National Human Genome Research Institute (NHGRI)

185 total trials 30 currently recruiting 143 completed

National Human Genome Research Institute (NHGRI) sponsors 185 registered US clinical trials on ClinicalTrials.gov, 30 of them currently recruiting, and 143 completed. 0 of these trials are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Proteus Syndrome, with 3 trials.

Trial Pipeline

185 total, page 3 of 4

COMPLETED

A Study of the Genetic Analysis of Brain Disorders

NCT00645645

COMPLETED

Screening Behavior in Adults With Hereditary Hemorrhagic Telangiectasia

NCT00684879

COMPLETED

Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I

NCT00684398

COMPLETED

The Experience of Caregivers of Children With Down Syndrome

NCT00695695

COMPLETED NA

Patient Provider Communication and Interaction in a Virtual Clinical Setting

NCT00669188

COMPLETED

Making Sense of a Positive Genetic Test Result for Huntington Disease

NCT00539747

COMPLETED

Informed Choice Regarding Invasive Prenatal Testing

NCT00514553

COMPLETED Phase 1

Treatment Strategies for Children With Smith-Magenis Syndrome

NCT00506259

COMPLETED

Predictors of Caregiver Adaptation to Pervasive Developmental Disorders

NCT00496210

COMPLETED

Individuals Patterns of Disclosure About Huntington s Disease (HD) and the Association With Adaptation to HD

NCT00491842

COMPLETED

African American Families and Lung Cancer Study

NCT00487760

COMPLETED

Disclosing a Cystic Fibrosis Diagnosis to a Dating Partner

NCT00485082

COMPLETED

Risk Communication Within Mexican-American Families

NCT00469339

TERMINATED Phase 1

Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak Syndrome

NCT00467831

COMPLETED NA

Interventions to Educate An Underserved Population About Inherited Disease Risks

NCT00441077

COMPLETED

Genetic Counselors' Experiences of Moral Value Conflicts With Clients

NCT00360711

COMPLETED

Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations

NCT00302146

COMPLETED

Patients' Perspectives on Identity, Ancestry and Genetics

NCT00359710

COMPLETED

Use of Virtual Reality to Communicate Concepts of Genomics to the General Public

NCT00316056

COMPLETED

Invasive Prenatal Testing Decisions in Pregnancy After Infertility

NCT00341822

COMPLETED

Experiences of Genetics Patients With Visible Abnormalities Who Facilitate Teaching in Genetics Clinics

NCT00341718

COMPLETED

Perspectives of Individuals With Bipolar Disorder and Siblings of Individuals With Bipolar Disorder; A Telephone Interview Study

NCT00300820

COMPLETED

Psychosocial Aspects of Genetic Testing for Hereditary Nonpolyposis Colon Cancer

NCT00341575

COMPLETED Phase 1

Intravenous Immune Globulin to Treat Hereditary Inclusion Body Myopathy

NCT00195637

COMPLETED

Physicians' Understanding of Human Genetic Variation

NCT00339924

COMPLETED

Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial Differences

NCT00340964

COMPLETED

Developing Newborn Screening for Infants With Primary Immunodeficiency

NCT00113464

COMPLETED

Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)

NCT00106977

COMPLETED

Analysis of Data From the Women's Contraceptive and Reproductive Experiences (CARE) Study

NCT00341159

COMPLETED

Genetic Analysis of Craniofrontonasal Syndrome

NCT00339846

COMPLETED

Genetic Analysis of Craniosynostosis, Philadelphia Type

NCT00367796

COMPLETED Phase 2

Long-Term Study of Nitisinone to Treat Alkaptonuria

NCT00107783

COMPLETED

Prevalence of Ambivalence Regarding Prenatal Testing

NCT00342069

COMPLETED

Impact of Lung Cancer Diagnosis on Relatives' Understanding of Genetic Risk and Receptivity to Quit Smoking

NCT00341341

COMPLETED

Clinical Integration of Genetic Risk Assessment in Family Medicine

NCT00339794

COMPLETED

Identification of Prostate Cancer Genes

NCT00342784

COMPLETED

Clinical Studies of Progeria

NCT00094393

COMPLETED

Study of Megakaryocytes From Patients With Abnormal Platelet Vesicles

NCT00086476

TERMINATED

Genetics and Clinical Characteristics of Bardet-Biedl Syndrome

NCT00078091

COMPLETED

Genetic Studies in the Amish and Mennonites

NCT00359580

COMPLETED

Clinical and Genetic Studies on Holoprosencephaly

NCT00088426

COMPLETED

Cell Studies of Parkinson's Disease

NCT00076505

COMPLETED

Genetic Studies of Inflammatory Bowel Disease

NCT00340444

COMPLETED

Genetic Analysis of Gray Platelet Syndrome

NCT00069680

COMPLETED

Genetic Epidemiology of Lung Cancer

NCT00341835

COMPLETED

The Value of Genetic Information to Adult Adopted Individuals

NCT00057694

COMPLETED

Clinical and Molecular Investigations Into Ciliopathies

NCT00068224

COMPLETED

Transitional Life Events in Patients With Friedreich's Ataxia: Implications for Genetic Counseling

NCT00056186

COMPLETED

Family Studies of Eye Traits

NCT00342342

COMPLETED NA

Pilot Study of the Process of Prenatal Genetic Counseling

NCT00047905

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What the Pipeline for National Human Genome Research Institute (NHGRI) Shows

According to the ClinicalTrials.gov registry, National Human Genome Research Institute (NHGRI) is linked to 185 US clinical trials across every stage of research activity. Of those, 30 studies are currently recruiting, about 16% of the sponsor's indexed portfolio, and 143 are already marked complete, representing roughly 77% of the total.

The phase mix for National Human Genome Research Institute (NHGRI) reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 18 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Human Genome Research Institute (NHGRI) is Proteus Syndrome with 3 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.