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NCT06280807 · ClinicalTrials.gov registry record
Observation of Environment and Reproductive-Endocrine Effects
A clinical trial of Hypogonadism and Amenorrhea, sponsored by National Institute of Environmental Health Sciences (NIEHS).
- Recruiting
- Registry status
- 300
- Enrollment target
- 1
- Study location
NCT06280807: Recruiting study of Hypogonadism and Amenorrhea, sponsored by National Institute of Environmental Health Sciences (NIEHS).
NCT06280807 is a study of Hypogonadism and Amenorrhea that is actively recruiting participants, run by National Institute of Environmental Health Sciences (NIEHS). The registered enrollment target is 300 participants, above the 106-participant average among 21 other Hypogonadism trials with a reported enrollment target (183% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06280807, a study of Hypogonadism and Amenorrhea, is actively recruiting participants, sponsored by National Institute of Environmental Health Sciences (NIEHS).
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Endocrine disorders occur when the glands that make hormones do not work properly. Hormones levels that are too high or too low can cause problems such as late or early puberty, irregular periods, and infertility. Environmental factors - including pollution; chemical exposure at home and work; foods; medicines; and sleep habits - may cause problems with the endocrine and reproductive systems. Objective: To learn how environmental factors may affect the endocrine and reproductive systems. Eligibility: Males or females, referring to sex assigned at birth, aged 8 years and older; they must have hypogonadism, infertility, or other reproductive disorders. Design: Adult participants will have 4 to 5 visits in 5 years. Children may have up to 12 visits; they may remain in the study up to the age of 23. Most visits will be less than 3 hours. Participants will be screened. They will have a physical exam. They will have blood and urine tests. They will complete questionnaires; they will answer questions about their diet, health, and other topics. Some may be referred for additional tests, such as imaging scans and semen analysis. Specific tests conducted during study visits will vary, depending on the participant s diagnosis. In addition to repeated blood and urine tests, these may include: Body composition measure: Participants will sit in a pod-shaped machine for about 6 minutes. The machines measures the air inside the capsule to record body fat and breathing volume. Resting energy expenditure test: Participants will lie down with a clear dome placed over their head. They will breathe quietly for 30 minutes. This test measures the number of calories their body burns at rest. ...
Primary Outcome
We will analyze the correlation between internal exposures, and the longitudinal evolution of endocrine disorders. For instance, changes in PSQI (sleep) and DSM-5 (mood) questionnaire scores, research analytes and hormone metrics with treatment.
Conditions Studied
Study Locations (1)
North Carolina
- NIEHS Clinical Research Unit (CRU) - Research Triangle Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2024-07-01 |
| Est. Completion | 2039-03-31 |
What NCT06280807 shows while recruiting
NCT06280807 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 106-participant average among 21 other Hypogonadism trials with a reported enrollment target (183% higher).
The record links to 5 conditions, with Hypogonadism appearing as the primary indexed condition, and to 0 interventions.
NCT06280807 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06280807 about?
NCT06280807 is a clinical study titled "Observation of Environment and Reproductive-Endocrine Effects". Background: Endocrine disorders occur when the glands that make hormones do not work properly. Hormones levels that are too high or too low can cause problems such as late or early puberty, irregular periods, and infertility. Environmental factors - including pollution; chemical exposure at home an...
What is the current status of trial NCT06280807?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2024-07-01. Estimated completion is 2039-03-31.
What conditions does trial NCT06280807 study?
This clinical trial studies the following conditions: Hypogonadism, Amenorrhea, Hypergonadism, Precocious Puberty, Late Puberty.
Who is sponsoring clinical trial NCT06280807?
This trial is sponsored by National Institute of Environmental Health Sciences (NIEHS), which has 145 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06280807 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypogonadism
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06280807's enrollment target sits among peer trials
300 3rd of 21 higher than 19 of 21 other Hypogonadism trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypogonadism trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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