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NCT01164553 · ClinicalTrials.gov registry record · Phase 1

Comparison of Flu Vaccine Doses in Children

A Phase 1 study of Influenza, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
243
Enrollment target
7
Study locations

NCT01164553 is a Phase 1 study of Influenza that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 243 participants, below the 36,802-participant average among 156 other Influenza trials with a reported enrollment target (99% lower). The trial reports 7 study locations across 6 states.

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The verdict

NCT01164553, a Phase 1 study of Influenza, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
243 participants
Enrollment target
7
Study locations

Study Summary

The purpose of this study is to evaluate the possibility that giving an increased dose of flu vaccine to children 6 through 35 months of age will improve protection against influenza without increasing side effects. Investigators will evaluate the body's response to the vaccine. Male and female participants' ages 6-35 months, who have never received flu vaccine, and those ages 12-35 months, who have been previously vaccinated, will participate in the study for about 7 months. Vaccine naïve study participants will receive two doses of flu vaccine, either the 0.25 mL dose (Group 1) or 0.5 mL dose (Group 2). Previously vaccinated subjects will receive one dose of flu vaccine, either the 0.25 mL dose (Group 1) or 0.5 mL dose (Group 2). Study procedures include physical examination, memory aids, blood sampling and a follow-up phone call about 6 months after the last vaccine dose.

Conditions Studied

Interventions

  • BIOLOGICAL Trivalent Inactivated Influenza Vaccine

Study Locations (7)

Georgia

  • Emory Children's Center - Pediatric Infectious Diseases - Atlanta
  • Emory University School of Medicine - Emory Children's Center - Pediatric Infectious Diseases - Atlanta

Iowa

  • University of Iowa - Infectious Disease Clinic - Iowa City

Maryland

  • University of Maryland School of Medicine - Center for Vaccine Development - Baltimore - Baltimore

Missouri

  • Saint Louis University - Center for Vaccine Development - St Louis

Ohio

  • Cincinnati Children's Hospital Medical Center - Infectious Diseases - Cincinnati

Tennessee

  • Vanderbilt University - Pediatric - Infectious Diseases - Nashville

Trial Details

FieldValue
Enrollment Target 243 participants
Start Date 2010-10
Est. Completion 2012-10
Phase Phase 1

What the Registry Record Tells You About NCT01164553

The ClinicalTrials.gov registry entry for NCT01164553 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 243 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 36,802-participant average among 156 other Influenza trials with a reported enrollment target (99% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Influenza appearing as the primary indexed condition, and to 1 intervention - of which Trivalent Inactivated Influenza Vaccine is the first listed.

NCT01164553 reports 7 study locations spanning 6 distinct geographic areas - top geographies include Georgia, Iowa, Maryland.

Frequently Asked Questions

What is clinical trial NCT01164553 about?

NCT01164553 is a clinical study titled "Comparison of Flu Vaccine Doses in Children". The purpose of this study is to evaluate the possibility that giving an increased dose of flu vaccine to children 6 through 35 months of age will improve protection against influenza without increasing side effects. Investigators will evaluate the body's response to the vaccine. Male and female part...

What is the current status of trial NCT01164553?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 243 participants. The study started on 2010-10. Estimated completion is 2012-10.

What conditions does trial NCT01164553 study?

This clinical trial studies the following conditions: Influenza.

What interventions are being tested in trial NCT01164553?

The interventions under investigation include: Trivalent Inactivated Influenza Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT01164553?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01164553 being conducted?

This trial has 7 study locations across Georgia, Iowa, Maryland, Missouri, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.