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NCT02598726 · ClinicalTrials.gov registry record · Phase 1

Curcumin and Piperine in Reducing Inflammation for Ureteral Stent-Induced Symptoms in Patients With Cancer

A Phase 1 study of Pain and Malignant Neoplasm, sponsored by Mayo Clinic.

Completed
Registry status
Phase 1
Development phase
9
Enrollment target
1
Study location

NCT02598726 is a Phase 1 study of Pain and Malignant Neoplasm that has completed, run by Mayo Clinic. The registered enrollment target is 9 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02598726, a Phase 1 study of Pain and Malignant Neoplasm, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 1
Development phase
9 participants
Enrollment target
1
Study location

Study Summary

This pilot phase I trial studies the side effects and best dose of curcumin when given together with piperine (piperine extract \[standardized\]) in reducing inflammation for ureteral stent-induced symptoms in patients with cancer. Curcumin is a spice similar to turmeric and works by decreasing the chemical moderators that produce inflammation in the body. Piperine is pepper and works by increasing the amount of curcumin available in the body when taken with curcumin. Giving curcumin together with piperine may reduce inflammation and discomfort from a ureteric stent in older patients with cancer.

Interventions

  • OTHER Quality-of-Life Assessment
  • OTHER Laboratory Biomarker Analysis
  • DRUG Curcumin
  • DIETARY_SUPPLEMENT Piperine Extract (Standardized)

Study Locations (1)

Minnesota

  • Mayo Clinic - Rochester

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2016-03-01
Est. Completion 2018-09-19
Phase Phase 1

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT02598726

The ClinicalTrials.gov registry entry for NCT02598726 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 304-participant average among 374 other Pain trials with a reported enrollment target (97% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Pain appearing as the primary indexed condition, and to 4 interventions - of which Quality-of-Life Assessment is the first listed.

NCT02598726 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT02598726 about?

NCT02598726 is a clinical study titled "Curcumin and Piperine in Reducing Inflammation for Ureteral Stent-Induced Symptoms in Patients With Cancer". This pilot phase I trial studies the side effects and best dose of curcumin when given together with piperine (piperine extract \[standardized\]) in reducing inflammation for ureteral stent-induced symptoms in patients with cancer. Curcumin is a spice similar to turmeric and works by decreasing the ...

What is the current status of trial NCT02598726?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2016-03-01. Estimated completion is 2018-09-19.

What conditions does trial NCT02598726 study?

This clinical trial studies the following conditions: Pain, Malignant Neoplasm, Urinary Urgency, Bladder Spasm.

What interventions are being tested in trial NCT02598726?

The interventions under investigation include: Quality-of-Life Assessment (OTHER), Laboratory Biomarker Analysis (OTHER), Curcumin (DRUG), Piperine Extract (Standardized) (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT02598726?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02598726 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.