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NCT00843375 · ClinicalTrials.gov registry record
Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas
A clinical trial of Colonic Neoplasms, sponsored by University of Michigan Rogel Cancer Center.
- Recruiting
- Registry status
- 1,200
- Enrollment target
- 13
- Study locations
NCT00843375: Recruiting study of Colonic Neoplasms, sponsored by University of Michigan Rogel Cancer Center.
NCT00843375 is a study of Colonic Neoplasms that is actively recruiting participants, run by University of Michigan Rogel Cancer Center. The registered enrollment target is 1,200 participants, below the 1,437-participant average among 14 other Colonic Neoplasms trials with a reported enrollment target (16% lower). The trial reports 13 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00843375, a study of Colonic Neoplasms, is actively recruiting participants, sponsored by University of Michigan Rogel Cancer Center.
- RECRUITING
- Registry status
- 1,200 participants
- Enrollment target
- 13
- Study locations
Study Summary
Colon cancer is the second most common cancer in men and women. It is a disease that can be prevented if it is found early. Colonoscopy is still the best screening tool for colon cancer and the polyps that turn into colon cancer. However, due to a variety of factors, including affordability, time, and age, not all patients are able to be screened. Researchers are working on other options for early detection that are as accurate as colonoscopy. The purpose of this study if to determine if stool or blood can be used to detect colon cancers as early or earlier than colonoscopy. The researchers plan to use these samples to learn about specific proteins (also known as biomarkers) that may indicate colon polyps, colon cancer or an increased risk of developing colon cancer. In order to learn more about preventing and detecting colon and rectal cancer, we are collecting samples from subjects with cancer, adenomas, and colonoscopies who may be at risk for polyps.
Primary Outcome
Blood samples, up to 60 mls, will be obtained according to standard operating procedures. Subjects will collect stool samples per the schedule in the study calendar. Collection of Frozen Normal and Adenoma or Cancer Tissue: For individuals with large adenomas who are undergoing endoscopic resection, the fresh surgical sample will be obtained by the endoscopist.
Conditions Studied
Study Locations (13)
California
- Cedars-Sinai Medical Center - Los Angeles
Illinois
- Carle Cancer Center - Urbana
Massachusetts
- Dana Farber Cancer Institute - Boston
Michigan
- University of Michigan - Ann Arbor
Minnesota
- University of Minnesota - Minneapolis
New York
- NYU Langone Health - New York
North Carolina
- University of North Carolina - Chapel Hill
Oregon
- Oregon Health and Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,200 participants |
| Start Date | 2019-08-07 |
| Est. Completion | 2028-03 |
What NCT00843375 shows while recruiting
NCT00843375 is an observational study that tracks outcomes without assigning an intervention. Its 1,200 participants enrollment target places it among the larger protocols in the corpus, below the 1,437-participant average among 14 other Colonic Neoplasms trials with a reported enrollment target (16% lower).
The record links to 1 condition, with Colonic Neoplasms appearing as the primary indexed condition, and to 0 interventions.
NCT00843375 lists 13 locations in 13 states (California, Illinois, Massachusetts).
Frequently Asked Questions
What is clinical trial NCT00843375 about?
NCT00843375 is a clinical study titled "Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas". Colon cancer is the second most common cancer in men and women. It is a disease that can be prevented if it is found early. Colonoscopy is still the best screening tool for colon cancer and the polyps that turn into colon cancer. However, due to a variety of factors, including affordability, time, a...
What is the current status of trial NCT00843375?
This trial is currently recruiting. The enrollment target is 1,200 participants. The study started on 2019-08-07. Estimated completion is 2028-03.
What conditions does trial NCT00843375 study?
This clinical trial studies the following conditions: Colonic Neoplasms.
Who is sponsoring clinical trial NCT00843375?
This trial is sponsored by University of Michigan Rogel Cancer Center, which has 292 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00843375 being conducted?
This trial has 13 study locations across California, Illinois, Massachusetts, Michigan, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colonic Neoplasms
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00843375's enrollment target sits among peer trials
1,200 4th of 14 higher than 11 of 14 other Colonic Neoplasms trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colonic Neoplasms trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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