Johns Hopkins University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Johns Hopkins University sits in the top decile of US sponsors by registered trial count (#14 of 15,742 sponsors by registered trial count).

1,448 total trials 250 currently recruiting 943 completed early-phase tilt top decile by trial count

Johns Hopkins University: 1,448 sponsored US clinical trials, 250 recruiting.

Johns Hopkins University sponsors 1,448 registered US clinical trials on ClinicalTrials.gov, 250 of them currently recruiting, and 943 completed. 125 of these trials are in Phase 3-4 (later-stage) and 399 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 15 trials.

Top-decile sponsor footprint

Johns Hopkins University ranks in the top decile of sponsors by registered trial count (#14 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 52/100

943 of 1,108 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (85.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,448 total, page 23 of 29

COMPLETED Phase 4

Trial of Carvedilol in Alzheimer's Disease

NCT01354444

COMPLETED

The Johns Hopkins Transplant Infectious Diseases Prospective Cohort Study

NCT01986504

COMPLETED Phase 4

Safety Study of Analgesia After Craniotomy Surgery With End Tidal (ET) Carbon Dioxide (CO2) Monitoring

NCT01327677

COMPLETED

Registry of Non-primary Angioplasty at Hospitals Without Surgery On-site

NCT02137980

COMPLETED NA

Multi-Method Health System Quality Improvement Intervention to Reduce Hypertension Disparities

NCT01566864

COMPLETED NA

A Study of Novel Smoking Cessation Interventions in Current and Former Injection Drug Users

NCT01334736

COMPLETED NA

Effect of Sedation on Diagnostic Injections

NCT01472835

COMPLETED

The Detection of Glaucoma Using Pupillography

NCT01462526

COMPLETED NA

Internet-Based Intervention to Improve Mental Health Outcomes for Abused Women

NCT01312103

COMPLETED NA

Treatment of Acne Keloidalis Nuchae (Razor Bumps Behind the Neck) Using UV Light Therapy

NCT01328080

COMPLETED NA

Nutrition Knowledge for Spanish-speaking Parents

NCT01296945

COMPLETED Phase 1

Effects of Dronabinol (Oral THC) on Cannabis Use

NCT01394185

COMPLETED Phase 4

Interferon Alfa Sensitivity in HIV/HCV Persons Before and After HIV Meds

NCT01285050

COMPLETED NA

Meaningful Use of Technology to Improve Health Care Delivery

NCT01641380

COMPLETED Phase 1

Combined Effects of Alcohol and Caffeine

NCT01289561

COMPLETED NA

The Respiratory Protection Effectiveness Clinical Trial

NCT01249625

COMPLETED Phase 2

Cognitive Stimulation

NCT01271413

COMPLETED Phase 2

Ondansetron, Alcohol Use, and Alcohol-Related Symptoms In HIV+ Persons

NCT01254877

COMPLETED NA

Pharmacokinetics of Vitamin D in Multiple Sclerosis and in Health

NCT01667796

COMPLETED NA

Impact of Information Prescriptions on Medication Adherence in Emergency Department (ED) Patients

NCT01174706

COMPLETED Phase 1

Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder

NCT01354314

COMPLETED Phase 3

Mouse Allergen and Asthma Intervention Trial

NCT01251224

COMPLETED Phase 2

Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and Wrinkles

NCT01283464

TERMINATED NA

CNS Growth Factors Release and Changes in the Inflammatory Environment in Response to Electrical Stimulation in Subjects With Inflammatory Myelopathies

NCT01440452

TERMINATED

Benefits of Post-Pyloric Feeding Tubes in Critically Ill Patients

NCT01343316

TERMINATED NA

Dietary Interventions in Asthma Treatment: Sprouts Study

NCT01183923

COMPLETED NA

Lifestyle Interventions for Seniors With Apnea

NCT01422863

COMPLETED Phase 1

Medications Development for Drug Abuse Disorders

NCT01188421

COMPLETED Phase 2

Effects of Mental Stimulation in Patients With Mild Cognitive Impairment

NCT01212692

COMPLETED Phase 1

Pharmacokinetic Interaction Study of Efavirenz and American Ginseng in Healthy Volunteers

NCT01136928

COMPLETED Phase 2

Broccoli Sprout Extracts Trial to See if NRF2 is Enhanced by Sulforaphane Treatment in Patients With COPD

NCT01335971

COMPLETED NA

Trial of Ascertaining Individual Preferences for Loved One's Role in End-of-Life

NCT01160367

COMPLETED NA

Yoga for Persons With Severe Visual Impairment

NCT01366677

COMPLETED NA

Cardiovascular Disease Education and Problem-Solving Training in People With Type 2 Diabetes

NCT00964587

TERMINATED Phase 1

Positron Emission Tomography (PET) Imaging of Glial Activation in Psychotic Disease States

NCT03257592

COMPLETED NA

Evaluating Three Methods for Helping Syringe Exchangers Begin Methadone Maintenance

NCT01142986

COMPLETED NA

Confocal Endomicroscopy for Improved Diagnosis of Barrett's Esophagus and Early Esophageal Cancer(CEBE Study)

NCT01124214

COMPLETED

Physiology of Vestibular Dysfunction and Clinical Implications

NCT01383642

COMPLETED Phase 1

A Within Subject Comparison of Opioid Withdrawal in Opioid Dependent Individuals

NCT01136356

COMPLETED NA

Case Management Study for Postpartum Depression and Intimate Partner Violence

NCT00560027

COMPLETED Phase 2

Covered CP Stents for the Prevention or Treatment of Aortic Wall Injury Associated With Coarctation of the Aorta

NCT01278303

COMPLETED

Assessing Cerebral Blood Flow Autoregulation During Surgery in the Head-up Position

NCT01225185

COMPLETED NA

Conservative Therapy Versus Epidural Steroids for Cervical Radiculopathy

NCT01144923

COMPLETED Phase 1

Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse

NCT01137890

TERMINATED NA

Baerveldt Plate Area Comparison (BPAC)

NCT01159314

TERMINATED NA

Tools to Optimize Patient Presentation After Onset of Exudative Age-Related Macular Degeneration (AMD)

NCT01337414

COMPLETED

Personalized Risk Identification and Management for Arrhythmias and Heart Failure by ECG and MRI

NCT01353131

TERMINATED

Prospective Randomized Trial of Anterograde Single Balloon Versus Spirus Enteroscopy

NCT01853241

COMPLETED Phase 1

Pharmacokinetics, Safety and Tolerability of Escalating Rifapentine Doses in Healthy Volunteers

NCT01162486

COMPLETED Phase 2

Lexapro for the Treatment of Traumatic Brain Injury (TBI) Depression & Other Psychiatric Conditions

NCT01368432

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Phase Distribution

PhaseTrial count
Phase 1 201
Phase 2 198
Phase 3 44
Phase 4 81

What is open in the Johns Hopkins University pipeline

250 recruiting of 1,448 indexed (17% open); 943 completed (65%).

Phase mix: 125 late (III/IV) vs 399 early (I/II) (early-phase heavy).

Top condition: Hypertension (15 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Johns Hopkins University: open-pipeline peers nationwide

Peers matched on 1,448 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Johns Hopkins University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Johns Hopkins UniversityUniversity of PennsylvaniaYale UniversityWashington University School of MedicineNovartis PharmaceuticalsSeattle Children's HospitalHunter College of City University of New YorkOchsner Health SystemVirginia Polytechnic Institute and State University
Johns Hopkins University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Johns Hopkins University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,448 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Johns Hopkins University page

1,448 registered trials is a research-attention snapshot, not an endorsement of Johns Hopkins University or any single study.

  • 250 of Johns Hopkins University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Hypertension is the condition Johns Hopkins University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Hypertension trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Johns Hopkins University pipeline card: 1,448 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.