University of North Carolina, Chapel Hill

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of North Carolina, Chapel Hill sits in the top decile of US sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count).

1,109 total trials 108 currently recruiting 881 completed early-phase tilt top decile by trial count

University of North Carolina, Chapel Hill: 1,109 sponsored US clinical trials, 108 recruiting.

University of North Carolina, Chapel Hill sponsors 1,109 registered US clinical trials on ClinicalTrials.gov, 108 of them currently recruiting, and 881 completed. 69 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of North Carolina, Chapel Hill ranks in the top decile of sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

881 of 962 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,109 total, page 7 of 23

COMPLETED NA

Patient Removal of Catheters After Urogynecologic Surgery

NCT04783012

COMPLETED NA

Bioavailability of SPMs in Obese Humans

NCT04701138

COMPLETED NA

Isoenergetic High Intensity Interval Training and Moderate Intensity Training in Adults With Type I Diabetes

NCT04664205

COMPLETED NA

Horyzons: Implementation in Clinical Practice

NCT04673851

COMPLETED NA

Asthma Clinics Helping Expand Cost Conversations

NCT04669080

TERMINATED Phase 2

Mouth Rinses for Inactivation of COVID-19

NCT04584684

COMPLETED NA

Examining the Efficacy of the T-STEP

NCT04612231

COMPLETED NA

Virtual Reality After Pediatric Scoliosis Surgery

NCT04584970

COMPLETED

Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults

NCT04702243

COMPLETED NA

Med-South Lifestyle Study: Phase 1

NCT04421703

COMPLETED NA

Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)

NCT04533711

COMPLETED NA

Paravertebral Block With Brachial Plexus Block for Upper Arm Arteriovenous Fistula Surgery

NCT04720079

COMPLETED NA

Study of a Personalized vs. Standard Approach to Weight Loss Recommendations

NCT04639076

COMPLETED NA

Interscalene Catheter vs. Interscalene Liposomal Bupivacaine for Arthroscopic Rotator Cuff Repair

NCT04571606

COMPLETED Phase 2

Pilot Study of Loop Diuretics Among Individuals Receiving Hemodialysis

NCT04622709

COMPLETED NA

Testing Product Messages for Colombia

NCT04567004

COMPLETED NA

Evaluating a Messaging Campaign in the United States

NCT04562636

TERMINATED Phase 2

Binge Eating & Birth Control

NCT04278755

TERMINATED NA

Prostatic Artery Embolization vs Medication for Benign Prostatic Hyperplasia

NCT04398966

COMPLETED

Pediatrician Wellbeing Program

NCT04805294

COMPLETED NA

Screening for Atrial Fibrillation With Self Pulse Monitoring

NCT05818592

COMPLETED NA

iTBS for Adolescent Depression: An Open Label Study Evaluating Safety and Efficacy of Treatment

NCT04485455

TERMINATED NA

Complex Spine Enhanced Recovery After Surgery (ERAS)

NCT04538092

COMPLETED NA

The Effect of Clear Masks in Improving Patient Relationships

NCT04595695

COMPLETED Phase 2

Coronavirus Disease 2019 (COVID-19) Antibody Plasma Research Study in Hospitalized Patients

NCT04524507

COMPLETED NA

Patient Acceptance and Preference Among Screening Modalities for Detection of Barrett's Esophagus

NCT04301986

COMPLETED Phase 2

Evaluation of Endometriosis With 18F-fluoroestradiol PET / MRI

NCT04382911

COMPLETED

Evaluation of Outcomes Related to Cerebrospinal Fluid Drain Placement

NCT04505423

COMPLETED NA

Patient Portal Use by Parents of Spanish-Speaking Children

NCT04410380

COMPLETED Phase 1

Effect of Zilretta Injection

NCT04261049

COMPLETED NA

AllyQuest Adherence App Intervention for HIV-positive Men Who Have Sex With Men and Transgender Women: Pilot Trial

NCT03916484

COMPLETED NA

Delicious Eating for Life in Southern Homes

NCT04302727

COMPLETED NA

Assessing Adherence to Home Telemedicine in Individuals With Chronic Obstructive Pulmonary Disease (COPD)

NCT04369885

COMPLETED NA

Reducing Cardiovascular Disease Risk in Perimenopausal Latinas

NCT04313751

COMPLETED

Eating Disorders Genetics Initiative

NCT04378101

COMPLETED NA

Testing of a Mobile Web App to Decrease Posttraumatic Stress Symptoms in Women After Sexual Assault

NCT04334356

COMPLETED NA

HIV Reengagement and Assessment Mobile Program (Project RAMP)

NCT04151498

COMPLETED NA

Studying the Impact of Product Packaging in a Virtual Store Environment

NCT04381481

COMPLETED

COVID-19 Household Transmission Study

NCT04445233

COMPLETED

ScreenNC, a Study to Determine the Number of Asymptomatic Individuals Who Have Antibodies to the Virus That Causes COVID-19

NCT04367740

COMPLETED NA

Utility Of Mutational Load As A Predictor For Endoscopic Treatment Response In Barrett's Esophagus

NCT04316975

COMPLETED NA

Study of Telemedicine Stress Management and Lifestyle Group Intervention for HCV Patients

NCT04198584

COMPLETED NA

Promoting Stretching Exercise to Reduce Cardiovascular Health Risk in Late Pregnant Women With Obesity

NCT04291560

COMPLETED NA

De-prescribing Program to Evaluate Falls in Older Adults

NCT04272671

COMPLETED Phase 2

Neurobiology of Bulimia Nervosa

NCT04225221

COMPLETED NA

Reducing the Transition From Acute to Chronic Musculoskeletal Pain Among Older Adults

NCT04118595

COMPLETED NA

Impact of Warnings on Sugar-Sweetened Beverages

NCT04223687

COMPLETED NA

STUN (STop UNhealthy) Alcohol Use Now! Implementing Evidence-Based Services for Unhealthy Alcohol Use in Primary Care

NCT04317989

COMPLETED NA

Establishing Novel Antiretroviral Imaging for Hair to Elucidate Non-Adherence (ENLIGHTEN)

NCT04232540

COMPLETED NA

Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System

NCT04207333

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Phase Distribution

PhaseTrial count
Phase 1 111
Phase 2 92
Phase 3 13
Phase 4 56

What is open in the University of North Carolina, Chapel Hill pipeline

108 recruiting of 1,109 indexed (10% open); 881 completed (79%).

Phase mix: 69 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of North Carolina, Chapel Hill: open-pipeline peers nationwide

Peers matched on 1,109 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share University of North Carolina, Chapel HillUniversity of FloridaWake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthChildren's Hospitals and Clinics of MinnesotaCytokineticsSanofiOhio University
University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,109 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this University of North Carolina, Chapel Hill page

1,109 registered trials is a research-attention snapshot, not an endorsement of University of North Carolina, Chapel Hill or any single study.

  • 108 of University of North Carolina, Chapel Hill's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition University of North Carolina, Chapel Hill studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of North Carolina, Chapel Hill pipeline card: 1,109 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.