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NCT05064449 · ClinicalTrials.gov registry record · Phase 1

A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults

A Phase 1 study, sponsored by Takeda.

Completed
Registry status
Phase 1
Development phase
28
Enrollment target

NCT05064449 is a Phase 1 study that has completed, run by Takeda. The registered enrollment target is 28 participants.

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The verdict

NCT05064449, a Phase 1 study, has completed, sponsored by Takeda.

COMPLETED
Registry status
Phase 1
Development phase
28 participants
Enrollment target

Study Summary

The main aim of this study is to check how itraconazole and mefenamic acid affect the way soticlestat is processed by the body. The study will have 2 parts. Participants can only participate in one study part. Part 1: Participants will check into the study clinic to receive soticlestat, four days later they will begin receiving itraconazole and will stay in the clinic for 11 more days, receiving soticlestat in combination with itraconazole on one of those days. Participants will be contacted about 8 days after leaving the clinic for follow-up. Part 2: Participants will check into the study clinic to receive soticlestat, four days later they will begin receiving mefenamic acid and will stay in the clinic for 7 more days, receiving soticlestat in combination with mefenamic acid on one of those days.. Participants will be contacted about 9 days after leaving the clinic for follow-up.

Interventions

  • DRUG Itraconazole
  • DRUG Soticlestat
  • DRUG Mefenamic acid

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2021-10-14
Est. Completion 2021-11-30
Phase Phase 1

Sponsor

Takeda

408 total trials

What the Registry Record Tells You About NCT05064449

The ClinicalTrials.gov registry entry for NCT05064449 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Takeda, which has 408 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Itraconazole is the first listed.

NCT05064449 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05064449 about?

NCT05064449 is a clinical study titled "A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults". The main aim of this study is to check how itraconazole and mefenamic acid affect the way soticlestat is processed by the body. The study will have 2 parts. Participants can only participate in one study part. Part 1: Participants will check into the study clinic to receive soticlestat, four days ...

What is the current status of trial NCT05064449?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2021-10-14. Estimated completion is 2021-11-30.

What interventions are being tested in trial NCT05064449?

The interventions under investigation include: Itraconazole (DRUG), Soticlestat (DRUG), Mefenamic acid (DRUG).

Who is sponsoring clinical trial NCT05064449?

This trial is sponsored by Takeda, which has 408 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.