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NCT02557672 · ClinicalTrials.gov registry record · Phase 4
PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding
A Phase 4 study of Bleeding and Blood Loss, Surgical, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 4
- Development phase
- 106
- Enrollment target
- 1
- Study location
NCT02557672: Completed Phase 4 study of Bleeding and Blood Loss, Surgical, sponsored by Mayo Clinic.
NCT02557672 is a Phase 4 study of Bleeding and Blood Loss, Surgical that has completed, run by Mayo Clinic. The registered enrollment target is 106 participants, below the 1,480-participant average among 23 other Bleeding trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02557672, a Phase 4 study of Bleeding and Blood Loss, Surgical, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 106 participants
- Enrollment target
- 1
- Study location
Study Summary
This will be the first prospective randomized controlled clinical trial directly comparing Prothrombin Complex Concentrate (PCC) Compared to Fresh Frozen Plasma (FFP) for post cardiopulmonary bypass microvascular bleeding and factor-mediated coagulopathy. Is there a difference in bleeding and transfusion requirements in patients received PCC versus FFP?
Primary Outcome
The amount of chest tube drainage output from after surgery through midnight of the next day. As measured in mL.
Conditions Studied
Interventions
- DRUG Prothrombin complex concentrate (Human)
- BIOLOGICAL Fresh frozen plasma (FFP)
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 106 participants |
| Start Date | 2016-08 |
| Est. Completion | 2022-01 |
| Phase | Phase 4 |
What the finished NCT02557672 record still lists
NCT02557672 is an interventional study that assigns participants to a tested intervention. The registered 106 participants enrollment target is mid-sized for trials with a published cap, below the 1,480-participant average among 23 other Bleeding trials with a reported enrollment target (93% lower).
The record links to 5 conditions, with Bleeding appearing as the primary indexed condition, and to 2 interventions - of which Prothrombin complex concentrate (Human) is the first listed.
NCT02557672 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT02557672 about?
NCT02557672 is a clinical study titled "PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding". This will be the first prospective randomized controlled clinical trial directly comparing Prothrombin Complex Concentrate (PCC) Compared to Fresh Frozen Plasma (FFP) for post cardiopulmonary bypass microvascular bleeding and factor-mediated coagulopathy. Is there a difference in bleeding and transf...
What is the current status of trial NCT02557672?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 106 participants. The study started on 2016-08. Estimated completion is 2022-01.
What conditions does trial NCT02557672 study?
This clinical trial studies the following conditions: Bleeding, Blood Loss, Surgical, Cardiovascular Surgical Procedures, Prothrombin Complex Concentrates, Fresh Frozen Plasma.
What interventions are being tested in trial NCT02557672?
The interventions under investigation include: Prothrombin complex concentrate (Human) (DRUG), Fresh frozen plasma (FFP) (BIOLOGICAL).
Who is sponsoring clinical trial NCT02557672?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02557672 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Bleeding
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02557672's enrollment target sits among peer trials
106 19th of 23 higher than 5 of 23 other Bleeding trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Bleeding trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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