National Human Genome Research Institute (NHGRI)
National Human Genome Research Institute (NHGRI) sponsors 185 registered US clinical trials on ClinicalTrials.gov, 30 of them currently recruiting, and 143 completed. 0 of these trials are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Proteus Syndrome, with 3 trials.
Trial Pipeline
185 total, page 2 of 4
An Open Label Phase 2 Study of ManNAc in Subjects With GNE Myopathy
NCT02346461
Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry Protocol
NCT02322177
Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease
NCT02281760
Physicians' Experiences With and Attitudes Toward Non-Medical Sex Selection Through Preimplantation Genetic Diagnosis
NCT02225171
Where Does Hope Fit In? The Relationship Between Hope, Uncertainty, and Coping Efficacy in Mothers of Children With Duchenne/Becker Muscular Dystrophy
NCT02194725
Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS Study)
NCT02156102
Study on Moebius Syndrome and Congenital Facial Weakness Disorders
NCT02055248
A Study of Consent Forms for Whole Exome and Whole Genome Sequencing
NCT01927770
Treatment of SCID Due to ADA Deficiency With Autologous Transplantation of Cord Blood or Hematopoietic CD 34+ Cells After Addition of a Normal Human ADA cDNA by the EFS-ADA Lentiviral Vector
NCT02022696
Black Family Eating Behaviors Study
NCT02015078
Participation in a Research Registry for Immune Disorders
NCT01953016
The Genetic Basis of Congenital Heart Disease in Africa
NCT01952171
Patient Perspectives and Doctor Visits
NCT01888913
The Role of Uncertainty in Coping: The Experience of Parents of Children With Undiagnosed Medical Conditions
NCT01905865
Adaptation to Living With a BRCA1/2 Mutation
NCT01866865
Genetic Studies of Non-Alcoholic Fatty Liver Disease
NCT01629095
Effect of Lung Cancer Diagnoses on Family Behaviors
NCT01862770
Genetic, Brain Structure, and Environmental Effects on ADHD
NCT01721720
Phase I Clinical Trial of ManNAc in Patients With GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM)
NCT01634750
EPI-743 for Metabolism or Mitochondrial Disorders
NCT01642056
The Clinical Study of Sex Chromosome Variants
NCT01661010
Developing the Family Map: Looking at Communal Coping
NCT01633021
Living With Frontotemporal Dementia
NCT01738386
Testing Spanish-language Genetic Literacy
NCT01610583
Uncertain Genetic Test Results for Lynch Syndrome
NCT01646112
Weight Management Interactions in a Virtual Clinical Environment
NCT01443910
Inherited Diseases, Caregiving, and Social Networks
NCT01498263
Family Genetics Health Education and Healthy Behaviors
NCT01498276
The NIH UNI Study: Urea Cycle Disorders, Nutrition and Immunity
NCT01421888
Clinical and Pathophysiological Investigations Into Erdheim Chester Disease
NCT01417520
Family Communication of Hereditary Breast and Ovarian Cancer Risk Among African Americans
NCT01374685
The Role of Family Functioning in Promoting Adaptation in Siblings of Individuals With Duchenne Muscular Dystrophy (DMD)
NCT01386515
Informed Consent for Whole Genome Sequencing: Ideals and Norms Referenced by Early Participants
NCT01369953
Personalized Genomic Research
NCT01294345
Mothers' Thoughts About Kids and Eating
NCT01087346
The PTC124 (Ataluren) Clinical Trial for Duchenne Muscular Dystrophy: Exploration of the Experiences of Parents, Clinician Researchers, and the Industry Sponsor
NCT01182324
The Role of Social Comparisons in Coping and Quality of Life Following a Prostate Cancer Diagnosis
NCT01176526
A Coping Effectiveness Training Intervention for Caregivers of Children With Autism Spectrum: A Feasibility Study
NCT01168284
The Perceived Impact of Children s Risk Status for Hypertrophic Cardiomyopathy on Families: an Exploratory Study
NCT01160536
Parents With Bipolar Disorder: Relationship of Adaptation to Own Illness With Risk Perception and Coping With Perceived Risk to a Child
NCT01012180
The Experience of Uncertainty in Parents of Children With an Undiagnosed Medical Condition
NCT00955370
Reactions to Disease Risk Information
NCT00774254
The Roles of Trust and Respect in Patient Reactions to Race-based and Personalized Medicine Vignettes: An Experimental Study
NCT00911833
Adaptation Among Adolescents and Adults With Klinefelter Syndrome
NCT00896272
The Role of Family Functioning in Adaptation to Being a Caregiver of an Individual With Rett Syndrome
NCT00891956
The Nosology and Etiology of Leukodystrophies of Unknown Causes
NCT00889174
Clinical, Cellular, and Molecular Investigation Into Oculocutaneous Albinism
NCT00808106
Clinical and Genetic Studies of VACTERL Association
NCT00766571
Cultural Congruence in International Genetics Research
NCT00767858
Use of Population Descriptors in Human Genetic Research
NCT00767702
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 11 |
| Phase 2 | 7 |
Therapeutic Areas
What the Pipeline for National Human Genome Research Institute (NHGRI) Shows
According to the ClinicalTrials.gov registry, National Human Genome Research Institute (NHGRI) is linked to 185 US clinical trials across every stage of research activity. Of those, 30 studies are currently recruiting, about 16% of the sponsor's indexed portfolio, and 143 are already marked complete, representing roughly 77% of the total.
The phase mix for National Human Genome Research Institute (NHGRI) reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 18 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Human Genome Research Institute (NHGRI) is Proteus Syndrome with 3 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.