National Institute on Alcohol Abuse and Alcoholism (NIAAA)

93 total trials 16 currently recruiting 71 completed

National Institute on Alcohol Abuse and Alcoholism (NIAAA) sponsors 93 registered US clinical trials on ClinicalTrials.gov, 16 of them currently recruiting, and 71 completed. 9 of these trials are in Phase 3-4 (later-stage) and 58 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Alcoholism, with 11 trials.

Trial Pipeline

93 total, page 2 of 2

COMPLETED Phase 1

Computer-Assisted Self-Administration of Ethanol

NCT00713492

COMPLETED Early Phase 1

The Effect of Naltrexone on Alcohol Craving and on Brain Activity During Alcohol Infusion

NCT00667771

COMPLETED Phase 2

Modulation of Pharmacologically Induced Alcohol Craving in Recently Detoxified Alcoholics

NCT00605904

COMPLETED Phase 2

Study of the Effectiveness of Quetiapine for the Treatment of Alcohol Dependency

NCT00498628

COMPLETED Phase 2

Aripiprazole and Topiramate on Free-Choice Alcohol Use

NCT00884884

COMPLETED

OPRM1 A118G SNP, Alcohol Response, and Striatal Dopamine

NCT00401999

COMPLETED Phase 1

Stepped Care for Mandated College Students

NCT00247182

COMPLETED NA

Psychoeducation for Hepatitis and Alcohol Behaviors

NCT00598416

COMPLETED Phase 3

Medication and Counseling for Controlled Drinking (Project SMART)

NCT00444418

COMPLETED Phase 2

Effect of LY686017 on Alcohol Craving

NCT00310427

COMPLETED Phase 1

Individualized Treatment Program for Alcohol Problems

NCT00298792

COMPLETED Phase 4

Treatment of Patients With Alcoholism and Attention Deficit Disorder

NCT00261872

COMPLETED Phase 2

Aftercare for Adolescents Treated for Alcohol Abuse and Dependence

NCT00561041

COMPLETED

Alcoholism Assessment and Treatment

NCT00106093

COMPLETED Phase 2

Rimonabant to Reduce Alcohol Consumption

NCT00075205

COMPLETED

PET Imaging of DHA Metabolism

NCT00074503

COMPLETED

The Effect of Ethanol on Brain Activity

NCT00074360

COMPLETED

Influence of Age and Sex on Alcohol Metabolism and Acute Responses

NCT00070577

COMPLETED Phase 2

Hangover, Congeners, Sleep and Occupational Performance

NCT00247585

COMPLETED Phase 2

Healthy Living as You Age

NCT00379093

COMPLETED

Blood Sample Donations to Study the Role of Genes in Pain

NCT00341367

COMPLETED Phase 2

A Placebo-Controlled Trial of Memantine for Alcohol Dependence

NCT00246415

COMPLETED

Role of Dopamine in Response to Alcohol

NCT00050219

COMPLETED

Brain Function in Response to Motivational Stimuli

NCT00047866

COMPLETED Phase 4

Bupropion as a Smoking Cessation Aid in Alcoholics

NCT00044434

COMPLETED Phase 2

Combined Pharmacotherapies for Alcoholism (Naltrexone/Ondansetron)

NCT00027079

COMPLETED Phase 2

Comparing the Treatment of Alcohol Withdrawal Syndrome Using Gabapentin Versus Lorazepam

NCT00229125

COMPLETED Phase 1

Effect of Polyunsaturated Fatty Acids on Cardiovascular and Motor Responses Under Stress

NCT00014027

COMPLETED Phase 2

Effect of Fluoxetine (Prozac) on Domestic Violence

NCT00011765

COMPLETED

Serotonin in Alcoholism

NCT00011752

COMPLETED Phase 2

Drug Treatment for Alcoholics With Bipolar Disorder

NCT00000439

COMPLETED Phase 4

Drug Treatment for Depressed Alcoholics (Naltrexone/Fluoxetine)

NCT00006204

COMPLETED

The Effect of Positive and Negative Emotions on Brain Activity in Alcoholics and Nonalcoholics

NCT00001675

COMPLETED

Screening Evaluation for Studies of the National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT00001673

COMPLETED Phase 2

Ondansetron Treatment for Alcoholism

NCT00000443

COMPLETED Phase 2

Sertraline and Cognitive Therapy in Depressed Alcoholics

NCT00000458

COMPLETED Phase 4

Drug Therapy for Alcohol Detoxification

NCT00000441

COMPLETED Phase 2

Sertraline and Naltrexone for Alcohol Dependence

NCT00000440

COMPLETED Phase 2

Drug Treatment for Alcoholics With Post-Traumatic Stress Disorder

NCT00000446

COMPLETED Phase 2

Comparing Gabapentin and Lorazepam for Treating Alcohol Withdrawal

NCT00011297

COMPLETED Phase 4

Naltrexone Treatment of Alcohol Dependence

NCT00000452

COMPLETED Phase 4

Behavior and Naltrexone Treatment for Alcoholics

NCT00000449

COMPLETED Phase 4

Use of Naltrexone in a Clinical Setting

NCT00000445

← Previous Page 2 of 2

Phase Distribution

PhaseTrial count
Phase 1 21
Phase 2 37
Phase 3 1
Phase 4 8

What the Pipeline for National Institute on Alcohol Abuse and Alcoholism (NIAAA) Shows

According to the ClinicalTrials.gov registry, National Institute on Alcohol Abuse and Alcoholism (NIAAA) is linked to 93 US clinical trials across every stage of research activity. Of those, 16 studies are currently recruiting, about 17% of the sponsor's indexed portfolio, and 71 are already marked complete, representing roughly 76% of the total.

The phase mix for National Institute on Alcohol Abuse and Alcoholism (NIAAA) reports 9 late-stage studies (Phase 3 and Phase 4 combined) and 58 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute on Alcohol Abuse and Alcoholism (NIAAA) is Alcoholism with 11 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.