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ClinicalTrials.gov 13 recruiting now official registry

Rotator Cuff Tears clinical trials

Every US clinical trial registered for Rotator Cuff Tears — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

21 US clinical trials · 13 currently recruiting

The research picture

Rotator Cuff Tears has 21 registered US clinical trials, 13 of them open to new participants right now — about 62% of the total.

13
recruiting participants now
62%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
2
top sponsor: University Hospitals Cleveland Medical Center

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 20,000 participants

Exactech Shoulder Post Market Clinical Follow-up Study

Exactech

NCT05603728

RECRUITING 3,500 participants

Genetic Epidemiology of Rotator Cuff Tears: The cuffGEN Study

University of Michigan

NCT04831164

RECRUITING NA 499 participants

Innovating Physical Therapy: A Pilot Study on Band Connect's Impact on Compliance, Satisfaction, and Revenue

University Hospitals Cleveland Medical Center

NCT06733480

RECRUITING NA 268 participants

BioBrace® Implant for Arthroscopic Repair of Full Thickness Rotator Cuff Tears

CONMED Corporation

NCT05997381

RECRUITING NA 160 participants

InSpace Accelerated Rehabilitation Study

Stryker Endoscopy

NCT05329584

RECRUITING NA 160 participants

RSA Vs RCR for Massive RCTs

La Tour Hospital

NCT05807854

RECRUITING NA 105 participants

Comparison of Partial Rotator Cuff Repair vs. Superior Capsular Reconstruction for Irreparable Rotator Cuff Tears

University Hospitals Cleveland Medical Center

NCT04742452

RECRUITING Phase 4 78 participants

Bioinductive Patch for Full-Thickness Rotator Cuff Tears

Henry Ford Health System

NCT05439850

RECRUITING NA 60 participants

FiberLocker® System Augmentation of Rotator Cuff Repairs

ZuriMED Technologies

NCT06918041

RECRUITING 60 participants

Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

Duke University

NCT04209504

RECRUITING NA 60 participants

Prospective Study to Determine the Safety and Effectiveness of a Connective Tissue Allograft Active Matrix (AM) vs. Standard of Care in Arthroscopic Rotator Cuff Repair

The University of Texas Health Science Center, Houston

NCT05894265

RECRUITING Phase 2 58 participants

Sex Hormone Supplementation and Rotator Cuff Repair: A Preliminary Randomized Trial

University of Utah

NCT04944836

RECRUITING Phase 1 40 participants

Tuberoplasty Versus Balloon Spacer

University of Minnesota

NCT06735170

ACTIVE NOT RECRUITING 200 participants

Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study

Stryker Trauma and Extremities

NCT05868148

ACTIVE NOT RECRUITING NA 91 participants

Rotator Cuff Healing Using a Nanofiber Scaffold in Patients Greater Than 55 Years

Atreon Orthopedics

NCT04325789

ACTIVE NOT RECRUITING Phase 3 65 participants

Use of Extended Release Triamcinolone in the Treatment of Rotator Cuff Disease

Northwell Health

NCT04094298

ACTIVE NOT RECRUITING 50 participants

Variation in Humeral Head Bone Marrow Characteristics With Rotator Cuff Repair Healing

The Cleveland Clinic

NCT05106088

ACTIVE NOT RECRUITING Phase 1 20 participants

Optimal Dosing of IC-Green for Visualization of Rotator Cuff Vascularity Using Advanced Imaging Modality Arthroscopy

NYU Langone Health

NCT04340752

ACTIVE NOT RECRUITING 20 participants

MRI Evaluation of Integrity Implant for Rotator Cuff Tears

Foundation for Orthopaedic Research and Education

NCT06353893

COMPLETED Phase 4 92 participants

Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair

Hospital for Special Surgery Florida

NCT04737980

COMPLETED 36 participants

Opioid-Free Study in Arthroscopic Rotator Cuff Repair

Rothman Institute Orthopaedics

NCT04277208

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 1
Phase 3 1
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Rotator Cuff Tears Trial Landscape

ClinicalTrials.gov lists 21 US studies indexed under Rotator Cuff Tears, and 13 of those are currently open to recruitment — roughly 62% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Rotator Cuff Tears shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Rotator Cuff Tears is led by University Hospitals Cleveland Medical Center with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 21 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Rotator Cuff Tears?

PlainTrial tracks 21 US clinical trials for Rotator Cuff Tears, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Rotator Cuff Tears?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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