Kyowa Kirin Co.

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Kyowa Kirin Co. sits in the top decile of US sponsors by registered trial count (#626 of 15,742 sponsors by registered trial count).

25 total trials 3 currently recruiting 15 completed early-phase tilt top decile by trial count

Kyowa Kirin Co.: 25 sponsored US clinical trials, 3 recruiting.

Kyowa Kirin Co. sponsors 25 registered US clinical trials on ClinicalTrials.gov, 3 of them currently recruiting, and 15 completed. 4 of these trials are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is X-linked Hypophosphatemia, with 2 trials.

Top-decile sponsor footprint

Kyowa Kirin Co. ranks in the top decile of sponsors by registered trial count (#626 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 27/100

15 of 20 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (75.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

25 total, page 1 of 1

RECRUITING Phase 1

A Phase 1/2 Study of KK2430 in Participants With Hematologic Neoplasms

NCT07629726

RECRUITING Phase 1

A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia

NCT06525636

RECRUITING Phase 1

A Study of KK2269 in Adult Participants With Solid Tumors

NCT06266299

ACTIVE NOT RECRUITING Phase 2

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration

NCT06116890

ACTIVE NOT RECRUITING Phase 2

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema

NCT06116916

COMPLETED Phase 1

A Study to Evaluate Abuse Potential of Istradefylline

NCT02609477

COMPLETED Phase 3

Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease

NCT02610231

COMPLETED Phase 1

Effect of Mild Hepatic Impairment on the Pharmacokinetics of Istradefylline

NCT02256033

COMPLETED Phase 1

The Effect of Rifampin on the Metabolism of Istradefylline in Healthy Volunteers.

NCT02174250

COMPLETED Phase 3

A 12-week Randomized Study to Evaluate Oral Istradefylline in Subjects With Moderate to Severe Parkinson's Disease

NCT01968031

COMPLETED Phase 1

An Extension Study of KRN23 in Adults With X-Linked Hypophosphatemia

NCT01571596

COMPLETED Phase 1

A Repeated Study of KRN23 in Adults With X-Linked Hypophosphatemia

NCT01340482

TERMINATED Phase 1

Study of Anti-HB-EGF Antibody KHK2866 in Subjects With Advanced Solid Tumors and Ovarian Cancer

NCT01279291

TERMINATED Phase 1

Safety, Tolerability, and Efficacy Study in Subjects With Advanced or Metastatic Breast Cancer

NCT01199367

COMPLETED Phase 2

Extension Study in Subjects Who Relapsed After Complete Response on Study KW-0761-001

NCT01226472

COMPLETED Phase 1

A Study of KW-2478 in Combination With Bortezomib in Subjects With Relapsed and/or Refractory Multiple Myeloma

NCT01063907

COMPLETED Phase 1

Safety Study to Evaluate KW-2450 in Subjects With Advanced Solid Tumor

NCT00921336

COMPLETED Phase 1

Safety Study to Evaluate Monoclonal Antibody KW-0761 in Subjects With Peripheral T-cell Lymphoma

NCT00888927

COMPLETED Phase 1

Safety Study of Electrocardiogram (ECG) Effects of Sancuso® (Granisetron TDS)

NCT00890565

TERMINATED Phase 1

Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer

NCT00838578

TERMINATED Phase 1

Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Study of KW-2449 in Acute Myelogenous Leukemia (AML) (Protocol Number: 2449-US-002)

NCT00779480

COMPLETED Phase 1

A Study of KRN23 in X-linked Hypophosphatemia

NCT00830674

TERMINATED Phase 1

Phase 1/2 Study of Anti GM-2 Monoclonal Antibody To Treat Multiple Myeloma

NCT00775502

COMPLETED Phase 3

Efficacy and Safety of Sublingual Fentanyl Tablets in Treatment of Breakthrough Pain in Cancer Patients.

NCT00262678

COMPLETED Phase 3

Long-term Safety Study of Sublingual Fentanyl Tablets in Cancer Patients

NCT00263575

What is open in the Kyowa Kirin Co. pipeline

3 recruiting of 25 indexed (12% open); 15 completed (60%).

Phase mix: 4 late (III/IV) vs 21 early (I/II) (early-phase heavy).

Top condition: X-linked Hypophosphatemia (2 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Kyowa Kirin Co.: open-pipeline peers nationwide

Peers matched on 25 registered trials and 12% open enrollment, not the therapeutic-area sidebar.

Kyowa Kirin Co. sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 0%5%10%15% Total trials Recruiting share Kyowa Kirin Co.Arcus BiosciencesArcutis BiotherapeuticsArdelyxDrexel University College of MedicineTakedaEast Carolina UniversityNational Institute of Dental and Craniofacial Research (NIDCR)Antonios Likourezos
Kyowa Kirin Co. sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Kyowa Kirin Co. sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 25 trials (± recruiting share)

Sponsors near 12% open enrollment (± trial volume)

What to do with this Kyowa Kirin Co. page

25 registered trials is a research-attention snapshot, not an endorsement of Kyowa Kirin Co. or any single study.

  • 3 of Kyowa Kirin Co.'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • X-linked Hypophosphatemia is the condition Kyowa Kirin Co. studies most, compare against other sponsors active in the same condition before evaluating a specific study. See X-linked Hypophosphatemia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Kyowa Kirin Co. pipeline card: 25 registered trials from official public datasets.Report a data error.