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NCT00000458 · ClinicalTrials.gov registry record · Phase 2
Sertraline and Cognitive Therapy in Depressed Alcoholics
A Phase 2 study, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
- Completed
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
NCT00000458: Completed Phase 2 study, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
NCT00000458 is a Phase 2 study that has completed, run by National Institute on Alcohol Abuse and Alcoholism (NIAAA). The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00000458, a Phase 2 study, has completed, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
Study Summary
This study will assess whether individuals treated with sertraline (Zoloft) and cognitive behavior therapy will experience improvement with their depression and consume less alcohol than individuals treated with a placebo and cognitive behavior therapy. This is a 12-week, random assignment, placebo-controlled, double-blind study with followup assessments 1 and 3 months after treatment.
Interventions
- BEHAVIORAL cognitive behavior therapy
- DRUG sertraline (Zoloft)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Est. Completion | 2002-01 |
| Phase | Phase 2 |
What the finished NCT00000458 record still lists
NCT00000458 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 2 interventions - of which cognitive behavior therapy is the first listed.
NCT00000458 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00000458 about?
NCT00000458 is a clinical study titled "Sertraline and Cognitive Therapy in Depressed Alcoholics". This study will assess whether individuals treated with sertraline (Zoloft) and cognitive behavior therapy will experience improvement with their depression and consume less alcohol than individuals treated with a placebo and cognitive behavior therapy. This is a 12-week, random assignment, placebo-...
What is the current status of trial NCT00000458?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 100 participants. Estimated completion is 2002-01.
What interventions are being tested in trial NCT00000458?
The interventions under investigation include: cognitive behavior therapy (BEHAVIORAL), sertraline (Zoloft) (DRUG).
Who is sponsoring clinical trial NCT00000458?
This trial is sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA), which has 93 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00000458's enrollment target sits among peer trials
100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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