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NCT06693674 · ClinicalTrials.gov registry record · Phase 3

Effect of Sacubitril-Valsartan on Cardiac Structure and Function

A Phase 3 study of Congenital Heart Disease, sponsored by Mayo Clinic.

Recruiting
Registry status
Phase 3
Development phase
45
Enrollment target
1
Study location

NCT06693674 is a Phase 3 study of Congenital Heart Disease that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 45 participants, below the 473-participant average among 63 other Congenital Heart Disease trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06693674, a Phase 3 study of Congenital Heart Disease, is actively recruiting participants, sponsored by Mayo Clinic.

RECRUITING
Registry status
Phase 3
Development phase
45 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to compare changes in cardiac structure and function, biomarkers, and patient reported outcomes between adults with congenital heart disease (ACHD) randomized to angiotensin receptor-neprilysin inhibitor (ARNI) therapy vs placebo.

Conditions Studied

Congenital Heart Disease

Interventions

  • OTHER Placebo
  • DRUG Entresto Pill

Study Locations (1)

Minnesota

  • Mayo Clinic in Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2025-02-03
Est. Completion 2026-12
Phase Phase 3

Sponsor

Mayo Clinic

2,844 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06693674

The ClinicalTrials.gov registry entry for NCT06693674 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 473-participant average among 63 other Congenital Heart Disease trials with a reported enrollment target (90% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Congenital Heart Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06693674 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT06693674 about?

NCT06693674 is a clinical study titled "Effect of Sacubitril-Valsartan on Cardiac Structure and Function". The purpose of this study is to compare changes in cardiac structure and function, biomarkers, and patient reported outcomes between adults with congenital heart disease (ACHD) randomized to angiotensin receptor-neprilysin inhibitor (ARNI) therapy vs placebo.

What is the current status of trial NCT06693674?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 45 participants. The study started on 2025-02-03. Estimated completion is 2026-12.

What conditions does trial NCT06693674 study?

This clinical trial studies the following conditions: Congenital Heart Disease.

What interventions are being tested in trial NCT06693674?

The interventions under investigation include: Placebo (OTHER), Entresto Pill (DRUG).

Who is sponsoring clinical trial NCT06693674?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06693674 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.