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NCT01183923 · ClinicalTrials.gov registry record · NA
Dietary Interventions in Asthma Treatment: Sprouts Study
A NA study, sponsored by Johns Hopkins University.
- Terminated
- Registry status
- NA
- Development phase
- 1
- Enrollment target
NCT01183923: Clinical Trial NA study, sponsored by Johns Hopkins University.
NCT01183923 is a NA study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 1 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01183923, a NA study, was terminated before completion, sponsored by Johns Hopkins University.
- TERMINATED
- Registry status
- NA
- Development phase
- 1 participants
- Enrollment target
Study Summary
Sulforaphane (SFN) is a naturally occurring isothiocyanate that is a potent inducer of Phase II enzymes which play a critical role in preventing oxidative stress (via activation of Nrf2). Broccoli sprouts (BS) contain the richest source of SFN. The main objectives of this study are to test the effect of broccoli sprouts (BS) on biomarkers of oxidative stress (OS), inflammation, basophil activation, and clinical outcomes in mouse allergen-induced asthma by (1) determining if BS improves lung function and airways symptom responses in mouse-sensitized adults with asthma undergoing environmental mouse allergen challenge (EMAC), (2) examining the effect of BS on OS, inflammation, and basophil activation, and (3) examining the effect of BS on changes in OS, inflammation, and basophil activation after EMAC.
Primary Outcome
The percentage change in FEV1 from the pre-challenge FEV1 value over the 1 hour mouse chamber exposure.
Interventions
- OTHER Broccoli Sprouts
- OTHER Alfalfa Sprouts
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2010-11 |
| Est. Completion | 2012-02-06 |
| Phase | NA |
Why NCT01183923 stopped before completion
NCT01183923 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Broccoli Sprouts is the first listed.
NCT01183923 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01183923 about?
NCT01183923 is a clinical study titled "Dietary Interventions in Asthma Treatment: Sprouts Study". Sulforaphane (SFN) is a naturally occurring isothiocyanate that is a potent inducer of Phase II enzymes which play a critical role in preventing oxidative stress (via activation of Nrf2). Broccoli sprouts (BS) contain the richest source of SFN. The main objectives of this study are to test the effe...
What is the current status of trial NCT01183923?
This trial is currently terminated. It is a NA study. The enrollment target is 1 participants. The study started on 2010-11. Estimated completion is 2012-02-06.
What interventions are being tested in trial NCT01183923?
The interventions under investigation include: Broccoli Sprouts (OTHER), Alfalfa Sprouts (OTHER).
Who is sponsoring clinical trial NCT01183923?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01183923's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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