National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 16 of 41

COMPLETED

Interferon Responses in Eczema Herpeticum

NCT01429311

COMPLETED

Proteogenomic Biomarker Panels in a Serial Blood & Urine Monitoring Study of Kidney Transplant Recipients

NCT01289717

COMPLETED Phase 1

Safety of and Immune Response to an Investigational HIV-1 Vaccine With or Without Interleukin-12 (IL-12) in HIV-1 Infected Adults

NCT01266616

COMPLETED Phase 4

Safety and Immunogenicity of Sequential Rotavirus Vaccine Schedules

NCT01266850

COMPLETED Phase 1

Tenofovir Gel in Pregnancy and Lactation

NCT01136759

TERMINATED Phase 2

Inducing Remission in Type 1 Diabetes With Alefacept

NCT00965458

COMPLETED Phase 1

Phase I STEBVax in Healthy Adults

NCT00974935

COMPLETED Phase 1

Evaluation of the Safety and Immunogenicity of a Live Attenuated Human Metapneumovirus Vaccine

NCT01255410

COMPLETED

The Role of Epigenetics in Inner City Asthma

NCT01382836

COMPLETED Phase 1

Antigenic Competition in HIV Preventive Vaccines

NCT01159990

COMPLETED Phase 2

Safety and Efficacy of Investigational Anti-Influenza Immune Plasma in Treating Influenza

NCT01052480

COMPLETED

Evaluation of Influenza-Specific Immune Responses in Children and Adults During the 2010-2011 Influenza Season in the U.S.

NCT01262079

COMPLETED Phase 1

Evaluating the Safety and Immunogenicity of a Human Parainfluenza Type 3 (HPIV3) Virus Vaccine in Infants and Children

NCT01254175

COMPLETED Early Phase 1

Searching for Persistence of Infection in Lyme Disease

NCT01143558

COMPLETED

Screening Protocol for Genetic Diseases of Allergic Inflammation

NCT00852943

COMPLETED Phase 2

A Phase II/III Trial of Lopinavir/Ritonavir Dosed According to the WHO Pediatric Weight Band Dosing Guidelines

NCT01172535

COMPLETED Phase 1

Influenza Antiviral DAS181-F03

NCT01173224

COMPLETED Phase 1

Phase IC Study of Safety and PK of SQ109 300mg Daily

NCT01358162

TERMINATED Phase 2

Immune Monitoring and CNI Withdrawal in Low Risk Recipients of Kidney Transplantation

NCT01517984

COMPLETED Phase 1

Comparison of Flu Vaccine Doses in Children

NCT01164553

COMPLETED Phase 1

Cellular and Humoral Immune Response to Primary and Secondary Immunization With Subvirion H5N1 Vaccines

NCT01086566

TERMINATED Phase 1

A Research Trial of Aralast in New Onset Diabetes (RETAIN)

NCT01183468

COMPLETED Phase 1

Phase I Study of ETEC Vaccine

NCT01147445

TERMINATED

Multiplex Microarray Chip-Based Diagnosis of Respiratory Infections

NCT01212042

COMPLETED Phase 1

Evaluating Heterologous-Insert Prime-Boost HIV Vaccine Regimens in HIV-Uninfected Adults

NCT01095224

COMPLETED Phase 2

2010-2011 Trivalent Influenza Vaccine (TIV) in Pregnant Women

NCT01173211

COMPLETED Phase 1

Evaluating the Safety of ITX 5061 in Treatment-Naive Hepatitis C (HCV)-Infected Adults

NCT01165359

COMPLETED Phase 2

Comparing the Efficacy, Safety, and Tolerability of Combination Antivirals (Amantadine, Ribavirin, Oseltamivir) Versus Oseltamivir for the Treatment of Influenza in Adults at Risk for Complications

NCT01227967

COMPLETED Phase 2

Phase II Tularemia Vaccine Comparison

NCT01150695

COMPLETED Phase 1

Development of Cockroach Immunotherapy by the Inner-City Asthma Consortium

NCT01221285

COMPLETED

Associating Renal Transplantation With the ITN Signature of Tolerance

NCT01516177

COMPLETED Phase 1

Evaluation of the Safety and Immunogenicity of a Live Attenuated Virus Vaccine for the Prevention of H2N3 Influenza

NCT01175122

COMPLETED Phase 2

A Cooperative Clinical Study of Abatacept in Multiple Sclerosis

NCT01116427

COMPLETED Phase 1

ZOSTAVAX® in Renal Transplant Patients

NCT01137669

TERMINATED

Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders

NCT01212016

COMPLETED Phase 1

EP1300 Polyepitope DNA Vaccine Against Plasmodium Falciparum Malaria

NCT01169077

COMPLETED

Live Lung Donor Cross-sectional Cohort Study

NCT01524835

COMPLETED

Natural History of Severe Allergic Inflammation and Reactions

NCT01164241

TERMINATED

Collection of Blood, Bone Marrow, Leukapheresis, and Tissue Biopsy Samples From Patients and Their Family Members for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases Laboratory Research Studies

NCT01200823

COMPLETED Phase 1

Safety and Immunogenicity of Live Influenza A Vaccine for Avian Influenza H7N7

NCT00922259

COMPLETED Phase 1

Evaluating the Safety and Immune Response of an Adenovirus-Based HIV Vaccine in HIV-Uninfected Adults

NCT01103687

COMPLETED Phase 1

Evaluation of the Safety and Immune Response of Five Admixtures of a Tetravalent Dengue Virus Vaccine

NCT01072786

COMPLETED Phase 1

Group Study of the Safety of and Immune Response to a Single Dose of Bird Flu Vaccine (H7N3) in Healthy Adults

NCT00853255

TERMINATED

Open Label Study to Evaluate Chronic Hepatitis C Treatment in Latino Subjects With and Without HIV Co-infection

NCT01182298

COMPLETED

Immunogenicity of Off-Schedule Dosing of HPV Vaccine

NCT01030562

COMPLETED Phase 1

Safety of a Live Attenuated Human Parainfluenza Virus Type 2 (HPIV2) Vaccine for Adults, Children, and Infants

NCT01139437

COMPLETED Phase 4

Efficacy of Combination Therapies for Gonorrhea Treatment

NCT00926796

COMPLETED Phase 1

Booster Trial to 07-0019 With A/Anhui/05 With and Without MF59

NCT00912496

COMPLETED Phase 1

Safety Study of a Human Metapneumovirus Challenge Virus in Healthy Adults

NCT01109329

TERMINATED Phase 4

Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease

NCT01147042

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.