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NCT07040449 · ClinicalTrials.gov registry record · NA
Stress Trajectories and Anhedonia in Adolescence Research Study
A NA study of Anhedonia and Adolescent Development, sponsored by University of North Carolina, Chapel Hill.
- Recruiting
- Registry status
- NA
- Development phase
- 192
- Enrollment target
- 1
- Study location
NCT07040449 is a NA study of Anhedonia and Adolescent Development that is actively recruiting participants, run by University of North Carolina, Chapel Hill. The registered enrollment target is 192 participants, above the 101-participant average among 21 other Anhedonia trials with a reported enrollment target (90% higher). The trial reports 1 study location across 1 state.
The verdict
NCT07040449, a NA study of Anhedonia and Adolescent Development, is actively recruiting participants, sponsored by University of North Carolina, Chapel Hill.
- RECRUITING
- Registry status
- NA
- Development phase
- 192 participants
- Enrollment target
- 1
- Study location
Study Summary
This project will examine how multiple biological measures from the brain and the body's stress response system contribute to anhedonia (the loss of pleasure) in adolescence. The goal of this project is to see if it is possible to combine these biological measures to describe different patterns of activity in the brain and body that adolescents may have in response to stress. The main question this study aims to answer is whether different patterns of activity in the brain and body are related to whether adolescents develop anhedonia and how high or low levels of anhedonia are over time. This study will enroll 192 adolescents who are between 13 and 15 years. Adolescents will complete tasks three times: at the beginning of the study, 10 months after that, and then 10 months after that. In total, they will be part of the study for 20 months. At each time, adolescents will complete surveys, provide samples of spit to measure hormones and provide pictures of their brain to measure brain activity, participate in mildly stressful tasks, and complete different activities that measure how they think. The investigators will also ask each adolescent's parent or legal guardian to answer some surveys about themselves and their child.
Conditions Studied
Interventions
- BEHAVIORAL Montreal Imaging Stress Task
- BEHAVIORAL Trier Social Stress Test for Children
Study Locations (1)
North Carolina
- University of North Carolina at Chapel Hill - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 192 participants |
| Start Date | 2025-03-12 |
| Est. Completion | 2030-02 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07040449
The ClinicalTrials.gov registry entry for NCT07040449 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 192 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 101-participant average among 21 other Anhedonia trials with a reported enrollment target (90% higher). The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Anhedonia appearing as the primary indexed condition, and to 2 interventions - of which Montreal Imaging Stress Task is the first listed.
NCT07040449 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT07040449 about?
NCT07040449 is a clinical study titled "Stress Trajectories and Anhedonia in Adolescence Research Study". This project will examine how multiple biological measures from the brain and the body's stress response system contribute to anhedonia (the loss of pleasure) in adolescence. The goal of this project is to see if it is possible to combine these biological measures to describe different patterns of a...
What is the current status of trial NCT07040449?
This trial is currently recruiting. It is a NA study. The enrollment target is 192 participants. The study started on 2025-03-12. Estimated completion is 2030-02.
What conditions does trial NCT07040449 study?
This clinical trial studies the following conditions: Anhedonia, Adolescent Development, Stress Response.
What interventions are being tested in trial NCT07040449?
The interventions under investigation include: Montreal Imaging Stress Task (BEHAVIORAL), Trier Social Stress Test for Children (BEHAVIORAL).
Who is sponsoring clinical trial NCT07040449?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07040449 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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