National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 15 of 41

COMPLETED Phase 1

Staged Phase I/II Hepatitis C Prophylactic Vaccine

NCT01436357

COMPLETED Phase 3

Quadrivalent HPV Vaccine to Prevent Anal HPV in HIV-infected Men and Women

NCT01461096

COMPLETED Phase 1

Evaluating the Safety and Immune Response of an H7N7 Vaccine in Healthy Adults

NCT01534468

COMPLETED Phase 4

Steroid Treatment for Hypereosinophilic Syndrome

NCT01524536

COMPLETED Phase 1

Influenza A 2009 H1N1 Challenge Study in Healthy Adults

NCT01646138

COMPLETED Phase 1

Dose Escalation Trial of a Plague Vaccine, Flagellin/F1/V, in Healthy Adult Volunteers

NCT01381744

COMPLETED

HIV Accelerated Liver Disease in Uganda

NCT01524562

COMPLETED Phase 1

Evaluating the Safety and Immune Response to Two Admixtures of a Tetravalent Dengue Virus Vaccine

NCT01506570

COMPLETED Phase 1

Seasonal Influenza DNA Vaccine Prime With Trivalent Inactivated Vaccine (TIV) Boost Compared to TIV Alone

NCT01498718

COMPLETED Phase 1

Evaluating the Immune Response to a rAd5 HIV Vaccine Administered in Three Different Ways in Healthy, HIV-Uninfected Adults

NCT01479296

COMPLETED Phase 1

Chikungunya Virus Vaccine Trial in Healthy Adults

NCT01489358

TERMINATED Early Phase 1

A Study to Determine the Immunogenicity and Oral Tolerance to Keyhole Limpet Hemocyanin (KLH)

NCT01489956

COMPLETED Early Phase 1

Atopic Dermatitis Research Network (ADRN) Influenza Vaccine Pilot

NCT01518478

TERMINATED Phase 1

Detoxified J5 Core Glycolipid/ Group B Meningococcal Outer Membrane Protein Vaccine for Gram-negative Bacterial Sepsis Administered With and Without Synthetic CPG Oligodeoxynucleotide 7909 Adjuvant

NCT01164514

COMPLETED Phase 1

TMC207 +/- Rifabutin/Rifampin

NCT01341184

COMPLETED Phase 1

Evaluating the Safety of and Immune Response to the VSV-Indiana HIV Vaccine in Healthy, HIV-Uninfected Adults

NCT01438606

COMPLETED Phase 1

Evaluating the Safety and Immune Response to an H5N1 Influenza Vaccine in People Who Have Previously Received an H5N1 or H7N3 Influenza Vaccine and in People Who Have Never Received a Live Attenuated Influenza Vaccine

NCT01443663

COMPLETED Phase 2

TIV and High Dose TIV in Subjects With Rheumatoid Arthritis

NCT01436370

COMPLETED

Assessment of Alterations in Immune Function During Pregnancy and Post Parturition

NCT01200979

COMPLETED Phase 1

Experimental PfSPZ Vaccine in Adults Without Malaria

NCT01441167

COMPLETED Phase 1

Experimental AD4-H5-VTN Vaccine in Healthy Volunteers

NCT01443936

COMPLETED Phase 1

GS-7977 With Ribavirin for Hepatitis C (SPARE)

NCT01441180

COMPLETED Phase 2

Post-Partum Immunization With Live Attenuated Influenza Vaccine (LAIV) or Trivalent Influenza Vaccine (TIV) in Post-Partum Breast Feeding Women

NCT01181323

COMPLETED Phase 4

Preventative Omalizumab or Step-up Therapy for Severe Fall Exacerbations

NCT01430403

TERMINATED Phase 2

Optimization of NULOJIX® Usage As A Means of Avoiding CNI and Steroids in Renal Transplantation

NCT01436305

TERMINATED Phase 4

Boceprevir Drug Combination for Hepatitis C Treatment in People With and Without HIV

NCT01443923

TERMINATED Phase 2

Prevention of Cardiac Allograft Vasculopathy Using Rituximab (Rituxan) Therapy in Cardiac Transplantation

NCT01278745

COMPLETED Phase 1

Influenza Antiviral DAS-181-F04 in Healthy Adults

NCT01651494

COMPLETED Phase 1

Initial Study of Malaria Vaccine Pfs25-EPA/Alhydrogel(Registered Trademark)

NCT01434381

COMPLETED

Registry for the Atopic Dermatitis Research Network

NCT01494142

COMPLETED

Asthma Phenotypes in the Inner City

NCT01383941

COMPLETED Phase 1

Evaluating the Safety and Immune Response to a Respiratory Syncytial Virus (RSV) Vaccine in Adults, RSV-Seropositive Children, and RSV-Seronegative Infants and Children

NCT01459198

COMPLETED Phase 1

Evaluating the Safety and Immune Response to an HIV Vaccine Boost Following the Administration of Two HIV Vaccines, in HIV-Uninfected, Healthy Adults (Study Extension to HVTN 073/SAAVI 102)

NCT01423825

COMPLETED Phase 1

Evaluating the Safety and Immune Response to Two Admixtures of a Tetravalent Dengue Virus Vaccine

NCT01436422

TERMINATED Early Phase 1

Research Study of ATG and Rituximab in Renal Transplantation

NCT01318915

COMPLETED Phase 1

Evaluating the Safety and Immune Response to an HIV Vaccine in Healthy, HIV-Uninfected Adults Who Have Participated in Previous HIV Vaccine Clinical Trials and in Adults Who Have Not Participated in Previous HIV Vaccine Clinical Trials

NCT01376726

COMPLETED Phase 2

Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)

NCT01086540

COMPLETED Phase 1

Immune Responses to Two Experimental HIV Vaccines in Healthy Adults

NCT01386489

TERMINATED

Utility of MODS for Diagnosis of MDR-TB and Second-Line Antituberculous Drug Susceptibility Testing in Mali

NCT01381757

COMPLETED

Evaluating the Safety and Pharmacokinetics of Raltegravir in Infants

NCT01828073

COMPLETED

Extended Follow-Up After Islet Transplantation in T1D

NCT01369082

COMPLETED Phase 1

H5N1 Mix and Match With MF59

NCT01317745

COMPLETED Phase 1

Phase 1 PK Study of XOMA 3AB

NCT01357213

COMPLETED Phase 1

Biomarkers of Cockroach Sublingual Immunotherapy 2

NCT01380327

COMPLETED Phase 1

Immune Response to an HIV DNA Plasmid Vaccine Prime Followed by Adenovirus Boost in HIV-uninfected Individuals

NCT00955006

COMPLETED Phase 1

H5N1 Mix and Match With AS03

NCT01317758

COMPLETED Phase 1

Safety of and Immune Response to Dolutegravir in HIV-1 Infected Infants, Children, and Adolescents

NCT01302847

COMPLETED Phase 2

Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative Women

NCT01230814

COMPLETED

Eosinophilic Esophagitis Databank

NCT01323803

COMPLETED NA

Evaluating the Use of Oseltamivir for the Treatment of Influenza in Adults

NCT01314911

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.