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NCT01072786 · ClinicalTrials.gov registry record · Phase 1

Evaluation of the Safety and Immune Response of Five Admixtures of a Tetravalent Dengue Virus Vaccine

A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
141
Enrollment target

NCT01072786: Completed Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT01072786 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 141 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (135% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01072786, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
141 participants
Enrollment target

Study Summary

Dengue viruses can cause dengue fever and other serious health conditions, primarily affecting people living in tropical regions of the world. This study will evaluate the safety and immune responses of five formulations of a tetravalent dengue virus vaccine in healthy adults.

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL TetraVax-DV Vaccine-Admixture 1
  • BIOLOGICAL TetraVax-DV Vaccine-Admixture 2
  • BIOLOGICAL TetraVax-DV Vaccine-Admixture 3
  • BIOLOGICAL TetraVax-DV Vaccine-Admixture 4

Trial Details

FieldValue
Enrollment Target 141 participants
Start Date 2010-07
Est. Completion 2012-06
Phase Phase 1

What the finished NCT01072786 record still lists

NCT01072786 is an interventional study that assigns participants to a tested intervention. The registered 141 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (135% higher).

The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.

NCT01072786 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01072786 about?

NCT01072786 is a clinical study titled "Evaluation of the Safety and Immune Response of Five Admixtures of a Tetravalent Dengue Virus Vaccine". Dengue viruses can cause dengue fever and other serious health conditions, primarily affecting people living in tropical regions of the world. This study will evaluate the safety and immune responses of five formulations of a tetravalent dengue virus vaccine in healthy adults.

What is the current status of trial NCT01072786?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 141 participants. The study started on 2010-07. Estimated completion is 2012-06.

What interventions are being tested in trial NCT01072786?

The interventions under investigation include: Placebo (BIOLOGICAL), TetraVax-DV Vaccine-Admixture 1 (BIOLOGICAL), TetraVax-DV Vaccine-Admixture 2 (BIOLOGICAL), TetraVax-DV Vaccine-Admixture 3 (BIOLOGICAL), TetraVax-DV Vaccine-Admixture 4 (BIOLOGICAL).

Who is sponsoring clinical trial NCT01072786?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01072786's enrollment target sits among peer trials

141 401st of 2000 higher than 1,599 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01072786, the US trial registry maintained by the National Library of Medicine. NCT01072786 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.