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NCT02271815 · ClinicalTrials.gov registry record
A Clinical and Imaging Study to Evaluate a Novel Dentifrice
A clinical trial, sponsored by University of California, Irvine.
- Completed
- Registry status
- 194
- Enrollment target
NCT02271815: Completed study, sponsored by University of California, Irvine.
NCT02271815 is a clinical trial that has completed, run by University of California, Irvine. The registered enrollment target is 194 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02271815 has completed, sponsored by University of California, Irvine.
- COMPLETED
- Registry status
- 194 participants
- Enrollment target
Study Summary
There is a need for toothpastes that more effectively remove oral biofilm, inhibit biofilm re-formation and support periodontal health. This is particularly important for patients with long-term orthodontic fixtures or prosthodontic appliances, and also for debilitated, diabetic and immunocompromised patients. The objective of this study is to evaluate the effects of toothpastes on plaque presence and removal, gingival and periodontal health, dental hard tissue mineralization, erosion, abrasion, and microstructure as well as dry/sore mouth. In addition to clinical scoring and photographs, tooth and gum sensitivity, saliva volume, pH and buffering and enamel health may be evaluated using tooth samples worn on removable dental retainers. These samples will be examined outside of the mouth using advanced optical techniques such as Optical Coherence Tomography (OCT), Fluorescence, various forms of microscopy and spectroscopy.
Primary Outcome
Gingival Index
Interventions
- OTHER Oral Hygiene
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 194 participants |
| Start Date | 2014-10 |
| Est. Completion | 2021-06 |
What the finished NCT02271815 record still lists
NCT02271815 is an observational study that tracks outcomes without assigning an intervention. The registered 194 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Oral Hygiene is the first listed.
NCT02271815 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02271815 about?
NCT02271815 is a clinical study titled "A Clinical and Imaging Study to Evaluate a Novel Dentifrice". There is a need for toothpastes that more effectively remove oral biofilm, inhibit biofilm re-formation and support periodontal health. This is particularly important for patients with long-term orthodontic fixtures or prosthodontic appliances, and also for debilitated, diabetic and immunocompromise...
What is the current status of trial NCT02271815?
This trial is currently completed. The enrollment target is 194 participants. The study started on 2014-10. Estimated completion is 2021-06.
What interventions are being tested in trial NCT02271815?
The interventions under investigation include: Oral Hygiene (OTHER).
Who is sponsoring clinical trial NCT02271815?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
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