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NCT01095224 · ClinicalTrials.gov registry record · Phase 1

Evaluating Heterologous-Insert Prime-Boost HIV Vaccine Regimens in HIV-Uninfected Adults

A Phase 1 study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
180
Enrollment target
8
Study locations

NCT01095224 is a Phase 1 study of HIV Infections that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 180 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (60% lower). The trial reports 8 study locations across 6 states.

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The verdict

NCT01095224, a Phase 1 study of HIV Infections, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
180 participants
Enrollment target
8
Study locations

Study Summary

The purpose of this study is to evaluate the safety and immune response of an adenovirus-based HIV-1 vaccine regimen that includes two vaccines given at different time points in HIV-uninfected adults.

Conditions Studied

Interventions

  • BIOLOGICAL rAd35 Env A
  • BIOLOGICAL rAd5 Env A
  • BIOLOGICAL rAd5 Env B

Study Locations (8)

New York

  • Columbia P&S CRS - New York
  • New York Blood Center CRS - New York
  • University of Rochester Vaccines to Prevent HIV Infection CRS - Rochester

Alabama

  • Alabama CRS - Birmingham

California

  • Bridge HIV CRS - San Francisco

Georgia

  • The Hope Clinic of the Emory Vaccine Center CRS - Decatur

Massachusetts

  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS) - Boston

Tennessee

  • Vanderbilt Vaccine (VV) CRS - Nashville

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2010-09
Est. Completion 2016-02
Phase Phase 1

What the Registry Record Tells You About NCT01095224

The ClinicalTrials.gov registry entry for NCT01095224 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (60% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 3 interventions - of which rAd35 Env A is the first listed.

NCT01095224 reports 8 study locations spanning 6 distinct geographic areas - top geographies include New York, Alabama, California.

Frequently Asked Questions

What is clinical trial NCT01095224 about?

NCT01095224 is a clinical study titled "Evaluating Heterologous-Insert Prime-Boost HIV Vaccine Regimens in HIV-Uninfected Adults". The purpose of this study is to evaluate the safety and immune response of an adenovirus-based HIV-1 vaccine regimen that includes two vaccines given at different time points in HIV-uninfected adults.

What is the current status of trial NCT01095224?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 180 participants. The study started on 2010-09. Estimated completion is 2016-02.

What conditions does trial NCT01095224 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT01095224?

The interventions under investigation include: rAd35 Env A (BIOLOGICAL), rAd5 Env A (BIOLOGICAL), rAd5 Env B (BIOLOGICAL).

Who is sponsoring clinical trial NCT01095224?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01095224 being conducted?

This trial has 8 study locations across Alabama, California, Georgia, Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.