Johns Hopkins University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Johns Hopkins University sits in the top decile of US sponsors by registered trial count (#14 of 15,742 sponsors by registered trial count).

1,448 total trials 250 currently recruiting 943 completed early-phase tilt top decile by trial count

Johns Hopkins University: 1,448 sponsored US clinical trials, 250 recruiting.

Johns Hopkins University sponsors 1,448 registered US clinical trials on ClinicalTrials.gov, 250 of them currently recruiting, and 943 completed. 125 of these trials are in Phase 3-4 (later-stage) and 399 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 15 trials.

Top-decile sponsor footprint

Johns Hopkins University ranks in the top decile of sponsors by registered trial count (#14 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 52/100

943 of 1,108 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (85.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,448 total, page 18 of 29

COMPLETED Phase 1

Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin

NCT02592954

COMPLETED NA

Dietary Treatments for Cognitive Impairment in Older Adults

NCT02521818

COMPLETED Phase 1

Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain

NCT02372591

COMPLETED NA

Efficacy of Web-Based Social-Cognitive Interventions in Right Hemisphere Stroke and Frontotemporal Dementia

NCT02506036

COMPLETED

Tissue Repository for Studies of Myasthenia Gravis

NCT02902536

COMPLETED NA

CHAMPS Study: Chronic HepAtitis C Management to ImProve OutcomeS

NCT02402218

COMPLETED NA

Effectiveness of a Safety App to Respond to Dating Violence for College Women and Their Friends

NCT02236663

COMPLETED Phase 1

Open-label Study of Liothyronine in MS

NCT02506751

COMPLETED NA

EMPower: Electronic Media Powering Positive Health Changes in Youth

NCT02444689

COMPLETED NA

Sleep Apnea and Obesity Affects on Morphine Pharmacokinetics

NCT02732795

TERMINATED NA

PReventing the EffectS of Intubation on DEglutition

NCT02442102

TERMINATED NA

Randomized, Split-body, Single-blinded Clinical Trial of NB-UVB Treatment for Vitiligo

NCT02506101

TERMINATED NA

Study To Understand Fall Reduction and Vitamin D in You

NCT02166333

COMPLETED Phase 1

BDPP Treatment for Mild Cognitive Impairment (MCI) and Prediabetes or Type 2 Diabetes Mellitus (T2DM)

NCT02502253

TERMINATED NA

Surgical Application of Vac Dressings In Obese Patients to Reduce Wound Complications

NCT02461433

COMPLETED NA

Health Literacy Intervention for African Americans With Diabetes

NCT03925948

COMPLETED

G-POEM for Treatment of Refractory Gastroparesis

NCT02732821

COMPLETED NA

Aging, Cognition, and Hearing Evaluation in Elders Study

NCT02412254

COMPLETED NA

Per Oral Endoscopic Myotomy (POEM) for Esophagogastric Junction Outflow Obstruction (EGOO)

NCT01942018

COMPLETED NA

Study to Enhance Motor Acute Recovery With Intensive Training After Stroke

NCT02292251

TERMINATED Phase 1

EPOgen and Restrictive Transfusions in Patients Undergoing Cardiac Surgery (EPORT)

NCT02802592

COMPLETED Phase 2

A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans

NCT02360371

COMPLETED Phase 1

PET Imaging Study to Evaluate the mGlu5r Occupancy Following ADX48621 (Dipraglurant) Administration

NCT02447640

COMPLETED NA

Clinical Utility of Rapid CT/NG Testing in the ED

NCT02200224

COMPLETED NA

Take Charge of Burn Pain

NCT02661724

COMPLETED

Comparison of Patient Centered Outcomes for People With Sickle Cell Disease in the Acute Care Setting

NCT02411396

COMPLETED NA

Education Bundle to Decrease Patient Refusal of VTE Prophylaxis

NCT02402881

COMPLETED NA

Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Epithelium

NCT02534233

TERMINATED NA

Cardiogoniometry for Detecting Coronary Artery Disease by CT Angiography

NCT02725671

COMPLETED NA

Improving Patient-Centered Care Delivery Among Patients With Chronic Obstructive Pulmonary Disease

NCT02036294

COMPLETED NA

Comprehensive Home-based Dementia Care Coordination for Medicare-Medicaid Dual Eligibles in Maryland

NCT02395731

COMPLETED NA

Medium Chain Triglycerides as an Adjunct to the Modified Atkins Diet for Women With Catamenial Epilepsy

NCT02426047

COMPLETED Phase 2

Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Depression & Other Neuropsychiatric Symptoms After Traumatic Brain Injury (TBI)

NCT02367521

COMPLETED Phase 1

Laboratory Studies on Oxytocin for Treatment of Alcohol Use Disorder

NCT02407340

COMPLETED Phase 1

Effects of Psilocybin-facilitated Experience on the Psychology and Effectiveness of Professional Leaders in Religion

NCT02243813

TERMINATED NA

Cell-Based Approaches For Modeling and Treating Ataxia-Telangiectasia

NCT02246491

TERMINATED NA

Bovine Carotid Artery Biologic Graft and Expanded Polytetrafluoroethylene for Permanent Hemodialysis Access

NCT03300024

COMPLETED NA

Evaluation of a Tracheostomy Tube That Enables Communication

NCT02018562

TERMINATED Phase 1

Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.

NCT02321566

TERMINATED NA

Use of Preemptive Pudendal Nerve Block Prior to Hydrodistention for the Treatment of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS)

NCT02517996

TERMINATED

Pro-permeability and Pro-fibrosis Factors in the Aqueous of Patients With Retinal Diseases

NCT02688309

COMPLETED Phase 3

Efficacy of Botulinum Toxin In Scleroderma-Associated Raynaud's Syndrome

NCT02165111

COMPLETED Early Phase 1

Does Oral Acetaminophen Lower Intraocular Pressure?

NCT02366065

COMPLETED NA

Evaluation of a Computerized Opioid Overdose Prevention Program

NCT02040077

COMPLETED NA

POEM Anterior Versus Posterior Approach

NCT02454335

COMPLETED

ReNEW Clinic Cohort Study

NCT03816462

COMPLETED Phase 2

Inflammation and Coronary Endothelial Function

NCT02366091

COMPLETED NA

Hyperglycemic Profiles in Obstructive Sleep Apnea: Effects of PAP Therapy

NCT02454153

COMPLETED

Predictive Factors for LBP Interventional Treatment Outcomes

NCT02329951

COMPLETED

The Natural History of the Progression of Atrophy Secondary to Stargardt Disease Type 4: PROM1-Related Macular Dystrophy

NCT02410122

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Phase Distribution

PhaseTrial count
Phase 1 201
Phase 2 198
Phase 3 44
Phase 4 81

What is open in the Johns Hopkins University pipeline

250 recruiting of 1,448 indexed (17% open); 943 completed (65%).

Phase mix: 125 late (III/IV) vs 399 early (I/II) (early-phase heavy).

Top condition: Hypertension (15 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Johns Hopkins University: open-pipeline peers nationwide

Peers matched on 1,448 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Johns Hopkins University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Johns Hopkins UniversityUniversity of PennsylvaniaYale UniversityWashington University School of MedicineNovartis PharmaceuticalsSeattle Children's HospitalHunter College of City University of New YorkOchsner Health SystemVirginia Polytechnic Institute and State University
Johns Hopkins University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Johns Hopkins University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,448 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Johns Hopkins University page

1,448 registered trials is a research-attention snapshot, not an endorsement of Johns Hopkins University or any single study.

  • 250 of Johns Hopkins University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Hypertension is the condition Johns Hopkins University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Hypertension trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Johns Hopkins University pipeline card: 1,448 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.