the percentage of red blood cells that survive post-transfusion compared to red blood cells transfused to a sickle cell patient from a donor without a G6PD enzyme deficiency.
Primary Outcome
Post-Transfusion Recovery
Interventions
- BIOLOGICAL G6PD Deficient Red Blood Cell Transfusion
- BIOLOGICAL Non-G6PD deficient Red Blood Cell Transfusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2022-01-02 |
| Est. Completion | 2024-08-16 |
| Phase | Phase 2 |
Why NCT04028700 stopped before completion
NCT04028700 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which G6PD Deficient Red Blood Cell Transfusion is the first listed.
NCT04028700 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04028700 about?
NCT04028700 is a clinical study titled "The Impact of Oxidative Stress on Erythrocyte Biology". This study will address if red blood cells transfused to a sickle cell patient from a donor with a glucose-6-phosphate-dehydrogenase (G6PD) enzyme deficiency have a different lifespan as measured by the percentage of red blood cells that survive post-transfusion compared to red blood cells transfuse...
What is the current status of trial NCT04028700?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2022-01-02. Estimated completion is 2024-08-16.
What interventions are being tested in trial NCT04028700?
The interventions under investigation include: G6PD Deficient Red Blood Cell Transfusion (BIOLOGICAL), Non-G6PD deficient Red Blood Cell Transfusion (BIOLOGICAL).
Who is sponsoring clinical trial NCT04028700?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04028700's enrollment target sits among peer trials
8 1990th of 2000 higher than 5 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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