Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 34 of 57

COMPLETED Phase 4

PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding

NCT02557672

COMPLETED NA

Familial Partial Lipodystrophy Study

NCT02858830

COMPLETED NA

Impact of Massage Therapy on the Quality of Life of Hospice Patients

NCT02880202

TERMINATED

Evaluation of Autonomic Function in Individuals With Cornelia de Lange Syndrome (CdLS)

NCT03113877

COMPLETED Phase 2

Hypofractionation Proton Beam Therapy With Concurrent Treatment of Prostate and Pelvic Nodes for Prostate Cancer

NCT02874014

COMPLETED NA

Robotic Surgery in the Seated Position for Benign and Malignant Lesions of the Head and Neck

NCT02792322

COMPLETED Phase 2

Ribociclib and Letrozole in Treating Patients With Relapsed ER Positive Ovarian, Fallopian Tube, Primary Peritoneal, or Endometrial Cancer

NCT02657928

COMPLETED NA

Prevention and Early Detection and Intervention of Post-Coronary Artery Bypass Grafting Surgery (CABG) Acute Kidney Injury (AKI)

NCT02838667

COMPLETED NA

Quality of Life Intervention for Patients Receiving Radiation Therapy for Advanced Cancer Treatment and Their Caregivers

NCT03094780

COMPLETED Early Phase 1

Impact of Continuous Positive Airway Pressure on Breathing Motion Amplitude

NCT02852473

COMPLETED Phase 1

Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and Frontotemporal Dementia

NCT02736695

COMPLETED Phase 1

Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery

NCT02730546

TERMINATED Phase 2

Addressing Post Cessation Weight Gain

NCT02412631

TERMINATED

Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma

NCT02613299

TERMINATED NA

MARK 1A Series: Percutaneous Microwave Ablation for Patients With Lung Tumor(s)

NCT02673021

COMPLETED

Stool Microbiome, Pathogens, and Infectious Agents Among Olympic and Elite Athletes

NCT02818413

COMPLETED NA

Exendin-9,39 and Satiety After Bariatric Surgery

NCT02779075

COMPLETED NA

Physical Activity in the Medical Workplace

NCT02794727

COMPLETED Phase 4

Sugammadex vs Placebo to Prevent Residual Neuromuscular Block

NCT02728726

TERMINATED NA

Spinal Stimulation During Exercise in Heart Failure

NCT02659202

COMPLETED Phase 2

A Trial of 15 Fraction vs 25 Fraction Pencil Beam Scanning Proton Radiotherapy After Mastectomy in Patients Requiring Regional Nodal Irradiation

NCT02783690

COMPLETED NA

Endoscopic Ultrasound Guided Fine Needle Biopsy (EUS-FNB-SC) Using a Novel Fork Needle

NCT02678442

COMPLETED Phase 2

Topical Composition Therapy (2013-MCN-333) for the Treatment of Melasma

NCT02730819

COMPLETED NA

Prospective Trial of Subcutaneous Versus Subpectoral 2-Staged Implant-Based Breast Reconstruction

NCT02775409

COMPLETED NA

Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean Delivery

NCT02789410

COMPLETED NA

Committed Actions for Successful Aging

NCT02702570

COMPLETED NA

Caring Hand Massage - an Intervention in Cancer Patients Undergoing Chemotherapy in an Outpatient Setting - a Pilot Study

NCT02742415

TERMINATED NA

Vascular Endothelial Function and Cardiac Resynchronization Response in Patients With Heart Failure

NCT02783716

TERMINATED NA

Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty

NCT02904993

TERMINATED

Efficacy of PET/MRI in Detecting Metastatic Disease in Endometrial Cancer

NCT02765698

COMPLETED Phase 1

Gossypol Acetic Acid With Lenalidomide and Dexamethasone in Treating Patients With Relapsed Symptomatic Multiple Myeloma

NCT02697344

COMPLETED NA

MC5-A Scrambler Therapy or TENS Therapy in Treating Patients With Chemotherapy-Induced Peripheral Neuropathy

NCT02722434

COMPLETED Phase 1

Lenalidomide and Dexamethasone With or Without Anakinra in Treating Patients With Early Stage Multiple Myeloma

NCT02492750

COMPLETED NA

Gut Microbiota Changes in Obese Individuals Undergoing Dedicated Lifestyle Modification Programs

NCT02855242

COMPLETED Phase 4

MUA to Treat Postoperative Stiffness After Total Knee Arthroplasty

NCT02739035

COMPLETED NA

Comparing The Outcome of Large-Diameter vs Small-Diameter Glenospheres in Primary Reverse Shoulder Arthroplasty

NCT02768597

COMPLETED Phase 1

Treatment of IgG4-Related Disease With Revlimid and Rituximab

NCT02705638

COMPLETED NA

Simulation and Cadaver Workshop for Medical Students

NCT03050281

COMPLETED NA

Weight Gain and Adipose Tissue

NCT02703766

COMPLETED NA

Impact of MayoExpertAdvisor on Provider Adherence

NCT02742545

COMPLETED NA

Exercise Preconditioning and Breast Cancer Cardiotoxicity

NCT02842658

COMPLETED NA

Biofeedback for Wheelchair Users

NCT02700178

TERMINATED Phase 2

Manage Diarrhea in Patients With Multiple Myeloma While Receiving Conditioning Chemotherapy for Autologous SCT

NCT02619812

TERMINATED

Immune Predictors of Response to Pembrolizumab Therapy in Stage IV Melanoma Patients

NCT02744209

TERMINATED

Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma

NCT02613312

TERMINATED

Mayo Clinic Foregut Surgery Report Card Questionnaire

NCT02708303

COMPLETED NA

Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use

NCT02680145

COMPLETED Phase 1

Hematopoietic Stem Cell Transplant Survivors Study

NCT02652052

COMPLETED Phase 1

Curcumin and Piperine in Reducing Inflammation for Ureteral Stent-Induced Symptoms in Patients With Cancer

NCT02598726

COMPLETED

A Study of Mucosal Sparing Proton Beam Therapy (PBT) in Resected Oropharyngeal Tumors

NCT02736786

← Previous Page 34 of 57 Next →

Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.