Mayo Clinic
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).
Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.
Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.
Top-decile sponsor footprint
Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,844 total, page 5 of 57
PACTAID App in Adults With Type 1 Diabetes to Help Manage Exercise
NCT06730906
Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial
NCT06764095
Probiotic in Patients With Bile Acid Malabsorption/Diarrhea
NCT06609148
Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)
NCT06752577
Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium
NCT06624592
Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodulator
NCT06684470
Postoperative Outcomes and Patient Satisfaction With Mayo Clinic Florida Care Hotel After Mastectomy and Tissue Expander Placement
NCT06783179
Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant
NCT06271616
Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts
NCT06271291
Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy
NCT06723041
Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer
NCT06381154
3D DL Ozteo in the Detection of Osseous Changes in Patients With Inflammatory Arthritis
NCT06383585
Outcomes of Low-Risk Endometrial Cancer With Isolated Tumor Cells in the Sentinel Lymph Nodes: A Prospective, Multicenter, Single-Arm Observational Study
NCT06689956
Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning
NCT06200116
Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice:
NCT06322238
Understanding the Mechanisms of Clonal and Non-clonal Cytopenia Following CAR-T Therapy for Multiple Myeloma or CD19+ Lymphoproliferative Disorder (LPD)
NCT06630104
Non-invasive Venous Air Plethysmography Assessment of Venous Hemodynamics in Patients Suspected Deep Venous Obstruction Used in Conjunction With Intermittent Pneumatic Compression.
NCT06519435
Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer
NCT06660407
Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial
NCT06639074
AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic Dysfunction
NCT06580158
A 3D-Printed External Breast Prosthesis for the Improvement of Patient-reported Outcomes Among Breast Cancer Patients That Underwent a Mastectomy Without Reconstruction
NCT07047872
Individualizing Corticosteroid Use in Pneumonia
NCT05334316
A Study of Sex Differences in Neurocirculatory Control
NCT06261034
Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery
NCT06450873
Growth Hormone for the Treatment of Gastroparesis
NCT06803589
Diaphragmatic Breathing for the Treatment of Bloating and Distension
NCT06596759
Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity Using the Vigilant App
NCT06675643
FDG-PET as an Imaging Modality to Diagnose and Risk Stratify Subclinical, Imaging Negative Ici-Myocarditis
NCT06566209
Inspiratory Muscle Training in HFpEF
NCT06510231
Contrast-Enhanced Photon-Counting Detector CT (PCD-CT) for the Local Staging of Rectal Cancer
NCT06965166
Genetic Testing for the Prevention of Cancer in Indigenous American Communities (JUNIPER Trial)
NCT06569316
Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog
NCT06614309
MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian Cancer
NCT06483048
Lumbar Vein Embolization for Chronic Headaches With Nutcracker Physiology
NCT06077747
Insulin and Insulin Pulses During Fasting
NCT06424015
Mapping of Electrical Properties in the Brain
NCT06470711
Family-Based Financial Incentives Intervention for Smoking Cessation
NCT06556433
Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic Cancer Undergoing Surgery
NCT06525740
Mayo Clinic Health System Northwest Wisconsin Integrated Maternal Postpartum Appointment Combination
NCT06395168
Adaptive Radiation Therapy (ART) Stereotactic Ablative Body Radiotherapy (SABR) for Primary Localized Prostate Cancer
NCT06325046
A Study of Oral Kavalactones Effect on Nurses
NCT06177535
Wisconsin Ginseng for Decreasing Cancer Related Fatigue
NCT06395441
Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume
NCT06195059
Deucravacitinib (BMS-986165) for Pityriasis Rubra Pilaris
NCT06444399
Ultrasound-Guided Core Needle Biopsy to Stage Urothelial Carcinoma of the Bladder (US UCB)
NCT07029256
Under-Resourced Adults With Chronic Pain eHealth Study
NCT06688864
Feasibility of Patient-Centered Home Care (PCHC) to Reduce Disparities in High-Risk Black Men (BM) With Prostate Cancer (CaP)
NCT06470750
Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor Therapy
NCT06401889
Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic Encephalopathy
NCT06425380
Remote Monitoring With Health-Coaching to Improve Quality of Life in Older Patients With Multiple Myeloma
NCT06145581
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 435 |
| Phase 2 | 386 |
| Phase 3 | 86 |
| Phase 4 | 166 |
Therapeutic Areas
What is open in the Mayo Clinic pipeline
544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).
Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).
Top condition: Healthy (36 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.