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NCT06641310 · ClinicalTrials.gov registry record · NA

Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)

A NA study of Familial Adenomatous Polyposis, sponsored by University of Michigan Rogel Cancer Center.

Recruiting
Registry status
NA
Development phase
32
Enrollment target
2
Study locations

NCT06641310 is a NA study of Familial Adenomatous Polyposis that is actively recruiting participants, run by University of Michigan Rogel Cancer Center. The registered enrollment target is 32 participants, below the 245-participant average among 10 other Familial Adenomatous Polyposis trials with a reported enrollment target (87% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT06641310, a NA study of Familial Adenomatous Polyposis, is actively recruiting participants, sponsored by University of Michigan Rogel Cancer Center.

RECRUITING
Registry status
NA
Development phase
32 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this phase 1a/b trial is to find out what amount of exercise would be best to use for preventing recurrence of colorectal polyps. It involves following one of four different amounts of exercise regimens on a treadmill for 26 weeks. A treadmill will be placed in each study participant's home for the duration of the study. The exercise regimen will be personalized for each participant and monitored remotely by exercise personnel. The in-person study visits occur during the usual standard of care endoscopy exam and during a follow-up exam that is 26 weeks later. Small rectal tissue biopsies, about the size of a grain of rice, will be taken before and after 26 weeks of exercise. The study visits also involve questionnaires, a stool sample, and a blood sample. This study will inform the design of larger, future trials to investigate whether or not recurrence of polyps can be achieved with exercise.

Interventions

  • PROCEDURE Exercise Therapy

Study Locations (2)

Michigan

  • University of Michigan Rogel Cancer Center - Ann Arbor

Ohio

  • Cleveland Clinic Foundation - Cleveland

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2026-03
Est. Completion 2028-03-01
Phase NA

What the Registry Record Tells You About NCT06641310

The ClinicalTrials.gov registry entry for NCT06641310 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 245-participant average among 10 other Familial Adenomatous Polyposis trials with a reported enrollment target (87% lower). The listed sponsor is University of Michigan Rogel Cancer Center, which has 292 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Familial Adenomatous Polyposis appearing as the primary indexed condition, and to 1 intervention - of which Exercise Therapy is the first listed.

NCT06641310 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Michigan, Ohio.

Frequently Asked Questions

What is clinical trial NCT06641310 about?

NCT06641310 is a clinical study titled "Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)". The purpose of this phase 1a/b trial is to find out what amount of exercise would be best to use for preventing recurrence of colorectal polyps. It involves following one of four different amounts of exercise regimens on a treadmill for 26 weeks. A treadmill will be placed in each study participant'...

What is the current status of trial NCT06641310?

This trial is currently recruiting. It is a NA study. The enrollment target is 32 participants. The study started on 2026-03. Estimated completion is 2028-03-01.

What conditions does trial NCT06641310 study?

This clinical trial studies the following conditions: Familial Adenomatous Polyposis.

What interventions are being tested in trial NCT06641310?

The interventions under investigation include: Exercise Therapy (PROCEDURE).

Who is sponsoring clinical trial NCT06641310?

This trial is sponsored by University of Michigan Rogel Cancer Center, which has 292 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06641310 being conducted?

This trial has 2 study locations across Michigan, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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