University Hospitals Cleveland Medical Center

Open enrollment with a later-stage pipeline tilt

According to ClinicalTrials.gov-derived indexes, University Hospitals Cleveland Medical Center sits in the top decile of US sponsors by registered trial count (#142 of 15,742 sponsors by registered trial count).

230 total trials 42 currently recruiting 154 completed later-stage tilt top decile by trial count

University Hospitals Cleveland Medical Center: 230 sponsored US clinical trials, 42 recruiting.

University Hospitals Cleveland Medical Center sponsors 230 registered US clinical trials on ClinicalTrials.gov, 42 of them currently recruiting, and 154 completed. 48 of these trials are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Bipolar Disorder, with 6 trials.

Top-decile sponsor footprint

University Hospitals Cleveland Medical Center ranks in the top decile of sponsors by registered trial count (#142 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 52/100

154 of 181 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (85.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

230 total, page 3 of 5

COMPLETED Phase 2

Monocyte Biomarkers in Moderate to Severe Plaque Psoriasis Subjects Treated With Apremilast

NCT03442088

COMPLETED Early Phase 1

Pain Management in Outpatient Urologic Procedures

NCT03393364

COMPLETED

Hemoglobin Desaturation in Sickle Cell Disease

NCT03908385

COMPLETED NA

Resourcefulness Intervention With Parents of Technology-Dependent Children

NCT03301831

TERMINATED NA

Effect of Non-Dissection of the Inferior Rectus Sheath on Intraoperative Blood Loss

NCT02762773

COMPLETED Phase 4

The Effectiveness of Kuvan in Amish PKU Patients

NCT02677870

COMPLETED NA

TRUST Study of Adolescent Weight Self-Management

NCT03016247

TERMINATED NA

Safety of Immediate Skin-to-Skin Contact After Vaginal Birth in Vigorous Late-Preterm Neonates

NCT03585192

TERMINATED NA

The Effect of Abdominal Binder Use on Postoperative Pain and Mobility in Patients Undergoing Pelvic Surgery

NCT03684304

COMPLETED Phase 4

Determining the Prognostic Value of Continuous Intrathecal Infusion

NCT03523000

COMPLETED

Sickle Cell Disease, Hemechip

NCT03948516

COMPLETED NA

BEATS 2: Music Therapy in Sickle Cell

NCT03233269

TERMINATED Phase 3

L-Menthol Injection as a Novel Technique During Colonoscopy

NCT02588248

COMPLETED Phase 4

Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery

NCT03052816

TERMINATED Phase 1

Efficacy of Buprenorphine on Postoperative Endodontic Analgesia

NCT03268278

COMPLETED NA

Resourcefulness Training and Decentering on Self-Management in Caregivers of Technology Dependent Children

NCT02993887

COMPLETED NA

Improving Value of Care for Patients With Severe Stasis Dermatitis

NCT03022786

COMPLETED Early Phase 1

Effect of Vitamin D After Application With Valchlor

NCT02968446

COMPLETED Phase 1

Phase I, Placebo-Controlled, Blinded Pilot Study of Ipratropium in Children Admitted to the ICU With Status Asthmaticus

NCT02872597

COMPLETED

The Cleveland Cardiometabolic Cohort

NCT03059121

COMPLETED Phase 1

Safety and Tolerability Study of Allogeneic Mesenchymal Stem Cell Infusion in Adults With Cystic Fibrosis

NCT02866721

TERMINATED

The Role of Molecules in Blood Cells for Diagnosing Bipolar Disorders

NCT02804334

COMPLETED Phase 4

Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery

NCT02509312

COMPLETED Phase 4

Patient Controlled Intrathecal Analgesia With Bupivacaine for Chronic Low Back Pain

NCT02886286

TERMINATED NA

Feasibility Study of Couple Therapy Treatment for Situational Couple Violence

NCT03498638

COMPLETED

Rostral Dorsal Cingulum Bundle Connectivity in Patients With Bipolar Disorder

NCT02655978

COMPLETED Phase 4

Mineralocorticoid Receptor Antagonism Clinical Evaluation in Atherosclerosis Trial

NCT02169089

COMPLETED

Goal Achievement and Patient Satisfaction in Benign Hysterectomy

NCT02621710

COMPLETED NA

Music Therapy in Sickle Cell Transition Study

NCT02466555

COMPLETED Phase 4

Inflammation and Thrombosis in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (TAVR)

NCT02486367

COMPLETED NA

Impact of Fitbit Plus Weight Management Program on Physical Activity and Metabolic Disease in Obese Adolescents

NCT02507791

COMPLETED NA

Contraceptive Counseling in the Postpartum Period

NCT02380781

COMPLETED

Sleep, Circadian Rhythm & Skin Health

NCT02457000

COMPLETED Phase 3

Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin

NCT03138252

COMPLETED Phase 2

Down Syndrome Memantine Follow-up Study

NCT02304302

COMPLETED NA

Music Therapy in Sickle Cell Pain Mixed Methods Study

NCT02270060

COMPLETED Phase 1

Injection With OnabotulinumtoxinA (Botox) for the Treatment of Chronic Pelvic Pain

NCT02173405

COMPLETED

Use of EndoPAT for Measurements of Endothelial Dysfunction in HIV Infected Children and Healthy Controls

NCT02324179

COMPLETED NA

Subsymptom Threshold Exercise Protocol Following Mild TBI

NCT02267668

COMPLETED NA

A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness

NCT02085447

COMPLETED

IL-17 Neutrophils in CF Lung Inflammation

NCT02025829

TERMINATED Phase 2

DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty

NCT01982760

COMPLETED Phase 1

Nebulized Hypertonic Saline for Mechanically Ventilated Children

NCT01945944

TERMINATED NA

Alzheimer's Disease Imaging With PET/MRI - Beta-amyloid

NCT02343757

COMPLETED NA

Laser Spot Treatment of Perioral Rhytids

NCT01986634

COMPLETED Phase 3

Effect of a One Time Dose of Cholecalciferol on Serum Concentration of 25-Hydroxyvitamin D and Macrophages

NCT02920502

TERMINATED NA

Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery

NCT01866657

TERMINATED Phase 1

Efficacy, Safety Study and Benefit of Alkali Therapy in Sickle Cell Disease

NCT01894594

COMPLETED

Comparative Effectiveness of Psoriasis Treatments on Systemic Inflammation

NCT02330380

COMPLETED

Infant Antibiotic Resistance and Implications for Therapeutic Decision-making

NCT01781182

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Phase Distribution

PhaseTrial count
Phase 1 14
Phase 2 13
Phase 3 16
Phase 4 32

Where University Hospitals Cleveland Medical Center enrollment is open (later-stage tilt)

42 recruiting of 230 indexed (18% open); 154 completed (67%).

Phase mix: 48 late (III/IV) vs 27 early (I/II) (later-stage heavy).

Top condition: Bipolar Disorder (6 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University Hospitals Cleveland Medical Center: open-pipeline peers nationwide

Peers matched on 230 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

University Hospitals Cleveland Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150200250 10%12%14%16%18%20% Total trials Recruiting share University Hospitals Cleveland Medical CenterBrown UniversityUniversity of IowaGeorgetown UniversityHenry Ford Health SystemBurke Medical Research InstituteGrand Valley State UniversityImunonInventisBio Co.
University Hospitals Cleveland Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University Hospitals Cleveland Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 230 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this University Hospitals Cleveland Medical Center page

230 registered trials is a research-attention snapshot, not an endorsement of University Hospitals Cleveland Medical Center or any single study.

  • 42 of University Hospitals Cleveland Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Bipolar Disorder is the condition University Hospitals Cleveland Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Bipolar Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

University Hospitals Cleveland Medical Center pipeline card: 230 registered trials from official public datasets.Report a data error.