Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 33 of 57

COMPLETED

Smartphone Twelve Lead Electrocardiogram Utility In ST-Elevation Myocardial Infarction

NCT03037229

COMPLETED NA

Preservation of Joint Function Using Postoperative Continuous Passive Motion (CPM) A Pilot Study

NCT01420887

COMPLETED NA

Ultramarathons and Impact of Phased Electromagnetic Field Therapy (PEMF)

NCT03333135

COMPLETED NA

Feasibility Trial of the Early Psychological Support for the Critically Ill

NCT02739022

COMPLETED

Mayo Clinic Cardiac Implantable Electronic Device MRI Registry

NCT02357082

COMPLETED NA

Platelet Rich Plasma During Radical Prostatectomy

NCT02957149

COMPLETED

Pharmacogenetic Testing in Children With Persistent Gastroesophageal Reflux Disease

NCT03005080

COMPLETED

Isolating and Testing Circulating Tumor DNA and Soluble Immune Markers During the Course of Treatment for Lung Cancer

NCT02410603

COMPLETED NA

Treatment of RLS/WED Symptoms Through Sensory Counter-stimulation

NCT03249779

COMPLETED NA

Stress Management and Resiliency Training (SMART) Integrated Into Treatment of Major Depression

NCT03275961

COMPLETED

The TOGETHER Project - Kidney RNA-seq Validation

NCT03874299

COMPLETED NA

Evaluation of a Tele-Rehabilitation Service Program

NCT02577276

COMPLETED NA

Direct Anterior vs. Anterolateral Approach for Hip Arthroplasty After Femoral Neck Fracture in the Senior Population

NCT02959320

COMPLETED

The TOGETHER Project - Kidney

NCT03873623

COMPLETED NA

Stories for Change: Digital Storytelling as a Tool for Engagement in Facilitated Discussion for Diabetes

NCT02969954

COMPLETED NA

Use of Peppermint Oil During Screening Colonoscopy to Improve Visibility

NCT03286764

COMPLETED Phase 4

Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty

NCT02876055

COMPLETED Phase 1

Treatment of Recurrent Clostridium Difficile Infection With RBX7455

NCT02981316

COMPLETED NA

Influence of Central Obesity on the Esophageal Epithelial Barrier

NCT02776982

COMPLETED NA

Animal Assisted Therapy Intervention for Hospitalized Patients in a Tertiary Care Center

NCT02959632

COMPLETED Phase 2

Self-management of Sedative Therapy by Ventilated Patients

NCT02819141

COMPLETED Early Phase 1

Ixazomib Citrate, Lenalidomide, and Dexamethasone in Treating Patients With POEMS Syndrome

NCT02921893

COMPLETED NA

Behavioral and Psychological Impact of Returning Breast Density Results to Latinas

NCT02910986

COMPLETED NA

Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections

NCT02951351

COMPLETED Phase 3

Evaluation of De-escalated Adjuvant Radiation Therapy for Human Papillomavirus (HPV)-Associated Oropharynx Cancer

NCT02908477

COMPLETED NA

Pediatric Anxiety Intervention With an Entertaining Video Game: Feasibility Study

NCT02713425

COMPLETED NA

Effect of Topical Phenylephrine 2.5% on EVP in Normal Human Eyes

NCT02965924

COMPLETED NA

Sleep Extension and Blood Pressure

NCT02929810

TERMINATED

Sleep and Activity Monitoring After Thoracic Surgery

NCT02927860

COMPLETED NA

LLLT for Reducing Waste Circumference and Weight

NCT02877004

COMPLETED

Characterization of the Neo-squamous Epithelial Barrier

NCT03077594

COMPLETED Phase 2

Pembrolizumab, Lenalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma Eligible for Stem Cell Transplant

NCT02880228

COMPLETED Phase 2

Ox Bile- Conjugated Bile Acids Sodium in Type II Diabetes Mellitus

NCT02871882

COMPLETED NA

SDM for Stroke Prevention in Atrial Fibrillation

NCT02905032

COMPLETED NA

Red Blood Cell Transfusion in the Ambulatory Setting: Impact on Home Functional Status

NCT02835937

COMPLETED Phase 4

Real Time Myocardial Perfusion Echocardiography for Coronary Allograft Vasculopathy

NCT02880137

COMPLETED NA

FDG PET/MRI Evaluation of Facet Joint Pain

NCT02921490

COMPLETED

Providing Personally Tailored Dietary Suggestions Using Individual Microbiome and Glycemic Index Response.

NCT02945514

COMPLETED Phase 3

Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled Trial

NCT02885636

COMPLETED

Self Digital Photography for Assessing Elbow Range of Motion

NCT02985788

COMPLETED

Epidemiology and Pathophysiology of Post-Infectious Functional GI Disorders

NCT03266068

COMPLETED

Electromyographic Assessment of the TetraGraph in Normal Volunteers

NCT02912039

COMPLETED NA

Home-based Health Management of Chronic Obstructive Lung Disease (COPD) Patients

NCT02999685

COMPLETED NA

Use of 31P MRS to Assess Brain NAD+ in Healthy Current and Former Collegiate Athletes

NCT02721537

TERMINATED

Human Mesenchymal Stem Cells in the Synovial Fluid of the Hip

NCT02941666

TERMINATED Phase 1

Positron Emission Tomography (PET) Imaging Studies With NIS Reporter

NCT02907073

TERMINATED Phase 2

Efficacy Study of Acetazolamide Versus Diazepam in Continuous Spike and Wave/Landau-Kleffner Syndrome

NCT02904265

COMPLETED NA

Shared Decision Making in Patients With Thyroid Nodules

NCT02878044

COMPLETED

Two Cancers, One Gene. Why Some People in Families Develop Melanoma or Pancreas Cancer, While Still Others Never Develop Cancer.

NCT03174574

COMPLETED NA

Developing and Implementing Asthma-Guidance and Prediction System (a-GPS) for Better Asthma Management

NCT02865967

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.