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NCT04728295 · ClinicalTrials.gov registry record · NA
Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)
A NA study of Parkinson Disease, sponsored by InSightec.
- Active
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 9
- Study locations
NCT04728295: Active NA study of Parkinson Disease, sponsored by InSightec.
NCT04728295 is a NA study of Parkinson Disease that is active but no longer recruiting, run by InSightec. The registered enrollment target is 50 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The trial reports 9 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04728295, a NA study of Parkinson Disease, is active but no longer recruiting, sponsored by InSightec.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 9
- Study locations
Study Summary
Evaluate the Safety and Effectiveness of Staged Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD).
Primary Outcome
OFF-medication, Upper + Lower Extremity motor score from the MDS-UPDRS Part III comparing Month 3 post Bilateral treatment to Baseline. Lower score on the scale means a better outcome.
Conditions Studied
Interventions
- DEVICE Exablate 4000
Study Locations (9)
New York
- New York University Langone - New York
- Weill Cornell Medicine - New York
Other
- Neurology, Hospital Universitario HM Puerta del Sur (HM CINAC) - Madrid
- Clínica Universidad de Navarra - Pamplona
California
- Stanford - Palo Alto
Florida
- Delray Medical Center - Delray Beach
Illinois
- Rush University Medical Center - Chicago
Maryland
- University of Maryland, Baltimore - Baltimore
Changhua County
- Chang Bing Show Chwan Memorial Hospital - Lugang
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2021-05-14 |
| Est. Completion | 2028-12-01 |
| Phase | NA |
What the registry record for NCT04728295 still lists
NCT04728295 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Parkinson Disease appearing as the primary indexed condition, and to 1 intervention - of which Exablate 4000 is the first listed.
NCT04728295 lists 9 locations in 7 states (New York, Other, California).
Frequently Asked Questions
What is clinical trial NCT04728295 about?
NCT04728295 is a clinical study titled "Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)". Evaluate the Safety and Effectiveness of Staged Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD).
What is the current status of trial NCT04728295?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2021-05-14. Estimated completion is 2028-12-01.
What conditions does trial NCT04728295 study?
This clinical trial studies the following conditions: Parkinson Disease.
What interventions are being tested in trial NCT04728295?
The interventions under investigation include: Exablate 4000 (DEVICE).
Who is sponsoring clinical trial NCT04728295?
This trial is sponsored by InSightec, which has 38 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04728295 being conducted?
This trial has 9 study locations across California, Florida, Illinois, Maryland, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Parkinson Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04728295's enrollment target sits among peer trials
50 155th of 297 higher than 135 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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