National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute on Alcohol Abuse and Alcoholism (NIAAA) sits in the top decile of US sponsors by registered trial count (#253 of 15,742 sponsors by registered trial count).

93 total trials 16 currently recruiting 71 completed early-phase tilt top decile by trial count

National Institute on Alcohol Abuse and Alcoholism (NIAAA): 93 sponsored US clinical trials, 16 recruiting.

National Institute on Alcohol Abuse and Alcoholism (NIAAA) sponsors 93 registered US clinical trials on ClinicalTrials.gov, 16 of them currently recruiting, and 71 completed. 9 of these trials are in Phase 3-4 (later-stage) and 58 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Alcoholism, with 11 trials.

Top-decile sponsor footprint

National Institute on Alcohol Abuse and Alcoholism (NIAAA) ranks in the top decile of sponsors by registered trial count (#253 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 70/100

71 of 77 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (92.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

93 total, page 2 of 2

COMPLETED Phase 1

Computer-Assisted Self-Administration of Ethanol

NCT00713492

COMPLETED Early Phase 1

The Effect of Naltrexone on Alcohol Craving and on Brain Activity During Alcohol Infusion

NCT00667771

COMPLETED Phase 2

Modulation of Pharmacologically Induced Alcohol Craving in Recently Detoxified Alcoholics

NCT00605904

COMPLETED Phase 2

Study of the Effectiveness of Quetiapine for the Treatment of Alcohol Dependency

NCT00498628

COMPLETED Phase 2

Aripiprazole and Topiramate on Free-Choice Alcohol Use

NCT00884884

COMPLETED

OPRM1 A118G SNP, Alcohol Response, and Striatal Dopamine

NCT00401999

COMPLETED Phase 1

Stepped Care for Mandated College Students

NCT00247182

COMPLETED NA

Psychoeducation for Hepatitis and Alcohol Behaviors

NCT00598416

COMPLETED Phase 3

Medication and Counseling for Controlled Drinking (Project SMART)

NCT00444418

COMPLETED Phase 2

Effect of LY686017 on Alcohol Craving

NCT00310427

COMPLETED Phase 1

Individualized Treatment Program for Alcohol Problems

NCT00298792

COMPLETED Phase 4

Treatment of Patients With Alcoholism and Attention Deficit Disorder

NCT00261872

COMPLETED Phase 2

Aftercare for Adolescents Treated for Alcohol Abuse and Dependence

NCT00561041

COMPLETED

Alcoholism Assessment and Treatment

NCT00106093

COMPLETED Phase 2

Rimonabant to Reduce Alcohol Consumption

NCT00075205

COMPLETED

PET Imaging of DHA Metabolism

NCT00074503

COMPLETED

The Effect of Ethanol on Brain Activity

NCT00074360

COMPLETED

Influence of Age and Sex on Alcohol Metabolism and Acute Responses

NCT00070577

COMPLETED Phase 2

Hangover, Congeners, Sleep and Occupational Performance

NCT00247585

COMPLETED Phase 2

Healthy Living as You Age

NCT00379093

COMPLETED

Blood Sample Donations to Study the Role of Genes in Pain

NCT00341367

COMPLETED Phase 2

A Placebo-Controlled Trial of Memantine for Alcohol Dependence

NCT00246415

COMPLETED

Role of Dopamine in Response to Alcohol

NCT00050219

COMPLETED

Brain Function in Response to Motivational Stimuli

NCT00047866

COMPLETED Phase 4

Bupropion as a Smoking Cessation Aid in Alcoholics

NCT00044434

COMPLETED Phase 2

Combined Pharmacotherapies for Alcoholism (Naltrexone/Ondansetron)

NCT00027079

COMPLETED Phase 2

Comparing the Treatment of Alcohol Withdrawal Syndrome Using Gabapentin Versus Lorazepam

NCT00229125

COMPLETED Phase 1

Effect of Polyunsaturated Fatty Acids on Cardiovascular and Motor Responses Under Stress

NCT00014027

COMPLETED Phase 2

Effect of Fluoxetine (Prozac) on Domestic Violence

NCT00011765

COMPLETED

Serotonin in Alcoholism

NCT00011752

COMPLETED Phase 2

Drug Treatment for Alcoholics With Bipolar Disorder

NCT00000439

COMPLETED Phase 4

Drug Treatment for Depressed Alcoholics (Naltrexone/Fluoxetine)

NCT00006204

COMPLETED

The Effect of Positive and Negative Emotions on Brain Activity in Alcoholics and Nonalcoholics

NCT00001675

COMPLETED

Screening Evaluation for Studies of the National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT00001673

COMPLETED Phase 2

Ondansetron Treatment for Alcoholism

NCT00000443

COMPLETED Phase 2

Sertraline and Cognitive Therapy in Depressed Alcoholics

NCT00000458

COMPLETED Phase 4

Drug Therapy for Alcohol Detoxification

NCT00000441

COMPLETED Phase 2

Sertraline and Naltrexone for Alcohol Dependence

NCT00000440

COMPLETED Phase 2

Drug Treatment for Alcoholics With Post-Traumatic Stress Disorder

NCT00000446

COMPLETED Phase 2

Comparing Gabapentin and Lorazepam for Treating Alcohol Withdrawal

NCT00011297

COMPLETED Phase 4

Naltrexone Treatment of Alcohol Dependence

NCT00000452

COMPLETED Phase 4

Behavior and Naltrexone Treatment for Alcoholics

NCT00000449

COMPLETED Phase 4

Use of Naltrexone in a Clinical Setting

NCT00000445

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Phase Distribution

PhaseTrial count
Phase 1 21
Phase 2 37
Phase 3 1
Phase 4 8

What is open in the National Institute on Alcohol Abuse and Alcoholism (NIAAA) pipeline

16 recruiting of 93 indexed (17% open); 71 completed (76%).

Phase mix: 9 late (III/IV) vs 58 early (I/II) (early-phase heavy).

Top condition: Alcoholism (11 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute on Alcohol Abuse and Alcoholism (NIAAA): open-pipeline peers nationwide

Peers matched on 93 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

National Institute on Alcohol Abuse and Alcoholism (NIAAA) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15%20%25% Total trials Recruiting share National Institute on Alcohol Abuse and Alcoholism (NIAAA)National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)Roxane LaboratoriesColorado State UniversityEndeavor HealthEmory UniversityBaylor Research InstituteHunter College of City University of New YorkOchsner Health System
National Institute on Alcohol Abuse and Alcoholism (NIAAA) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute on Alcohol Abuse and Alcoholism (NIAAA) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 93 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this National Institute on Alcohol Abuse and Alcoholism (NIAAA) page

93 registered trials is a research-attention snapshot, not an endorsement of National Institute on Alcohol Abuse and Alcoholism (NIAAA) or any single study.

  • 16 of National Institute on Alcohol Abuse and Alcoholism (NIAAA)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Alcoholism is the condition National Institute on Alcohol Abuse and Alcoholism (NIAAA) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Alcoholism trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

National Institute on Alcohol Abuse and Alcoholism (NIAAA) pipeline card: 93 registered trials from official public datasets.Report a data error.