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NCT04906499 · ClinicalTrials.gov registry record · NA
Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 7
- Enrollment target
NCT04906499: Completed NA study, sponsored by University of North Carolina, Chapel Hill.
NCT04906499 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 7 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04906499, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 7 participants
- Enrollment target
Study Summary
Osteoarthritis (OA) is a leading cause of disability worldwide that affects millions of Americans each year. Posttraumatic OA (PTOA) significantly impacts patients after anterior cruciate ligament (ACL) injury and ACL reconstruction (ACLR) with approximately 50% of patients developing PTOA within 20 years of injury or surgery. Knee joint mechanical loading measured via physical activity (i.e. daily steps) is insufficient in individuals after ACLR compared to uninjured individuals. Establishing the beneficial effects of physical activity to promote optimal free-living knee joint mechanical loading and improve knee joint health will aid in the development of cost-effective interventions that prevent PTOA and health burden of the disease.
Primary Outcome
MRI marker of T1rho relaxation times of medial femoral articular cartilage (i.e proteoglycan density) at pre-intervention (baseline)
Interventions
- BEHAVIORAL Physical Activity Promotion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2021-08-01 |
| Est. Completion | 2022-09-09 |
| Phase | NA |
What the finished NCT04906499 record still lists
NCT04906499 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Physical Activity Promotion is the first listed.
NCT04906499 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04906499 about?
NCT04906499 is a clinical study titled "Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion". Osteoarthritis (OA) is a leading cause of disability worldwide that affects millions of Americans each year. Posttraumatic OA (PTOA) significantly impacts patients after anterior cruciate ligament (ACL) injury and ACL reconstruction (ACLR) with approximately 50% of patients developing PTOA within 20...
What is the current status of trial NCT04906499?
This trial is currently completed. It is a NA study. The enrollment target is 7 participants. The study started on 2021-08-01. Estimated completion is 2022-09-09.
What interventions are being tested in trial NCT04906499?
The interventions under investigation include: Physical Activity Promotion (BEHAVIORAL).
Who is sponsoring clinical trial NCT04906499?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04906499's enrollment target sits among peer trials
7 1982nd of 2000 higher than 18 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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