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NCT06072677 · ClinicalTrials.gov registry record · NA
Adolescent Mood During Puberty and Testosterone
A NA study of Adolescent Depression, sponsored by University of North Carolina, Chapel Hill.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06072677: Recruiting NA study of Adolescent Depression, sponsored by University of North Carolina, Chapel Hill.
NCT06072677 is a NA study of Adolescent Depression that is actively recruiting participants, run by University of North Carolina, Chapel Hill. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06072677, a NA study of Adolescent Depression, is actively recruiting participants, sponsored by University of North Carolina, Chapel Hill.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention deficit hyperactivity disorder (ADHD). This divergence between the sexes during puberty suggests sex-specific pathways of risk and differential effects of sex hormones. The purpose of this research is to determine: 1) sex-specific neural and endocrine features of the pubertal transition that may mediate sex differences in adolescent mood disorders, and 2) the neurophysiological basis of susceptibility to hormone change during puberty.
Primary Outcome
The 20-item Center for Epidemiological Studies Depression Scale for Children (CES-DC) will be the primary measure of severity of depressive symptoms. Each item is rated 0 (not at all) to 3 (a lot), with items 4, 8, 12, and 16 being reversed scored. The total CES-DC score may range from 0-60. Higher scores indicate more severe depressive symptoms. Scores of 15 or greater are suggestive of significant depressive symptoms. The overall CES-DC score will be assessed at the end of each week in the stu
Conditions Studied
Interventions
- BEHAVIORAL Healthy Minds Program
Study Locations (1)
North Carolina
- Carolina Crossing B, Suite 1 - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-08-24 |
| Est. Completion | 2027-12 |
| Phase | NA |
What NCT06072677 shows while recruiting
NCT06072677 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Adolescent Depression appearing as the primary indexed condition, and to 1 intervention - of which Healthy Minds Program is the first listed.
NCT06072677 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06072677 about?
NCT06072677 is a clinical study titled "Adolescent Mood During Puberty and Testosterone". Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention deficit hyperactivity disorder (ADHD). This divergence between the sexes...
What is the current status of trial NCT06072677?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2023-08-24. Estimated completion is 2027-12.
What conditions does trial NCT06072677 study?
This clinical trial studies the following conditions: Adolescent Depression.
What interventions are being tested in trial NCT06072677?
The interventions under investigation include: Healthy Minds Program (BEHAVIORAL).
Who is sponsoring clinical trial NCT06072677?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06072677 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Adolescent Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06072677's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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