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NCT01862731 · ClinicalTrials.gov registry record
Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain
A clinical trial of Patellofemoral Pain Syndrome, sponsored by National Institutes of Health Clinical Center (CC).
- Completed
- Registry status
- 35
- Enrollment target
- 1
- Study location
NCT01862731: Completed study of Patellofemoral Pain Syndrome, sponsored by National Institutes of Health Clinical Center (CC).
NCT01862731 is a study of Patellofemoral Pain Syndrome that has completed, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 35 participants, below the 143-participant average among 10 other Patellofemoral Pain Syndrome trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01862731, a study of Patellofemoral Pain Syndrome, has completed, sponsored by National Institutes of Health Clinical Center (CC).
- COMPLETED
- Registry status
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: \- Researchers are interested in how the muscles affect the movement of the knee cap. These muscles may be related to different kinds of knee pain that are not caused by an injury or a disease. Imaging studies such as magnetic resonance imaging (MRI) can be used to look at these muscles. To study these muscles and how they move, researchers will use MRI to look at healthy individuals and individuals with knee cap pain. Objectives: \- To study how changes to the muscles around the knee can influence knee pain. Eligibility: * Individuals between 18 to 55 years of age who have knee cap pain that cannot be explained by a specific injury or disease. * Healthy volunteers between 18 and 55 years of age. Design: * Participants will be screened with a physical exam and medical history. * This study requires two visits. Each visit will use standard MRI sequences to take images of the knee in motion and at rest. * On the first visit, the MRI scan will look at the knee in its natural state. Participants will move the knee up and down for 1 to 3 minutes at a time during the scan. * On the second visit, a local anesthetic agent will be injected into the muscle of the thigh. The anesthetic will block this muscle from generating force for 2 or 3 hours. Participants will move the knee up and down for 1 to 3 minutes at a time during the MRI scan.
Primary Outcome
The change in patellofemoral kinematics, patellofemoral pain, and quadriceps strength pre- and post-muscle block.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2013-05-31 |
What the finished NCT01862731 record still lists
NCT01862731 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 143-participant average among 10 other Patellofemoral Pain Syndrome trials with a reported enrollment target (76% lower).
The record links to 1 condition, with Patellofemoral Pain Syndrome appearing as the primary indexed condition, and to 0 interventions.
NCT01862731 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT01862731 about?
NCT01862731 is a clinical study titled "Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain". Background: \- Researchers are interested in how the muscles affect the movement of the knee cap. These muscles may be related to different kinds of knee pain that are not caused by an injury or a disease. Imaging studies such as magnetic resonance imaging (MRI) can be used to look at these muscles...
What is the current status of trial NCT01862731?
This trial is currently completed. The enrollment target is 35 participants. The study started on 2013-05-31.
What conditions does trial NCT01862731 study?
This clinical trial studies the following conditions: Patellofemoral Pain Syndrome.
Who is sponsoring clinical trial NCT01862731?
This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01862731 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01862731's enrollment target sits among peer trials
35 9th of 10 higher than 2 of 10 other Patellofemoral Pain Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Patellofemoral Pain Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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