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NCT02789410 · ClinicalTrials.gov registry record · NA
Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean Delivery
A NA study, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 134
- Enrollment target
NCT02789410: Completed NA study, sponsored by Mayo Clinic.
NCT02789410 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 134 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02789410, a NA study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 134 participants
- Enrollment target
Study Summary
Intrathecal (IT) opioids are commonly administered with local anesthetic during spinal anesthesia for post-Cesarean delivery analgesia. Traditionally, IT morphine has been used but the use of IT hydromorphone is growing. A previous study has shown that the effective dose for postoperative analgesia in 90% patients (ED90) for both IT hydromorphone and IT morphine (NCT02009722). These doses were found to be 75 mcg for hydromorphone and 150 mcg for morphine. The current proposed study would compare the duration of analgesia of IT morphine vs IT hydromorphone after elective cesarean delivery. Additionally, the investigators will compare each drug with respect the incidence of nausea and pruritus.
Primary Outcome
Each patient will be interviewed by a member of the study team 24 hours after receiving their spinal anesthetic. Patients will be asked to rate their current level of pain on a Numeric Rating Scale (NRS) of 0 (no pain) to 10 (worst pain imaginable).
Interventions
- DRUG Hydromorphone
- DRUG Morphine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 134 participants |
| Start Date | 2016-05 |
| Est. Completion | 2018-03-15 |
| Phase | NA |
What the finished NCT02789410 record still lists
NCT02789410 is an interventional study that assigns participants to a tested intervention. The registered 134 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Hydromorphone is the first listed.
NCT02789410 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02789410 about?
NCT02789410 is a clinical study titled "Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean Delivery". Intrathecal (IT) opioids are commonly administered with local anesthetic during spinal anesthesia for post-Cesarean delivery analgesia. Traditionally, IT morphine has been used but the use of IT hydromorphone is growing. A previous study has shown that the effective dose for postoperative analgesia ...
What is the current status of trial NCT02789410?
This trial is currently completed. It is a NA study. The enrollment target is 134 participants. The study started on 2016-05. Estimated completion is 2018-03-15.
What interventions are being tested in trial NCT02789410?
The interventions under investigation include: Hydromorphone (DRUG), Morphine (DRUG).
Who is sponsoring clinical trial NCT02789410?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02789410's enrollment target sits among peer trials
134 728th of 2000 higher than 1,272 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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