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NCT00922259 · ClinicalTrials.gov registry record · Phase 1

Safety and Immunogenicity of Live Influenza A Vaccine for Avian Influenza H7N7

A Phase 1 study of Influenza a, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
25
Enrollment target
1
Study location

NCT00922259 is a Phase 1 study of Influenza a that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 25 participants, below the 2,752-participant average among 10 other Influenza a trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00922259, a Phase 1 study of Influenza a, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
25 participants
Enrollment target
1
Study location

Study Summary

Every year the human population suffers from seasonal outbreaks of influenza resulting in both illness and death. However, the rates of illness and death from seasonal outbreaks are significantly lower than those suffered during times of influenza pandemic, such as those experienced in 1918, 1957, and 1968. The reason for this difference lies in presence of immunity within a population. With seasonal outbreaks of influenza most people have some immunity to the circulating strain and usually only those with weakened immune systems experience serious complications. Influenza pandemics, in contrast, are the result of a completely new viral subtype to which nobody possesses an immunity, leaving everyone vulnerable to the most serious of complications. It has been estimated that the next flu pandemic could cause over 200,000 deaths and over 700,000 hospitalizations in the US alone. The need for an effective viral vaccine is high. The purpose of this study is to test the safety and immunogenicity of a live influenza A strain vaccine, which would be able to combat an influenza pandemic.

Conditions Studied

Interventions

  • BIOLOGICAL Influenza A H7N7 vaccine

Study Locations (1)

New York

  • University of Rochester Medical Center - Rochester

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2010-07
Est. Completion 2012-01
Phase Phase 1

What the Registry Record Tells You About NCT00922259

The ClinicalTrials.gov registry entry for NCT00922259 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,752-participant average among 10 other Influenza a trials with a reported enrollment target (99% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Influenza a appearing as the primary indexed condition, and to 1 intervention - of which Influenza A H7N7 vaccine is the first listed.

NCT00922259 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT00922259 about?

NCT00922259 is a clinical study titled "Safety and Immunogenicity of Live Influenza A Vaccine for Avian Influenza H7N7". Every year the human population suffers from seasonal outbreaks of influenza resulting in both illness and death. However, the rates of illness and death from seasonal outbreaks are significantly lower than those suffered during times of influenza pandemic, such as those experienced in 1918, 1957, a...

What is the current status of trial NCT00922259?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2010-07. Estimated completion is 2012-01.

What conditions does trial NCT00922259 study?

This clinical trial studies the following conditions: Influenza a.

What interventions are being tested in trial NCT00922259?

The interventions under investigation include: Influenza A H7N7 vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT00922259?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00922259 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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