National Human Genome Research Institute (NHGRI)
National Human Genome Research Institute (NHGRI) sponsors 185 registered US clinical trials on ClinicalTrials.gov, 30 of them currently recruiting, and 143 completed. 0 of these trials are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Proteus Syndrome, with 3 trials.
Trial Pipeline
185 total, page 3 of 4
A Study of the Genetic Analysis of Brain Disorders
NCT00645645
Screening Behavior in Adults With Hereditary Hemorrhagic Telangiectasia
NCT00684879
Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I
NCT00684398
The Experience of Caregivers of Children With Down Syndrome
NCT00695695
Patient Provider Communication and Interaction in a Virtual Clinical Setting
NCT00669188
Making Sense of a Positive Genetic Test Result for Huntington Disease
NCT00539747
Informed Choice Regarding Invasive Prenatal Testing
NCT00514553
Treatment Strategies for Children With Smith-Magenis Syndrome
NCT00506259
Predictors of Caregiver Adaptation to Pervasive Developmental Disorders
NCT00496210
Individuals Patterns of Disclosure About Huntington s Disease (HD) and the Association With Adaptation to HD
NCT00491842
African American Families and Lung Cancer Study
NCT00487760
Disclosing a Cystic Fibrosis Diagnosis to a Dating Partner
NCT00485082
Risk Communication Within Mexican-American Families
NCT00469339
Pilot Study of a Multi-Drug Regimen for Severe Pulmonary Fibrosis in Hermansky-Pudlak Syndrome
NCT00467831
Interventions to Educate An Underserved Population About Inherited Disease Risks
NCT00441077
Genetic Counselors' Experiences of Moral Value Conflicts With Clients
NCT00360711
Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations
NCT00302146
Patients' Perspectives on Identity, Ancestry and Genetics
NCT00359710
Use of Virtual Reality to Communicate Concepts of Genomics to the General Public
NCT00316056
Invasive Prenatal Testing Decisions in Pregnancy After Infertility
NCT00341822
Experiences of Genetics Patients With Visible Abnormalities Who Facilitate Teaching in Genetics Clinics
NCT00341718
Perspectives of Individuals With Bipolar Disorder and Siblings of Individuals With Bipolar Disorder; A Telephone Interview Study
NCT00300820
Psychosocial Aspects of Genetic Testing for Hereditary Nonpolyposis Colon Cancer
NCT00341575
Intravenous Immune Globulin to Treat Hereditary Inclusion Body Myopathy
NCT00195637
Physicians' Understanding of Human Genetic Variation
NCT00339924
Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial Differences
NCT00340964
Developing Newborn Screening for Infants With Primary Immunodeficiency
NCT00113464
Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)
NCT00106977
Analysis of Data From the Women's Contraceptive and Reproductive Experiences (CARE) Study
NCT00341159
Genetic Analysis of Craniofrontonasal Syndrome
NCT00339846
Genetic Analysis of Craniosynostosis, Philadelphia Type
NCT00367796
Long-Term Study of Nitisinone to Treat Alkaptonuria
NCT00107783
Prevalence of Ambivalence Regarding Prenatal Testing
NCT00342069
Impact of Lung Cancer Diagnosis on Relatives' Understanding of Genetic Risk and Receptivity to Quit Smoking
NCT00341341
Clinical Integration of Genetic Risk Assessment in Family Medicine
NCT00339794
Identification of Prostate Cancer Genes
NCT00342784
Clinical Studies of Progeria
NCT00094393
Study of Megakaryocytes From Patients With Abnormal Platelet Vesicles
NCT00086476
Genetics and Clinical Characteristics of Bardet-Biedl Syndrome
NCT00078091
Genetic Studies in the Amish and Mennonites
NCT00359580
Clinical and Genetic Studies on Holoprosencephaly
NCT00088426
Cell Studies of Parkinson's Disease
NCT00076505
Genetic Studies of Inflammatory Bowel Disease
NCT00340444
Genetic Analysis of Gray Platelet Syndrome
NCT00069680
Genetic Epidemiology of Lung Cancer
NCT00341835
The Value of Genetic Information to Adult Adopted Individuals
NCT00057694
Clinical and Molecular Investigations Into Ciliopathies
NCT00068224
Transitional Life Events in Patients With Friedreich's Ataxia: Implications for Genetic Counseling
NCT00056186
Family Studies of Eye Traits
NCT00342342
Pilot Study of the Process of Prenatal Genetic Counseling
NCT00047905
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 11 |
| Phase 2 | 7 |
Therapeutic Areas
What the Pipeline for National Human Genome Research Institute (NHGRI) Shows
According to the ClinicalTrials.gov registry, National Human Genome Research Institute (NHGRI) is linked to 185 US clinical trials across every stage of research activity. Of those, 30 studies are currently recruiting, about 16% of the sponsor's indexed portfolio, and 143 are already marked complete, representing roughly 77% of the total.
The phase mix for National Human Genome Research Institute (NHGRI) reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 18 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Human Genome Research Institute (NHGRI) is Proteus Syndrome with 3 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.