University of North Carolina, Chapel Hill

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of North Carolina, Chapel Hill sits in the top decile of US sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count).

1,109 total trials 108 currently recruiting 881 completed early-phase tilt top decile by trial count

University of North Carolina, Chapel Hill: 1,109 sponsored US clinical trials, 108 recruiting.

University of North Carolina, Chapel Hill sponsors 1,109 registered US clinical trials on ClinicalTrials.gov, 108 of them currently recruiting, and 881 completed. 69 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of North Carolina, Chapel Hill ranks in the top decile of sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

881 of 962 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,109 total, page 3 of 23

RECRUITING NA

Food as Medicine for HIV and Diabetes

NCT05026723

RECRUITING

Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis

NCT06057714

RECRUITING NA

Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury

NCT04875052

RECRUITING Phase 1

Investigating Whether Acute Elevation of Fatty Acid Levels Alters Cerebral Glucose Transport and Metabolism

NCT04328337

RECRUITING

Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses

NCT04117360

RECRUITING NA

Synergistic Activity of Human Milk Nutrients and Infant Cognition

NCT03838536

RECRUITING

Pharmacokinetics of Off Label Pediatric Medications

NCT01286519

RECRUITING

Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease

NCT00807482

ACTIVE NOT RECRUITING NA

Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program

NCT07534254

ACTIVE NOT RECRUITING NA

Omega-3 Supplementation for Pediatric Migraine

NCT06899074

ACTIVE NOT RECRUITING NA

Collaborate and Leverage Evidence in African American Rural Network

NCT06730633

ACTIVE NOT RECRUITING

Long-term Outcomes of Complex Conversion Total Hip Arthroplasty

NCT06533020

ACTIVE NOT RECRUITING NA

Perineal Massage for Pessary Examinations

NCT06416982

ACTIVE NOT RECRUITING Phase 2

Anifrolumab for Hidradenitis Suppurativa

NCT06374212

ACTIVE NOT RECRUITING Phase 4

Dupilumab for Eosinophilic Esophagitis With Severe Strictures

NCT06352073

ACTIVE NOT RECRUITING NA

Forging New Paths: Building Interventions to Treat Criminogenic Needs in Community Based Mental Health Settings

NCT06290648

ACTIVE NOT RECRUITING Phase 2

Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study

NCT06158113

ACTIVE NOT RECRUITING NA

CommunityRx-Cardiovascular Disease

NCT06264726

ACTIVE NOT RECRUITING Phase 2

Sodium Citrate in Smell Retraining for People With Post-COVID-19 Olfactory Dysfunction

NCT06204432

ACTIVE NOT RECRUITING NA

Improving the Health of Parents and Their Adolescent and Transition-age Youth With Intellectual and Developmental Disabilities

NCT05986305

ACTIVE NOT RECRUITING

PROs Following Low-dose Irradiation for Osteoarthritis

NCT05705947

ACTIVE NOT RECRUITING NA

AF at Home: A Virtual Education Program for Patients With Atrial Fibrillation (AF)

NCT05810896

ACTIVE NOT RECRUITING NA

The Immune Directed Individualized Elimination Therapy (iDIET) Study

NCT05543512

ACTIVE NOT RECRUITING NA

Atrial Fibrillation (AF) and Electrocardiogram (EKG) Interpretation Project ECHO

NCT05890274

ACTIVE NOT RECRUITING NA

Water From Bottles to Establish Strong Teeth

NCT04893681

ACTIVE NOT RECRUITING NA

Food As MedicinE for Diabetes

NCT04828785

ACTIVE NOT RECRUITING Phase 1

Human Autologous Lung Stem Cell Transplant for Idiopathic Pulmonary Fibrosis

NCT04262167

ACTIVE NOT RECRUITING Phase 1

NFL LONG Prospective Study

NCT04263337

ACTIVE NOT RECRUITING NA

Transcutaneous ARFI Ultrasound for Differentiating Carotid Plaque With High Stroke Risk

NCT04063709

ACTIVE NOT RECRUITING NA

Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE)

NCT03554356

ACTIVE NOT RECRUITING NA

A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy

NCT03417297

ACTIVE NOT RECRUITING

Risk Factors and Biomarkers for Diagnosis and Treatment of EoE

NCT01988285

ACTIVE NOT RECRUITING

Study of COPD Subgroups and Biomarkers

NCT01969344

ACTIVE NOT RECRUITING

Genetic Modifiers of Cystic Fibrosis (CF) Liver Disease

NCT00804583

ACTIVE NOT RECRUITING

Gene Modifiers of Cystic Fibrosis Lung Disease

NCT00037765

NOT YET RECRUITING NA

Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities

NCT06915428

NOT YET RECRUITING NA

Feasibility, Acceptability, and Safety Trial of Brief, Breath Control-Focused Acceptance and Commitment Therapy in Adults With Chronic Cough

NCT07566117

NOT YET RECRUITING NA

Marine Lipids Ease Painful TMD

NCT07437313

NOT YET RECRUITING Phase 2

A Trial of Upadacitinib for Non-responsive Eosinophilic Esophagitis

NCT07588568

NOT YET RECRUITING NA

Comparing the Effects of Front-of-Package Labeling Schemes in Indonesia

NCT07526584

NOT YET RECRUITING Phase 4

Teen Vulnerability to Irritability: Brain and Estrogen Changes

NCT07544966

NOT YET RECRUITING Phase 1

Anakinra Rescue Treatment for Moderate Asthma Attacks (ARTMA)

NCT07600190

NOT YET RECRUITING Phase 2

UNC Cashew Sublingual Immunotherapy

NCT07170540

NOT YET RECRUITING NA

Integrating New Skills Into Diabetes Education With CGM

NCT07463209

NOT YET RECRUITING NA

Reducing Post-Operative Opioid Prescribing in Southeastern North Carolina

NCT07566182

NOT YET RECRUITING Phase 2

Mast Cell Treatment in Post-tick Bite Illness (PTBI)

NCT07526558

COMPLETED NA

AI Tool to Reduce Clinician Documentation Burden

NCT07498582

NOT YET RECRUITING NA

Adolescent Mental Health Parenting Program for Child-Adult Relationship Enhancement

NCT07303062

COMPLETED NA

Mobile Alcohol Use Intervention

NCT07126613

COMPLETED NA

Testing Non-nutritive Sweetener Labels in Chile

NCT06842693

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Phase Distribution

PhaseTrial count
Phase 1 111
Phase 2 92
Phase 3 13
Phase 4 56

What is open in the University of North Carolina, Chapel Hill pipeline

108 recruiting of 1,109 indexed (10% open); 881 completed (79%).

Phase mix: 69 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of North Carolina, Chapel Hill: open-pipeline peers nationwide

Peers matched on 1,109 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share University of North Carolina, Chapel HillUniversity of FloridaWake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthChildren's Hospitals and Clinics of MinnesotaCytokineticsSanofiOhio University
University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,109 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this University of North Carolina, Chapel Hill page

1,109 registered trials is a research-attention snapshot, not an endorsement of University of North Carolina, Chapel Hill or any single study.

  • 108 of University of North Carolina, Chapel Hill's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition University of North Carolina, Chapel Hill studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University of North Carolina, Chapel Hill pipeline card: 1,109 registered trials from official public datasets.Report a data error.