Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 35 of 57

COMPLETED Phase 2

The Effect of Bariatric Surgery on Metabolism, the Metabolome and Microbiome in Patients With Type 2 Diabetes

NCT02762708

COMPLETED

Gut Permeability Assessment in Celiac and Gluten Sensitive Children

NCT02690532

COMPLETED NA

Stress Management Intervention in Women's Heart Clinic, Heart SMART Program

NCT02670421

COMPLETED

Chronic Inflammation and Exercise Responsiveness

NCT02732509

COMPLETED Phase 1

Genetic Risk Estimation of Breast Cancer Prior to Preventive Medication Uptake

NCT02517593

COMPLETED

Advanced MR Imaging in Sarcoma Patients

NCT02705391

COMPLETED

SBRT for Oligometastatic Castration-Refractory Prostate Cancer

NCT02816983

TERMINATED Phase 1

Disulfiram and Chemotherapy in Treating Patients With Refractory Solid Tumors or Metastatic Pancreatic Cancer

NCT02671890

TERMINATED

A Clinical Test for the Treatment of Multifocal Lung Cancers Using Genome Sequencing

NCT02705404

COMPLETED Phase 2

Ibrutinib in Treating Minimal Residual Disease in Patients With Chronic Lymphocytic Leukemia After Front-Line Therapy

NCT02649387

TERMINATED Phase 1

TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid Tumors

NCT02650635

TERMINATED Phase 1

Everolimus and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

NCT02254239

COMPLETED

Quantitation of McArdle's Sign and Evaluation of Specificity for Multiple Sclerosis

NCT03122873

COMPLETED Phase 3

Metformin for the Prevention of Episodic Migraine (MPEM)

NCT02593097

COMPLETED

Evaluation of the Relationship Between Vaginal and Lower Urinary Tract Microbiomes and Infection After Hysterectomy

NCT02751073

COMPLETED Phase 1

Use of F-652 in Patients With Alcoholic Hepatitis

NCT02655510

COMPLETED NA

Patient Perception of Video Advance Care Planning

NCT02692950

COMPLETED NA

Adolescent Mental Health InSciEd Out

NCT02680899

TERMINATED Phase 3

IVIG in Patients With VGKC Ab Associated Autoimmune Epilepsy

NCT02697292

COMPLETED NA

Screening for Metabolic Problems in Mothers of Children With Autism and Typically Developing Children

NCT02674022

TERMINATED

Cardiotoxic Effects of Chemotherapy in Patients With Sarcomas: A Two and Three-dimensional Echocardiographic Speckle Tracking Imaging Study

NCT06511388

COMPLETED NA

Salvia Hispanica Seed in Reducing Risk of Disease Recurrence in Patients With Non-Hodgkin Lymphoma

NCT02652715

TERMINATED

Staging Procedures to Diagnose Malignant Pleural Mesothelioma

NCT02648763

COMPLETED NA

Spinal Cord Injury Epidural Stimulation

NCT02592668

COMPLETED NA

Enhancement of Contrast Opacification for Echocardiographic Imaging of the Right Heart and Shunts

NCT02661529

COMPLETED Phase 4

Perioperative Intravenous Lidocaine Infusion for Patients Undergoing Laparoscopic and Open Pancreatectomies

NCT02623803

COMPLETED Phase 1

Stem Cell Fistula Plug in Cryptoglandular Perianal Fistulas (MSC-AFP)

NCT02589119

COMPLETED

Esophageal Motility in Reflux Induced Cough

NCT02492126

COMPLETED Phase 1

Point-of-Care RBC Washing to Prevent Transfusion-Related Pulmonary Complications

NCT02094118

COMPLETED Early Phase 1

Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations

NCT02646319

COMPLETED Phase 1

Idasanutlin, Ixazomib Citrate, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma

NCT02633059

TERMINATED Phase 2

Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutation

NCT02634827

COMPLETED Phase 2

Pomalidomide, Ixazomib Citrate, and Dexamethasone in Treating Patients With Previously Treated Multiple Myeloma or Plasma Cell Leukemia

NCT02547662

COMPLETED Phase 2

Pilot Study of the Effect of Liraglutide on Weight Loss and Gastric Functions in Obesity

NCT02647944

COMPLETED NA

Effect of Cueing on Gluteus Maximus Recruitment

NCT02645188

COMPLETED NA

Reducing 30-day Readmissions in Patients With Heart Failure Through Pharmacist Discharge Medication Services

NCT02752997

COMPLETED

InBody Validation Study

NCT02635958

COMPLETED NA

Cytosponge and Dietary Therapy in EoE

NCT02599558

COMPLETED NA

The Role of Therapy for Muscle Tension Dysphagia

NCT02647931

COMPLETED Phase 3

A Study of Colesevelam in Fecal Incontinence

NCT02628626

COMPLETED

Objective Measure of Recovery After Outpatient Surgery

NCT02616406

COMPLETED NA

Use of a Shear Reduction Surface in Pre-hospital Transport

NCT02591641

COMPLETED

Bile Usefulness for Detecting IgG4-related Sclerosing Cholangitis

NCT02616705

COMPLETED Phase 4

IRB 14-009240, Does CEUS Positively Influence Selection of Biopsy Sites When Evaluating Transplant Kidneys?

NCT02625428

COMPLETED Early Phase 1

Osteoclast Inhibition and Bone Formation

NCT02554695

COMPLETED NA

A Minimally-Invasive Sponge on a String Device for Screening for Barrett's Esophagus

NCT02560623

COMPLETED NA

Peripheral Nerve Stimulation to Reduce Hypoxic Events

NCT02554110

COMPLETED NA

Club Fit: Physical Activity and Healthy Eating at an After School Program

NCT03189979

COMPLETED Phase 4

Corticosteroid/Ropivacaine Versus Corticosteroid/Saline Injections for Knee Osteoarthritis

NCT02576249

COMPLETED Phase 1

Root Coverage Using a Xenograph for Treatment of Gingival Recession

NCT02657395

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.