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NCT02739035 · ClinicalTrials.gov registry record · Phase 4
MUA to Treat Postoperative Stiffness After Total Knee Arthroplasty
A Phase 4 study of Stiffness Following Total Knee Arthroplasty, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 4
- Development phase
- 130
- Enrollment target
- 16
- Study locations
NCT02739035: Completed Phase 4 study of Stiffness Following Total Knee Arthroplasty, sponsored by Mayo Clinic.
NCT02739035 is a Phase 4 study of Stiffness Following Total Knee Arthroplasty that has completed, run by Mayo Clinic. The registered enrollment target is 130 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (75% lower). The trial reports 16 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02739035, a Phase 4 study of Stiffness Following Total Knee Arthroplasty, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 130 participants
- Enrollment target
- 16
- Study locations
Study Summary
Compare the outcome following manipulation under anesthesia for stiffness in a randomized controlled fashion with one group receiving IV dexamethasone and oral celecoxib at the time of manipulation to a control group receiving manipulation alone. Outcomes will include pain, range of motion, as well as subjective outcome scores.
Primary Outcome
Knee range of motion after manipulation will be measured in degrees as the total arc of motion from maximum passive flexion to maximum passive extension.
Conditions Studied
Interventions
- DRUG Dexamethasone
- DRUG Celecoxib
Study Locations (16)
New York
- Hospital for Joint Diseases - New York
- Hospital for Special Surgery - New York
- New York - Presbyterian at Columbia University - New York
North Carolina
- OrthoCarolina - Charlotte
- Duke University Medical Ceter, Dept. of Orthopaedics - Durham
Ohio
- Cleveland Clinic - Cleveland
- Joint Implant Surgeons - New Albany
Pennsylvania
- Rothman Institute - Lansdale
- Aria 3B Orthopaedic Specialists - Philadelphia
Arkansas
- HipKnee Arkansas Foundation - Little Rock
Colorado
- Colorado Joint Replacement - Denver
Illinois
- Rush University Medical Center - Chicago
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2016-04 |
| Est. Completion | 2022-12 |
| Phase | Phase 4 |
What the finished NCT02739035 record still lists
NCT02739035 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (75% lower).
The record links to 1 condition, with Stiffness Following Total Knee Arthroplasty appearing as the primary indexed condition, and to 2 interventions - of which Dexamethasone is the first listed.
NCT02739035 lists 16 locations in 11 states (New York, North Carolina, Ohio).
Frequently Asked Questions
What is clinical trial NCT02739035 about?
NCT02739035 is a clinical study titled "MUA to Treat Postoperative Stiffness After Total Knee Arthroplasty". Compare the outcome following manipulation under anesthesia for stiffness in a randomized controlled fashion with one group receiving IV dexamethasone and oral celecoxib at the time of manipulation to a control group receiving manipulation alone. Outcomes will include pain, range of motion, as well...
What is the current status of trial NCT02739035?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 130 participants. The study started on 2016-04. Estimated completion is 2022-12.
What conditions does trial NCT02739035 study?
This clinical trial studies the following conditions: Stiffness Following Total Knee Arthroplasty.
What interventions are being tested in trial NCT02739035?
The interventions under investigation include: Dexamethasone (DRUG), Celecoxib (DRUG).
Who is sponsoring clinical trial NCT02739035?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02739035 being conducted?
This trial has 16 study locations across Arkansas, Colorado, Illinois, Minnesota, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02739035's enrollment target sits among peer trials
130 622nd of 2000 higher than 1,371 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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