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NCT02592954 · ClinicalTrials.gov registry record · Phase 1
Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin
A Phase 1 study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- Phase 1
- Development phase
- 5
- Enrollment target
NCT02592954: Completed Phase 1 study, sponsored by Johns Hopkins University.
NCT02592954 is a Phase 1 study that has completed, run by Johns Hopkins University. The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02592954, a Phase 1 study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
Adult participants will apply a broccoli sprout extract-jojoba oil compound to one arm every night under occlusion for 1 week. Jojoba oil alone will be applied to the other arm. At the end of 1 week, a 6mm punch biopsy will be taken from both arms and analyzed via polymerase chain reaction (PCR) and immunohistochemistry for differences in various skin proteins.
Primary Outcome
Immunohistochemistry of protein levels of keratin 1, keratin 5, keratin 10, keratin 14, keratin 16, keratin 17, and Nrf2
Interventions
- DRUG Jojoba oil with broccoli sprout extract
- DRUG Jojoba oil (placebo)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2015-09 |
| Est. Completion | 2016-12 |
| Phase | Phase 1 |
What the finished NCT02592954 record still lists
NCT02592954 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 2 interventions - of which Jojoba oil with broccoli sprout extract is the first listed.
NCT02592954 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02592954 about?
NCT02592954 is a clinical study titled "Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin". Adult participants will apply a broccoli sprout extract-jojoba oil compound to one arm every night under occlusion for 1 week. Jojoba oil alone will be applied to the other arm. At the end of 1 week, a 6mm punch biopsy will be taken from both arms and analyzed via polymerase chain reaction (PCR) and...
What is the current status of trial NCT02592954?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2015-09. Estimated completion is 2016-12.
What interventions are being tested in trial NCT02592954?
The interventions under investigation include: Jojoba oil with broccoli sprout extract (DRUG), Jojoba oil (placebo) (DRUG).
Who is sponsoring clinical trial NCT02592954?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02592954's enrollment target sits among peer trials
5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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