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NCT01524549 · ClinicalTrials.gov registry record
Blood Vessel Study
A clinical trial of Cardiovascular Disease, sponsored by National Institute of Environmental Health Sciences (NIEHS).
- Completed
- Registry status
- 178
- Enrollment target
- 1
- Study location
NCT01524549: Completed study of Cardiovascular Disease, sponsored by National Institute of Environmental Health Sciences (NIEHS).
NCT01524549 is a study of Cardiovascular Disease that has completed, run by National Institute of Environmental Health Sciences (NIEHS). The registered enrollment target is 178 participants, below the 2,696-participant average among 137 other Cardiovascular Disease trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01524549, a study of Cardiovascular Disease, has completed, sponsored by National Institute of Environmental Health Sciences (NIEHS).
- COMPLETED
- Registry status
- 178 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: \- The endothelium is the inner lining of blood vessels. The cells in this lining help regulate blood flow and immune system function. Problems with endothelial cells can contribute to heart disease, high blood pressure, and diabetes. Certain genes or parts of genes may be related to problems with endothelial function. Researchers want to study healthy adults who have genes that may affect their endothelial function. More information on these genes may provide more information on genetic risk for certain diseases. Objectives: \- To study healthy adults who have genetic markers related to endothelial cell problems. Eligibility: * Healthy volunteers between 18 and 65 years of age. * Current participants of the Environmental Polymorphisms Registry and have certain genes related to endothelial cell problems. Design: * Participants will have a single study visit to collect information and samples. * Participants will be screened with a physical exam and medical history. Blood and urine samples will be collected. * Participants will have an ultrasound of the artery in the arm and will be given a short-acting medication called nitroglycerin to study blood flow and blood pressure....
Primary Outcome
-Change in digital pulsatile pressure-Endothelium-independent vasodilation-Change in brachial artery blood flow velocity -Serum levels of inflammatory markers -Serum and urine levels of cytochrome P450 epoxygenase pathway biomarkers
Conditions Studied
Study Locations (1)
North Carolina
- NIEHS Clinical Research Unit (CRU) - Research Triangle Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 178 participants |
| Start Date | 2012-03-01 |
What the finished NCT01524549 record still lists
NCT01524549 is an observational study that tracks outcomes without assigning an intervention. The registered 178 participants enrollment target is mid-sized for trials with a published cap, below the 2,696-participant average among 137 other Cardiovascular Disease trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Cardiovascular Disease appearing as the primary indexed condition, and to 0 interventions.
NCT01524549 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT01524549 about?
NCT01524549 is a clinical study titled "Blood Vessel Study". Background: \- The endothelium is the inner lining of blood vessels. The cells in this lining help regulate blood flow and immune system function. Problems with endothelial cells can contribute to heart disease, high blood pressure, and diabetes. Certain genes or parts of genes may be related to pr...
What is the current status of trial NCT01524549?
This trial is currently completed. The enrollment target is 178 participants. The study started on 2012-03-01.
What conditions does trial NCT01524549 study?
This clinical trial studies the following conditions: Cardiovascular Disease.
Who is sponsoring clinical trial NCT01524549?
This trial is sponsored by National Institute of Environmental Health Sciences (NIEHS), which has 145 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01524549 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01524549's enrollment target sits among peer trials
178 54th of 137 higher than 84 of 137 other Cardiovascular Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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