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NCT06837857 · ClinicalTrials.gov registry record · Phase 2
Prescription Opioids, Brain Structure, and Cognition in Older Adults With Chronic Pain
A Phase 2 study of Pain, Chronic, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT06837857 is a Phase 2 study of Pain, Chronic that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 200 participants, below the 717-participant average among 48 other Pain, Chronic trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06837857, a Phase 2 study of Pain, Chronic, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine whether exposure to prescription opioids is associated with brain structural changes on magnetic resonance imaging (MRI), with the primary outcome of white matter integrity as measured by fractional anisotropy of the corpus callosum.
Conditions Studied
Interventions
- DRUG Opioid
- DRUG Opioid Placebo
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2025-04-16 |
| Est. Completion | 2029-12-31 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06837857
The ClinicalTrials.gov registry entry for NCT06837857 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 717-participant average among 48 other Pain, Chronic trials with a reported enrollment target (72% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Pain, Chronic appearing as the primary indexed condition, and to 2 interventions - of which Opioid is the first listed.
NCT06837857 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.
Frequently Asked Questions
What is clinical trial NCT06837857 about?
NCT06837857 is a clinical study titled "Prescription Opioids, Brain Structure, and Cognition in Older Adults With Chronic Pain". The purpose of this study is to determine whether exposure to prescription opioids is associated with brain structural changes on magnetic resonance imaging (MRI), with the primary outcome of white matter integrity as measured by fractional anisotropy of the corpus callosum.
What is the current status of trial NCT06837857?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2025-04-16. Estimated completion is 2029-12-31.
What conditions does trial NCT06837857 study?
This clinical trial studies the following conditions: Pain, Chronic.
What interventions are being tested in trial NCT06837857?
The interventions under investigation include: Opioid (DRUG), Opioid Placebo (DRUG).
Who is sponsoring clinical trial NCT06837857?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06837857 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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