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NCT02598726 · ClinicalTrials.gov registry record · Phase 1
Curcumin and Piperine in Reducing Inflammation for Ureteral Stent-Induced Symptoms in Patients With Cancer
A Phase 1 study of Pain and Malignant Neoplasm, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 9
- Enrollment target
- 1
- Study location
NCT02598726: Completed Phase 1 study of Pain and Malignant Neoplasm, sponsored by Mayo Clinic.
NCT02598726 is a Phase 1 study of Pain and Malignant Neoplasm that has completed, run by Mayo Clinic. The registered enrollment target is 9 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02598726, a Phase 1 study of Pain and Malignant Neoplasm, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 9 participants
- Enrollment target
- 1
- Study location
Study Summary
This pilot phase I trial studies the side effects and best dose of curcumin when given together with piperine (piperine extract \[standardized\]) in reducing inflammation for ureteral stent-induced symptoms in patients with cancer. Curcumin is a spice similar to turmeric and works by decreasing the chemical moderators that produce inflammation in the body. Piperine is pepper and works by increasing the amount of curcumin available in the body when taken with curcumin. Giving curcumin together with piperine may reduce inflammation and discomfort from a ureteric stent in older patients with cancer.
Primary Outcome
Examined in an exploratory and hypothesis-generating fashion. The number and severity of all adverse events (overall, by dose-level, and by tumor type) will be tabulated and summarized in this patient population. The grade 2+ adverse events will also be described and summarized in a similar fashion.
Conditions Studied
Interventions
- OTHER Quality-of-Life Assessment
- OTHER Laboratory Biomarker Analysis
- DRUG Curcumin
- DIETARY_SUPPLEMENT Piperine Extract (Standardized)
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2016-03-01 |
| Est. Completion | 2018-09-19 |
| Phase | Phase 1 |
What the finished NCT02598726 record still lists
NCT02598726 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (97% lower).
The record links to 4 conditions, with Pain appearing as the primary indexed condition, and to 4 interventions - of which Quality-of-Life Assessment is the first listed.
NCT02598726 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT02598726 about?
NCT02598726 is a clinical study titled "Curcumin and Piperine in Reducing Inflammation for Ureteral Stent-Induced Symptoms in Patients With Cancer". This pilot phase I trial studies the side effects and best dose of curcumin when given together with piperine (piperine extract \[standardized\]) in reducing inflammation for ureteral stent-induced symptoms in patients with cancer. Curcumin is a spice similar to turmeric and works by decreasing the ...
What is the current status of trial NCT02598726?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2016-03-01. Estimated completion is 2018-09-19.
What conditions does trial NCT02598726 study?
This clinical trial studies the following conditions: Pain, Malignant Neoplasm, Urinary Urgency, Bladder Spasm.
What interventions are being tested in trial NCT02598726?
The interventions under investigation include: Quality-of-Life Assessment (OTHER), Laboratory Biomarker Analysis (OTHER), Curcumin (DRUG), Piperine Extract (Standardized) (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT02598726?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02598726 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02598726's enrollment target sits among peer trials
9 368th of 374 higher than 4 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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