Study of Exposure to Chemicals in Consumer Products

Study Summary

Background: \- In a lifetime, a person may encounter tens of thousands of chemicals used as ingredients in the products they buy. It s not easy to measure them because the companies that sell the products don t have to tell the exact chemical ingredients. Researchers want to compare how existing methods (e.g., surveys and models) measure exposure to chemicals in personal care and household products. Objective: \- To test and improve the ways that studies gather data about contact with chemicals found in consumer products. Eligibility: \- Healthy women volunteers ages 35 74 who use at least 15 consumer products a day. Design: * Participants will be screened with medical history, pregnancy test, smoking test, and blood sample. They will answer questions about their homes and products they use. * Participation will last about 30 hours over 12 days. * Researchers will: * Place air samplers inside and outside participants homes for 10 days. One sampler will need to be plugged into an electrical outlet. It will make a low, continuous sound while in operation. * Collect house dust samples and record all consumer products in the house. * Visit the house daily to collect samples. * Participants will: * Give a blood sample at a clinic twice. * Collect all urine voids for 10 days. They will label it and put it in a special cooler. * Wear 4 small devices that measure air pollution, chemicals, location, and activity. * Record what they eat and what consumer products they use. They will write these in a diary and \<TAB\>photograph them on an iPhone provided to them. * On day 2 of the study, they will collect a duplicate sample of what they eat. * Take iPhone videos of their use of certain products. * Answer questions about chemical ingredients in their personal care products.