Takeda

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Takeda sits in the top decile of US sponsors by registered trial count (#88 of 15,742 sponsors by registered trial count).

408 total trials 49 currently recruiting 284 completed top decile by trial count

Takeda: 408 sponsored US clinical trials, 49 recruiting.

Takeda sponsors 408 registered US clinical trials on ClinicalTrials.gov, 49 of them currently recruiting, and 284 completed. 174 of these trials are in Phase 3-4 (later-stage) and 209 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy Volunteers, with 16 trials.

Top-decile sponsor footprint

Takeda ranks in the top decile of sponsors by registered trial count (#88 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 48/100

284 of 340 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

408 total, page 3 of 9

TERMINATED Phase 1

A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

NCT05070247

COMPLETED

A Study to Assess the Hypersensitivity to TAK-880 Compared to Gammagard S/D in Blood of Children, Teenagers and Adults

NCT05269082

COMPLETED Phase 1

A Study of Soticlestat Tablets in Healthy Adults

NCT05284760

TERMINATED Phase 3

A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

NCT05163314

TERMINATED Phase 1

A Study of TAK-951 in Participants With Cyclic Vomiting Syndrome (CVS)

NCT06768658

COMPLETED

Assessment of Updated Educational Materials for Instanyl®

NCT04938440

TERMINATED Phase 1

A Study of TAK-951 in Healthy Adults

NCT06610279

COMPLETED Phase 2

A Study to Evaluate the Efficacy, Safety, and Tolerability of NDI-034858 in Participants With Active Psoriatic Arthritis

NCT05153148

COMPLETED Phase 1

A Study of Relative Bioavailability of a New Formulation Compared With the Approved Formulation of rhPTH [1-84] and to Find Out Dose Linearity of the New Formulation in Healthy Adults

NCT05137730

COMPLETED Phase 3

A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome

NCT04938427

COMPLETED Phase 1

A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function

NCT05098054

COMPLETED Phase 3

A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome

NCT04940624

COMPLETED Phase 3

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis (UC)

NCT04779307

COMPLETED Phase 1

A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults

NCT05064449

COMPLETED Phase 1

A Study of TAK-881 in Healthy Adults

NCT05059977

COMPLETED

A Study to Evaluate Available Treatment Information of Ponatinib, Bosutinib, Imatinib, Dasatinib and Nilotinib in Adults With Chronic Myeloid Leukemia

NCT05743465

COMPLETED Phase 1

A Study of Danavorexton in Anesthetized Adults

NCT05025397

COMPLETED Phase 1

A Study of TAK-676 With Pembrolizumab After Radiation Therapy to Treat a Number of Cancers

NCT04879849

COMPLETED Phase 2

Study of NDI-034858 in Participants With Moderate to Severe Plaque Psoriasis

NCT04999839

COMPLETED Phase 1

A Study of TAK-105 in Healthy Adults

NCT04964258

TERMINATED Phase 3

A Study of Prucalopride For Functional Constipation in Children and Teenagers

NCT04759833

TERMINATED Phase 2

A Study of TAK-994 in Adults With Narcolepsy

NCT04820842

COMPLETED Phase 4

A Study of Enzyme Replacement Therapy (VPRIV) in People With Type 1 Gaucher Disease Who Were Previously Treated With Substrate Reduction Therapy

NCT04718779

TERMINATED Phase 1

A Study Of TAK-981 Given With Monoclonal Antibodies (mAbs) In Adults With Relapsed or Refractory Multiple Myeloma (RRMM)

NCT04776018

COMPLETED Phase 1

Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults

NCT04833049

TERMINATED Phase 1

A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer

NCT04844073

TERMINATED Phase 1

A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

NCT04501614

COMPLETED Phase 1

A Study of Different Forms of TAK-994 in Healthy Adults

NCT04745767

COMPLETED Phase 1

A Study of TAK-510 in Healthy Adults

NCT04731922

COMPLETED

A Study of Velaglucerase Alfa (VPRIV) Given as Standard Patient Care in Young Children With Gaucher Disease

NCT04721366

COMPLETED Phase 2

A Study of TAK-079 in Adults With Persistent/Chronic Primary Immune Thrombocytopenia

NCT04278924

COMPLETED Phase 2

A Study of TAK-071 in People With Parkinson Disease

NCT04334317

COMPLETED Phase 2

A Study of TAK-951 to Stop Adults Getting Nausea and Vomiting After Planned Surgery

NCT04557189

COMPLETED Phase 2

A Study of Pevonedistat and Venetoclax Combined With Azacitidine to Treat Acute Myeloid Leukemia (AML) in Adults Unable to Receive Intensive Chemotherapy

NCT04266795

COMPLETED Phase 1

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics (PK) of Oral TAK-994 in an Acute Sleep Phase Delay Paradigm in Healthy Male Participants

NCT04551079

COMPLETED Phase 1

A Study of TAK-981 Given With Pembrolizumab in Participants With Select Advanced or Metastatic Solid Tumors

NCT04381650

COMPLETED

Drug Use Study of Febuxostat After Recent Changes in the Prescribing Information

NCT04853160

COMPLETED Phase 1

A Study to Determine the Safety, Tolerability, and Pharmacokinetics of Lanadelumab Administered Intravenously in Healthy Adult Volunteer Participants

NCT04503603

TERMINATED Phase 2

A Study of TAK-018 in Preventing the Recurrence of Crohn's Disease After Surgery

NCT03943446

COMPLETED

Wake and Sleep State Transitions on a Portable Electroencephalogram (EEG) Device in Narcolepsy Type 1 (NT1) and Healthy Participants

NCT04445129

COMPLETED Phase 1

Study to Assess Absolute Bioavailability of TAK-935 (OV935) and to Characterize Mass Balance, Pharmacokinetics, Metabolism, and Excretion of [14C]TAK-935 (OV935) in Healthy Male Participants

NCT04992442

COMPLETED Phase 1

A Study of TAK-951 in Healthy Adults

NCT04486950

COMPLETED Phase 1

A Study to Evaluate the Effect of High-Fat Meal on TAK-788 Pharmacokinetics (PK) in Healthy Adult Participants

NCT04441255

TERMINATED Phase 2

A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy

NCT04096560

COMPLETED Phase 3

A Study of Lanadelumab in Teenagers and Adults to Prevent Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH)

NCT04206605

COMPLETED Phase 2

A Study of TAK-079 in People With Generalized Myasthenia Gravis

NCT04159805

TERMINATED Phase 1

A Study With [18F]MNI-1054 to Determine Lysine -Specific Demethylase 1A (LSD1) Brain Enzyme Occupancy of TAK-418 After Single-Dose Oral Administration in Healthy Participants

NCT04202497

COMPLETED Phase 3

Long-Term Safety and Antibody Persistence of TDV and the Impact of a Booster Dose

NCT03999996

COMPLETED Phase 3

Long-term Follow-up Study With Darvadstrocel in the Treatment of Complex Perianal Fistula

NCT04075825

TERMINATED Phase 1

A Study of TAK-981 Given With Rituximab in Adults With Relapsed or Refractory CD20-Positive Non-Hodgkin Lymphoma

NCT04074330

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What is open in the Takeda pipeline

49 recruiting of 408 indexed (12% open); 284 completed (70%).

Phase mix: 174 late (III/IV) vs 209 early (I/II) (balanced across stages).

Top condition: Healthy Volunteers (16 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Takeda: open-pipeline peers nationwide

Peers matched on 408 registered trials and 12% open enrollment, not the therapeutic-area sidebar.

Takeda sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 10%15%20%25% Total trials Recruiting share TakedaUniversity of Kansas Medical CenterCase Comprehensive Cancer CenterUniversity of NebraskaSt. Jude Children's Research HospitalArcus BiosciencesArdelyxKyowa Kirin Co.East Carolina University
Takeda sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Takeda sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 408 trials (± recruiting share)

Sponsors near 12% open enrollment (± trial volume)

What to do with this Takeda page

408 registered trials is a research-attention snapshot, not an endorsement of Takeda or any single study.

  • 49 of Takeda's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy Volunteers is the condition Takeda studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy Volunteers trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Takeda pipeline card: 408 registered trials from official public datasets.Report a data error.