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NCT01653834 · ClinicalTrials.gov registry record · NA

Feasibility of Lymphocyte Reinfusion in Newly Diagnosed High Grade Gliomas

A NA study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
NA
Development phase
10
Enrollment target

NCT01653834: Completed NA study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

NCT01653834 is a NA study that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01653834, a NA study, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target

Study Summary

This research study is being done to see if lymphocytes can be collected from patients with high grade gliomas before they start standard radiation and chemotherapy. (Lymphocytes are cells that normally circulate in the blood and are an essential part of the immune system). The investigators goal is to store these and give them back to the patient after radiation is completed. This is part of a larger effort that will attempt to preserve the immune system from the effects of radiation and chemotherapy.

Primary Outcome

this will be considered a feasible approach if 5 of the 10 patients to be accrued have an absolute lymphocyte count increase of 300 cells per mm3 at 4 weeks after reinfusion.

Interventions

  • PROCEDURE Lymphocyte harvesting & reinfusion

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2012-07
Est. Completion 2014-03
Phase NA

What the finished NCT01653834 record still lists

NCT01653834 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Lymphocyte harvesting & reinfusion is the first listed.

NCT01653834 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01653834 about?

NCT01653834 is a clinical study titled "Feasibility of Lymphocyte Reinfusion in Newly Diagnosed High Grade Gliomas". This research study is being done to see if lymphocytes can be collected from patients with high grade gliomas before they start standard radiation and chemotherapy. (Lymphocytes are cells that normally circulate in the blood and are an essential part of the immune system). The investigators goal is...

What is the current status of trial NCT01653834?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2012-07. Estimated completion is 2014-03.

What interventions are being tested in trial NCT01653834?

The interventions under investigation include: Lymphocyte harvesting & reinfusion (PROCEDURE).

Who is sponsoring clinical trial NCT01653834?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01653834's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01653834, the US trial registry maintained by the National Library of Medicine. NCT01653834 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.