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NCT02199171 · ClinicalTrials.gov registry record · Phase 1

Heated Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Peritoneal Cancer

A Phase 1 study, sponsored by University of California, Irvine.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target

NCT02199171: Completed Phase 1 study, sponsored by University of California, Irvine.

NCT02199171 is a Phase 1 study that has completed, run by University of California, Irvine. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02199171, a Phase 1 study, has completed, sponsored by University of California, Irvine.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and best dose of heated carboplatin given into the abdomen at the time of surgery in treating patients with stage II-IV ovarian, fallopian tube, or peritoneal cancer. Drugs used in chemotherapy, such as carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Heating oxaliplatin and infusing it directly into the area around the tumor during surgery may kill more tumor cells.

Primary Outcome

MTD of HIPEC carboplatin, defined as the dose level with \< 2 patients of 6 experiencing dose-limiting toxicities, graded according to the National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0. Identified using the continual reassessment method.

Interventions

  • DRUG carboplatin

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2014-07
Est. Completion 2017-10
Phase Phase 1
University of California, Irvine

368 total trials

What the finished NCT02199171 record still lists

NCT02199171 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 1 intervention - of which carboplatin is the first listed.

NCT02199171 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02199171 about?

NCT02199171 is a clinical study titled "Heated Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Peritoneal Cancer". This phase I trial studies the side effects and best dose of heated carboplatin given into the abdomen at the time of surgery in treating patients with stage II-IV ovarian, fallopian tube, or peritoneal cancer. Drugs used in chemotherapy, such as carboplatin, work in different ways to stop the growt...

What is the current status of trial NCT02199171?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2014-07. Estimated completion is 2017-10.

What interventions are being tested in trial NCT02199171?

The interventions under investigation include: carboplatin (DRUG).

Who is sponsoring clinical trial NCT02199171?

This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02199171's enrollment target sits among peer trials

30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02199171, the US trial registry maintained by the National Library of Medicine. NCT02199171 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.