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NCT01124214 · ClinicalTrials.gov registry record · NA
Confocal Endomicroscopy for Improved Diagnosis of Barrett's Esophagus and Early Esophageal Cancer(CEBE Study)
A NA study of Barrett's Esophagus, Esophageal Intraepithelial Neoplasia, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 68
- Enrollment target
- 4
- Study locations
NCT01124214 is a NA study of Barrett's Esophagus, Esophageal Intraepithelial Neoplasia that has completed, run by Johns Hopkins University. The registered enrollment target is 68 participants. The trial reports 4 study locations across 4 states.
The verdict
NCT01124214, a NA study of Barrett's Esophagus, Esophageal Intraepithelial Neoplasia, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 68 participants
- Enrollment target
- 4
- Study locations
Study Summary
Endomicroscopy (EM) can improve the diagnosis Barrett's esophagus (BE) and some early esophageal cancers (Intra Epithelial Neoplasia (IEN)). EM provides optical biopsies comparable to standard histology. Specifically, EM allows targeted biopsy rather than random mucosal biopsy during routine endoscopic surveillance of BE or evaluation EIN, which will improve the diagnostic yield of mucosal samples for BE IEN. Furthermore, when combined with high resolution endoscopy, EM may improve the overall in vivo detection of IEN in lesions as well as flat mucosa. EM will provide accurate place and size of IEN which will impact the physician's decision to biopsy or perform endoscopic mucosal resection (EMR). This could potentially minimize the number of unnecessary biopsies and as well as enable the physician to perform EMR at the time of the initial examination, rather than delaying endoscopic treatment after the pathology is available. This study is important because it will validate single center studies supporting the routine use of EM for screening and surveillance of BE.
Conditions Studied
Interventions
- PROCEDURE endomicroscopy
Study Locations (4)
Massachusetts
- Massachusetts General Hospital - Boston
New York
- Mount Sinai School of Medicine - New York
Pennsylvania
- University of Pennsylvania Medical Institution - Philadelphia
Other
- Johannes Gutenberg - University of Mainz - Mainz
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2010-07 |
| Est. Completion | 2013-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01124214
The ClinicalTrials.gov registry entry for NCT01124214 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 68 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Barrett's Esophagus, Esophageal Intraepithelial Neoplasia appearing as the primary indexed condition, and to 1 intervention - of which endomicroscopy is the first listed.
NCT01124214 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Massachusetts, New York, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT01124214 about?
NCT01124214 is a clinical study titled "Confocal Endomicroscopy for Improved Diagnosis of Barrett's Esophagus and Early Esophageal Cancer(CEBE Study)". Endomicroscopy (EM) can improve the diagnosis Barrett's esophagus (BE) and some early esophageal cancers (Intra Epithelial Neoplasia (IEN)). EM provides optical biopsies comparable to standard histology. Specifically, EM allows targeted biopsy rather than random mucosal biopsy during routine endosco...
What is the current status of trial NCT01124214?
This trial is currently completed. It is a NA study. The enrollment target is 68 participants. The study started on 2010-07. Estimated completion is 2013-06.
What conditions does trial NCT01124214 study?
This clinical trial studies the following conditions: Barrett's Esophagus, Esophageal Intraepithelial Neoplasia.
What interventions are being tested in trial NCT01124214?
The interventions under investigation include: endomicroscopy (PROCEDURE).
Who is sponsoring clinical trial NCT01124214?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01124214 being conducted?
This trial has 4 study locations across Massachusetts, New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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