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NCT00059033 · ClinicalTrials.gov registry record
Evaluation of Primary Chronic Autonomic Failure
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Terminated
- Registry status
- 325
- Enrollment target
NCT00059033: Clinical Trial study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00059033 is a clinical trial that was terminated before completion, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 325 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00059033 was terminated before completion, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- TERMINATED
- Registry status
- 325 participants
- Enrollment target
Study Summary
This study will conduct tests in patients with primary chronic autonomic failure (CAF) to learn more about these disorders, which include pure autonomic failure, multiple system atrophy, Parkinson's disease with autonomic failure, and autoimmune autonomic neuropathy. Healthy volunteers and patients with primary CAF 18 years of age or older may be eligible for this study. Participants undergo some of the following tests: * Blood studies, including arterial catheter insertion to measure blood pressure and collect arterial blood samples, blood flow studies using sensors applied to the skin and a pressure cuff around a limb, and blood draw for genetic studies. * Bladder motility: Ultrasound test of bladder function. * Electrocardiogram and heart ultrasound. * Responses to changes in temperature: Warm water and then room temperature water are passed through watertight pads applied to the back and front of the body and body temperatures are measured. * Gastrointestinal motility: Bowel sounds are recorded using a microphone placed on the abdomen. * Lower body negative pressure: The lower body is placed into an airtight barrel-like chamber. Some air is sucked out of the barrel, causing blood to pool in the legs, as occurs during standing. * Lumbar puncture: A needle is inserted in the space between the bones in the lower back to collect a small sample of cerebrospinal fluid. * Microdialysis to measures levels of chemicals in the body fluid of certain tissues. A solution is passed through a thin tube inserted into the skin. Chemicals in the body tissues enter the solution. The solution is collected and the chemical levels are measured. * PET scanning: A nuclear medicine test to produce images of body organs. For patients with urinary problems, a catheter is inserted into the bladder before starting the scan. * Pupillometry: The pupil of the eye is measured using a special camera in a light-controlled room. * QSART. A small amount of a brain chemical is applied to the skin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 325 participants |
| Start Date | 2003-04-10 |
| Est. Completion | 2018-10-30 |
Why NCT00059033 stopped before completion
NCT00059033 is an observational study that tracks outcomes without assigning an intervention. The registered 325 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00059033 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00059033 about?
NCT00059033 is a clinical study titled "Evaluation of Primary Chronic Autonomic Failure". This study will conduct tests in patients with primary chronic autonomic failure (CAF) to learn more about these disorders, which include pure autonomic failure, multiple system atrophy, Parkinson's disease with autonomic failure, and autoimmune autonomic neuropathy. Healthy volunteers and patients...
What is the current status of trial NCT00059033?
This trial is currently terminated. The enrollment target is 325 participants. The study started on 2003-04-10. Estimated completion is 2018-10-30.
Who is sponsoring clinical trial NCT00059033?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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