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Peripheral Artery Disease: full-pipeline trial registry
28 of 51 indexed Peripheral Artery Disease trials are currently recruiting.
Corpus placement: #274 of 28,707 conditions by registered trial count.
51 US clinical trials · 28 currently recruiting · #274 of 28,707 conditions by registered trial count
Peripheral Artery Disease: 51 US clinical trials tracked, 28 recruiting.
Peripheral Artery Disease is the subject of 51 registered US clinical trials on ClinicalTrials.gov, 28 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Northwestern University, running 10 of these trials.
Enrollment posture brief
Registry condition peripheral-artery-disease
OPEN 28 | RECR 55% | LATE 6 | EARLY 9 | RANK #274 | SPON 10
Volume-matched condition peers
Nearest open-share peer: Head and Neck Carcinoma (55% recruiting · 31 trials)
Peripheral Artery Disease lists 28 open slots (55% of 51 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Peripheral Artery Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Peripheral Artery Disease is recruiting above its size-band peers.
28 of 51 indexed trials (54.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Peripheral Artery Disease research.
Northwestern University accounts for 10 of 51 trials (19.6%). 30 distinct sponsors appear on at least one study for this condition label.
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Typical Peripheral Artery Disease enrolment sits around 73 participants.
Median target enrolment is 73 among the 51 trials that report a genuine target (sentinel values excluded). 27 of those (52.9%) plan for fewer than 100 participants.
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Peripheral Artery Disease research is mostly interventional.
46 interventional and 5 observational studies make up this index (90.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
51 total, page 1 of 2
Vascular Lab Resource (VLR) Biorepository
The Cleveland Clinic
NCT05628948
Randomized Controlled Trial of Alert-Based Computerized Decision Support for Patients With Peripheral Artery Disease Not Prescribed Lipid-Lowering Therapy
Brigham and Women's Hospital
NCT06300450
Improving Mobility After Revascularization in Peripheral Artery Disease
Northwestern University
NCT06686121
Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee
Mercator MedSystems
NCT04433572
Intermittent Pneumatic Compression With and Without Exercise to Improve Functioning in Peripheral Artery Disease
Northwestern University
NCT03871075
Telehealth Delivered Home-based Walking for Vets With Peripheral Artery Disease
VA Office of Research and Development
NCT06033924
Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss
Northwestern University
NCT04228978
BEETroot Juice to Reverse Functional Impairment in PAD
Northwestern University
NCT05624125
Response to Exercise and Nitric Oxide in PAD
Northwestern University
NCT06657976
Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease
Nationwide Children's Hospital
NCT03622359
The COCOA-PAD II Trial
Northwestern University
NCT04794530
PRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG
Aventusoft
NCT06567795
The THOR IDE Study
Philips Clinical & Medical Affairs Global
NCT05916950
The Effects of Diet and Exercise Interventions in Peripheral Artery Disease
University of Oklahoma
NCT03845036
Leg Heat Therapy in Peripheral Artery Disease
Indiana University
NCT05465070
The Effects of a Novel, Non-ischemic and Pain-free Exercise Intervention in Peripheral Artery Disease
University of Oklahoma
NCT05712395
Exercise Therapy for PAD Using Mobile Health
VA Office of Research and Development
NCT04889105
Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation
VA Office of Research and Development
NCT03995238
Red Light Treatment in Peripheral Artery Disease
University of Alabama at Birmingham
NCT03203239
Far Red Light to Improve Functioning in PAD
Northwestern University
NCT06165016
ENhancing Exercise with LIGHT to Improve Functioning in PAD
Northwestern University
NCT06399900
Community-based Exercise Following Revascularization for PAD
University of Minnesota
NCT04252950
Mechanistic Clinical Trial of Colchicine in Patients With Peripheral Artery Disease
University of Pennsylvania
NCT06212271
Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease
University of Nebraska
NCT06389149
Passive Calf Stretching Therapy in Peripheral Artery Disease
Penn State University
NCT06041880
Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease
University of Nebraska
NCT06319339
Oxygen-guided Supervised Exercise Therapy
VA Office of Research and Development
NCT06003855
The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication
Louis Messina
NCT04800692
Disrupt PAD BTK II Study With the Shockwave Peripheral IVL System
Shockwave Medical
NCT05007925
Improve PAD PERformance With METformin
Northwestern University
NCT03054519
Telehealth to Improve Functional Status and Quality of Life in Veterans With PAD
VA Office of Research and Development
NCT05048979
Monitoring Local Tissue Oxygen Changes Using the Wireless Lumee Oxygen Platform in Correlation to TcPO2
Profusa
NCT04514861
RANGER™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty
Boston Scientific Corporation
NCT03064126
Low InTensity Exercise Intervention in PAD
Northwestern University
NCT02538900
Evaluation of Safety and Efficacy of the FlexStent® Femoropopliteal Self-Expanding Stent System
Cordis US
NCT01355406
BARD® Study of LIFESTREAM™ Balloon Expandable Covered Stent Treating Iliac Arterial Occlusive Disease
C. R. Bard
NCT02228564
Absolute Pro® MOMENTUM™
Abbott Medical Devices
NCT01444378
Implementation of Telemedicine for Patient With Lower Extremity Wounds
University of California, Davis
NCT04440839
Dysvascular Amputation Self-Management of Health
University of Colorado, Denver
NCT04083456
Imaging-Guided Vessel Sizing in the Tibial Arteries
University Hospitals Cleveland Medical Center
NCT04748965
A Cross-Sectional Study to Assess Walking Performance in Subjects With Peripheral Artery and End Stage Kidney Disease
Sanifit Therapeutics S. A.
NCT04487301
Exercise for Women With Peripheral Arterial Disease
University of Oklahoma
NCT01241747
Optical Imaging Measurement of Intravascular Solution Efficacy Trial
University Hospitals Cleveland Medical Center
NCT01743872
Using Smartphone Sensor Technology to Characterize Ambulatory Patterns of Participants With Peripheral Artery Disease
University of Minnesota
NCT04124315
Comparison of 2 Beta Blocker Drugs on Peripheral Arterial Disease in Patients With High Blood Pressure
Thomas Jefferson University
NCT01499134
Humacyte's HAV for Femoro-Popliteal Bypass in Patients With PAD
Humacyte
NCT02887859
Pilot Study of PRT-201 Following Angioplasty in Patients With Peripheral Artery Disease (PAD)
Proteon Therapeutics
NCT01616290
Dietary Nitrate Supplementation and Thermoregulation
University of Nebraska
NCT03506646
Assessment Of Vascular Health After Niacin Therapy (AVANT)
University of Pennsylvania
NCT02003638
NAD Supplementation and Vascular Health in PAD
University of Oklahoma
NCT06534944
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 3 |
| Phase 3 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on Peripheral Artery Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Peripheral Artery Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Peripheral Artery Disease page
51 registered trials, 28 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 28 Peripheral Artery Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Northwestern University sponsors the most Peripheral Artery Disease trials on record, review their full trial history before evaluating a specific study. See Northwestern University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Peripheral Artery Disease condition card totals 51 registered trials; most-linked intervention Exercise; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.