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NCT06434324 · ClinicalTrials.gov registry record · NA
Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in Empyema/Complicated Parapneumonic Effusion
A NA study of Pleural Infection, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06434324: Recruiting NA study of Pleural Infection, sponsored by Mayo Clinic.
NCT06434324 is a NA study of Pleural Infection that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06434324, a NA study of Pleural Infection, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to see if there is any benefit in adding saline irrigation through a chest tube to the standard course of treatment for people diagnosed or suspected of having a pleural space infection.
Primary Outcome
Number of intrapleural fibrinolytic doses to achieve adequate pleural space evacuation (defined as \<=2.5 cm separation between parietal and visceral pleural layers on bedside ultrasound or no more than small residual effusion on clinically-directed CT chest imaging).
Conditions Studied
Interventions
- PROCEDURE Saline Irrigation
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-03-29 |
| Est. Completion | 2026-05-04 |
| Phase | NA |
What NCT06434324 shows while recruiting
NCT06434324 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Pleural Infection appearing as the primary indexed condition, and to 1 intervention - of which Saline Irrigation is the first listed.
NCT06434324 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT06434324 about?
NCT06434324 is a clinical study titled "Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in Empyema/Complicated Parapneumonic Effusion". The purpose of this study is to see if there is any benefit in adding saline irrigation through a chest tube to the standard course of treatment for people diagnosed or suspected of having a pleural space infection.
What is the current status of trial NCT06434324?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-03-29. Estimated completion is 2026-05-04.
What conditions does trial NCT06434324 study?
This clinical trial studies the following conditions: Pleural Infection.
What interventions are being tested in trial NCT06434324?
The interventions under investigation include: Saline Irrigation (PROCEDURE).
Who is sponsoring clinical trial NCT06434324?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06434324 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pleural Infection
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06434324's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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