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NCT06331052 · ClinicalTrials.gov registry record · NA
3-D Tractography FUS Ablation for Essential Tremor
A NA study of Essential Tremor, sponsored by University of North Carolina, Chapel Hill.
- Recruiting
- Registry status
- NA
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT06331052: Recruiting NA study of Essential Tremor, sponsored by University of North Carolina, Chapel Hill.
NCT06331052 is a NA study of Essential Tremor that is actively recruiting participants, run by University of North Carolina, Chapel Hill. The registered enrollment target is 24 participants, below the 402-participant average among 41 other Essential Tremor trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06331052, a NA study of Essential Tremor, is actively recruiting participants, sponsored by University of North Carolina, Chapel Hill.
- RECRUITING
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators propose to advance Vim-FUSA (Ventral Intermediate Nucleus - Focused Ultrasound Ablation) with the support of 3-D tractography, a neuroimaging technique to visually represent nerve tracts within the brain. The investigators hypothesize that 3-D tractography Vim-FUSA will improve the Vim ablation compared to standard Vim-FUSA and prove safe and feasible in the clinical setting. The investigators also hypothesize that intraoperative magnetic resonance (i-MR) monitoring will differentiate ablated tissue from immediate perilesional edema and accurately predict the Vim-FUSA clinical outcomes.
Primary Outcome
Feasibility is defined as the ability to complete the procedure without side effects.
Conditions Studied
Interventions
- DEVICE MR-guided Focused Ultrasound Ablation
Study Locations (1)
North Carolina
- University of North Carolina at Chapel Hill - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2024-02-28 |
| Est. Completion | 2028-02-28 |
| Phase | NA |
What NCT06331052 shows while recruiting
NCT06331052 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 402-participant average among 41 other Essential Tremor trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Essential Tremor appearing as the primary indexed condition, and to 1 intervention - of which MR-guided Focused Ultrasound Ablation is the first listed.
NCT06331052 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06331052 about?
NCT06331052 is a clinical study titled "3-D Tractography FUS Ablation for Essential Tremor". The investigators propose to advance Vim-FUSA (Ventral Intermediate Nucleus - Focused Ultrasound Ablation) with the support of 3-D tractography, a neuroimaging technique to visually represent nerve tracts within the brain. The investigators hypothesize that 3-D tractography Vim-FUSA will improve the...
What is the current status of trial NCT06331052?
This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2024-02-28. Estimated completion is 2028-02-28.
What conditions does trial NCT06331052 study?
This clinical trial studies the following conditions: Essential Tremor.
What interventions are being tested in trial NCT06331052?
The interventions under investigation include: MR-guided Focused Ultrasound Ablation (DEVICE).
Who is sponsoring clinical trial NCT06331052?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06331052 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06331052's enrollment target sits among peer trials
24 31st of 41 higher than 10 of 41 other Essential Tremor trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Essential Tremor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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